Clinical trials: Microbiology
Urogynaecology
A Study of the Effect of Antibiotics on the Microbiology of the Bladder in Patients With Overactive Bladder
The concept of organisms living on or in the human body without causing overt signs of an infection is common in medicine and has been termed a microbiome.
- Trial name
- NCT02536872
- Testing
- None - this is a prospective observational study. Patients will be prescribed their usual treatment (antibiotics) and the effect on urine studied
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Medway NHS Foundation Trust
Nervous System Lyme Borreliosis
Study on Early Lyme Neuroborreliosis
The purpose of this study is to determine clinical course and the sequelae of early Lyme neuroborreliosis after treatment with ceftriaxone.
- Trial name
- NCT00910533
- Testing
- ceftriaxone
- Where
- Slovenia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Infections Nervous System, Nosocomial Infection
Infections Following NeuroSurgery (INS)
Neurosurgery (NS) is essential for the treatment of various diseases such as malignant tumors, vascular conditions, spinal stenosis or trauma.
- Conditions
- Infections Nervous System, Nosocomial Infection, Bacterial Infections, Antibiotic Resistant Infection
- Trial name
- INS (NCT03857295)
- Testing
- No interventions
- Volunteers
- 150 people
- Sponsor
- Neuromed IRCCS
Tracheostomy Complication
Microbiological Evaluation of the Efficacy of Water to Clean Tracheostomy Inner Cannulas
Biofilms pose a potential risk with reusable inner cannulas, by increasing the risk of infection. Effective decontamination is vital in eliminating these biofilms.
- Trial name
- NCT04565405
- Testing
- Detergent, Sterile water
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Changi General Hospital
Prosthetic Vascular Graft Infection
Vascular Graft Infections
Background: Vascular grafts are increasingly implanted due to an increasing prevalence of atherosclerosis and diabetes, and about 1-6% of vascular procedures are complicated by infection.
- Trial name
- VASGRA (NCT01821664)
- Testing
- Prosthetic vascular graft
- Where
- Switzerland
- Volunteers
- 1,800 people
- Sponsor
- University of Zurich
Quality of Life, Oral Mucositis
Efficacy of a Probiotic and Microbiological Analysis on Oral Complications in Patients With HNC
The study is a Clinical Trial and the main objective is to Evaluate the effects of probiotics on oral complications induced by antineoplastic therapies in patients with head and neck cancer, attended at the radiotherapy service…
- Conditions
- Quality of Life, Oral Mucositis, Dental Plaque, Periodontal Diseases
- Trial name
- HNC (NCT06122636)
- Testing
- The probiotic to be used in the intervention corresponds to PRODEFEN Plus manufactured by ITALFARMACO S.A. laboratory
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- University of Barcelona
Preeclampsia, Periodontal Disease
Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease
The primary objective of the study is to assess the incidence and severity of the periodontal infection of patients with preeclampsia.
- Trial name
- NCT03603236
- Testing
- preeclampsia, control
- Where
- 5 sites in Turkey (Türkiye), United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Acne Vulgaris
Evaluation of Topical Dutasteride as a Potential New Therapy for Facial Acne Vulgaris Versus the Triple Combination Therapy (Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel)
Acne vulgaris (AV) is one of the most prevalent dermatological conditions worldwide, affecting approximately 85% of adolescents and young adults between the ages of 12 and 24 years .While acne is often self-limiting, it can have…
- Trial name
- NCT07421804
- Testing
- topical dutasteride
- Volunteers
- 50 people
- Sponsor
- Assiut University
Bacterial Infections, Fungal Infections
MALDITOF Versus Routine Clinical Microbiology for Identifying Pathogens; a Randomized Diagnostic Trial
MALDI-TOF MS is capable of directly identifying bacteria and fungi in positive blood cultures, which may be beneficial to patient management.
- Trial name
- MALDITOF (NCT02306330)
- Testing
- Malditof, Routine clinical microbiology
- Where
- 2 sites in Vietnam
- Volunteers
- 802 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Acne Vulgaris
Acne Vulgaris Related Microbiology and Serology
This will be an investigation to determine the quality of the serological immune responses against Propionibacterium acnes (P. acnes) in acne patients compared to healthy individuals.
