Clinical trials: Microbiology
Urinary Tract Infection
Microbiological Characterization and Antibiotic Resistance Profiling of Providencia Spp,: An Emerging Pathogen Isolated From Urinary Tract Infections
Aims of the Research: 1. Isolation and identification of Providencia spp. from UTIs. 2. Genotypic confirmation of Providencia isolates. 3. Determination of antimicrobial sensitivity patterns of isolated Providencia spp. 4.
- Trial name
- NCT07204769
- Testing
- Antibiotic sensitivity
- Where
- Egypt
- Volunteers
- 241 people
- Sponsor
- Assiut University
Cystic Fibrosis
Characterization of Pulmonary Microbiome in Cystic Fibrosis Patients
The composition and role of the pulmonary microbiota is not yet well described in cystic fibrosis patients. The objective of our longitudinal follow-up of primary colonised patients is to show the presence of a link between the…
- Trial name
- SPutOM-CF (NCT04735679)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Dental Caries
Evaluation of the Chemo-mechanical Caries Removal Agent (BRIX3000®) in Primary Molars
Dental caries is one of the most prevalent chronic diseases in people worldwide. Traditional clinical treatment of dental decay has developed on the basis of the removal of carious tissues with high-speed handpieces and…
- Trial name
- NCT05427591
- Testing
- The chemomechanical caries removal agent "BRIX3000®" in group (1A), The traditional surgical treatment in group (1C), The chemomechanical caries removal agent "Carie-CareTM" in group (2B)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Oral Microbiota
Clinical and Microbiological Approach in Orthopedic Treatment of Patients When Choosing a Structural Material
Today, there is a wide range of structural materials on the market, different in chemical, physical and biological properties, and information about them is very often limited only by the manufacturer's instructions, which allows…
- Trial name
- NCT05943197
- Testing
- dental prosthetics, biofilm response and oral microbiota
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Samara State Medical University
Peri-implant Mucositis
Effects of a 0.03% CHX Mouth Rinse in Peri-implant Mucositis
Aim: To evaluate the efficacy of a 0.03% chlorhexidine (CHX) and 0.05% cetyl pyridinium chloride (CPC) mouth rinse, as an adjunct to professionally and patient-administered mechanical plaque removal, in the treatment of…
- Trial name
- NCT03533166
- Testing
- Chlorhexidine
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Universidad Complutense de Madrid
Helicobacter Pylori Infection
A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile
Gastric cancer remains a global health problem, and Chile has one of the highest GC mortality rates in the region. Helicobacter pylori (H.
- Trial name
- NCT05926804
- Testing
- Lansoprazole, Amoxicillin, Clarithromycin
- Where
- 3 sites in Chile
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Miguel O'Ryan Gallardo
HELICOBACTER PYLORI INFECTIONS
Feasibility Study to Diagnose Helicobacter Pylori in the Paediatric Population Using Non-invasive Fecal Analysis
Helicobacter pylori infection is a widespread bacterial disease affecting nearly half of the world's population. In children, the infection displays distinct features versus adults, with lower prevalence, variable symptoms, and…
- Trial name
- HEPYCA (NCT07083804)
- Testing
- Gastric biopsies, Stool sampling
- Where
- France
- Volunteers
- 188 people
- Sponsor
- Poitiers University Hospital
Protracted Bacterial Bronchitis
Antibiotics, Microbiology and Immunology in Children With Chronic Wet Cough - the AMIC Study
The AMIC study is a double-blind, placebo-controlled, multicenter, nationwide, randomized controlled academic pharmaceutical trial.
- Trial name
- AMIC (NCT06020716)
- Testing
- Amoxicillin-Clavulanate 400 Mg-57 Mg/5 mL Oral Powder for Reconstitution
- Where
- 7 sites in Norway
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Cystic Fibrosis, Pseudomonas Aeruginosa
A Comparator Study Evaluating Microbiological Resistance and Effects of Alternating Inhaled Antibiotic Therapies
This is a pilot study of inhaled antibiotic regimens is a pilot study examining clinical and laboratory endpoints of patients on inhaled antibiotic treatments.
- Trial name
- NCT01319253
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Indiana University
Pericoronitis
Evaluation of Photodynamic Therapy in Pericoronitis
In order to reduce the chances of systemic dissemination of the infection and the use of antibiotics, it is mandatory to test effective treatments in the initial phase of pericoronitis aiming to avoid the evolution of the…
- Trial name
- pdt (NCT03576105)
- Testing
- irrigation /sterile saline, Conventional methylene blue as photosensitizer, Methylene blue for oral use as photosensitizer
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Oral Microbial Load
Antibacterial Effect of Moringa Mouthwash in Children With Mixed Dentition Wearing Orthodontic Appliances
This randomized controlled study aims to evaluate the microbiological effectiveness of Moringa mouthwash in children with mixed dentition wearing removable orthodontic appliances.