- Trial name
- NCT04056598
- Testing
- Study of humoral immunity
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sanofi
Pulp Disease, Dental
Evaluation of Different Materials in Pulpotomy of Primary Molars
The aim of the current study is to evaluate and compare clinical and radiographic success and antibacterial effect of Hyaluronic Acid and Amniotic membrane pulpotomy in primary molars in comparison with MTA pulpotomy (Randomized…
- Trial name
- NCT05981352
- Testing
- mineral trioxide aggregate pulpotomy, Dehydrated amniotic membrane pulpotomy, Hyaluronic acid pulpotomy
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Endodontic Disease, Root Canal Infection
Comparison of Antibacterial Efficacy of Three Final Irrigants
This study was conducted to determine the antibacterial affect of three different solutions used as final irrigant during endodontic therapy.
- Trial name
- NCT03853200
- Testing
- QMix Root Canal Irrigant, 17%EDTA+2%Chlorhexidine, EDTA
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Halitosis
Effect of Photodymamic Therapy With Urucum and LED in the Reduction of Halitosis
Halitosis, also known as bad breath, is a term used to define an unpleasant and foul odor that emanates from the mouth and may have local or systemic origin.
- Trial name
- NCT03346460
- Testing
- Tongue Scraping, aPDT, Tongue scraper and aPDT
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Periodontitis, Alzheimer Disease
Nalysis of the Periodontal Microbiota in Elderly Subjects With and Without Alzheimer's Disease: a Case Control Study
The neurological disorders that accompany aging represent a major public health problem. The management of these diseases is a major medical and social priority.
- Trial name
- ORAMICAL (NCT05077618)
- Testing
- sampling of dental plaque and blood sample during the treatment
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Memory Deficits, Mood Change
The Effects of Microbiological Spectrum Changes to Improve Cognitive Health in Aging Population
The goal of this project is to develop probiotic dietary supplements intended for the elderly, which can modify the composition of the intestinal microbiota typically occurring in the aging population.
- Conditions
- Memory Deficits, Mood Change, Gut Health, Aging Problems
- Trial name
- CleverAgeBiota (NCT05051501)
- Testing
- Probiotics C2P
- Where
- 2 sites in Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health, Czech Republic
Chronic Periodontitis
Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis
This study was carried out in the Department of Periodontology and source of patient was be from the outpatient section of Tatyasaheb Kore Dental College \& Research Centre, New Pargaon.
- Trial name
- NCT03516370
- Testing
- Saccharomyces Boulardii 250 MG
- Where
- India
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Artificial Intelligence, Machine Learning
Appropriate Use of Blood Cultures in the Emergency Department Through Machine Learning
The goal of this clinical trial is to study whether the use of our blood culture prediction tool is non-inferior to current practice and if it can improve certain outcomes in all adult patients presenting to the emergency…
- Conditions
- Artificial Intelligence, Machine Learning, Microbiology, Emergency Service, Hospital
- Trial name
- ABC (NCT06163781)
- Testing
- Blood culture prediction tool
- Where
- Netherlands
- Volunteers
- 7,584 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Split-skin Grafted Third-degree Burn Wound
Trial of Different Wound Dressings in Split-skin Grafted Third Degree Burns
In plastic and reconstructive surgery, treatment strategies of second-degree burn wounds and split-skin grafted third-degree burn wounds aim at reducing infection and improving reepithelialization.
- Trial name
- NCT03674151
- Testing
- Silver Nylon dressing, Manuka-Honey, Povidone-Iod (PVP-Iod)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Schleswig-Holstein
Mucositis, Peri-implantitis
Effect of Probiotic Lactobacillus Reuteri in the Treatment of Mucositis and Periimplantitis
Evaluate clinically and microbiologically the effect of the oral probiotic Lactobacillus reuteri Prodentis (PerioBalance®, Sunstar, Switzerland) on implants with mucositis or periimplantitis, as a coadjuvant treatment of…
- Trial name
- NCT03047291
- Testing
- Probiotic
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Apexification, Root Canal Therapy
Antimicrobial Pastes and Clinical Cases of Apexogenesis
The aim of this study was to perform a clinical and microbiological evaluation of teeth with incomplete apexogenesis and traumatic necrosis that were treated with a revascularization technique, evaluating the microbial reduction…
- Conditions
- Apexification, Root Canal Therapy, Dental Trauma
- Trial name
- NCT03112291
- Testing
- Apexification
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Adriana Kelly de Sousa Santiago Barbosa