- Trial name
- MOR-MW (NCT07536438)
- Testing
- Moringa mouthwash, Oral Hygiene Routine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Scabies, Yaws
Azithromycin - Ivermectin Mass Drug Administration for Skin Disease
This is an open-label prospective community intervention trial to assess the impact of community mass treatment with azithromycin for yaws and ivermectin for scabies, on non-yaws bacterial skin infections.
- Conditions
- Scabies, Yaws, Impetigo
- Trial name
- AIM-Skin (NCT02775617)
- Testing
- Ivermectin, Azithromycin, Permethrin
- Where
- Solomon Islands
- Volunteers
- 1,291 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Neck Abscess
Microbiological Study in Neck Space Infections: A Clinical and Microbiological Correlation
Analyze the microbiological spectrum of neck space infections and correlate it with clinical outcomes, with the goal of improving diagnostic and therapeutic approaches to these potentially serious infections \& to assess the…
- Trial name
- NCT07184515
- Volunteers
- 50 people
- Sponsor
- Assiut University
Periodontitis, Surgery
Metronidazole vs Placebo as Adjuncts to Periodontal Surgery for Patients Positive to Porphyromonas Gingivalis
The objective of this study is to determine whether the use of a systemic antimicrobial (metronidazole) as an adjunct to periodontal surgery provides additional clinical and microbiological beneficial effects compared to…
- Trial name
- NCT03880448
- Testing
- Metronidazole, periodontal surgery
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Sepsis, Bloodstream Infection
Microbiology Operations & Time Optimization in Sepsis
The goal of this study is to simulate turn-around times of blood cultures from blood culture collection to final communication of the result.
- Conditions
- Sepsis, Bloodstream Infection, Bacterial Infections, Septic Shock
- Trial name
- MOTION-Sepsis (NCT07817043)
- Testing
- laboratory infrastructure
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- University Medicine Greifswald
Environmental Microbiology, Equipment Contamination
Bacterial Contamination of Anaesthetists' Hands by Personal Mobile Phones Used in the Operating Theatre
The use of mobile phones in the operating room (OR) has become widespread, because of the lack of reports on serious problems. Since mobile phones are used in close body contact and since, as for most non-medical electronic…
- Conditions
- Environmental Microbiology, Equipment Contamination, Personnel, Hospital
- Trial name
- NCT00416936
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Covid19
Spanish Study to Analyze the Histopathological, Ultrastructural and Microbiological Findings Obtained in Autopsies of Patients Who Died Due to COVID-19
The aim of this study is prospectively analyzing the histopathological, ultrastructural and microbiological findings from autopsies performed on patients with COVID-19.
- Trial name
- NCT04772833
- Testing
- Autopsy
- Where
- 10 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Apexification, Root Canal Therapy
Antimicrobial Pastes and Clinical Cases of Apexogenesis
The aim of this study was to perform a clinical and microbiological evaluation of teeth with incomplete apexogenesis and traumatic necrosis that were treated with a revascularization technique, evaluating the microbial reduction…
- Conditions
- Apexification, Root Canal Therapy, Dental Trauma
- Trial name
- NCT03112291
- Testing
- Apexification
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Adriana Kelly de Sousa Santiago Barbosa
COVID-19
Minimal Invasive Autopsies to Investigate Changes in Deceased COVID-19 Patients
Rationale In a very short time corona virus disease 2019 (COVID-19) has become a pandemic with high morbidity and mortality. The main cause of death is respiratory failure including acute respiratory distress syndrome, however…
- Trial name
- MIA-COVID-19 (NCT04366882)
- Testing
- CT-scan with minimal invasive autopsy
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Jessa Hospital
Blepharospasm, Hemifacial Spasm
Post Marketing Surveillance Study of Dysport
The purpose of this study is to provide further information regarding the risks and benefits of Dysport in marketed indications.
- Conditions
- Blepharospasm, Hemifacial Spasm, Cervical Dystonia, Spasmodic Torticollis
- Trial name
- NCT00210431
- Where
- 36 sites in France, Germany and 1 more
- Volunteers
- 783 people
- Sponsor
- Ipsen