Clinical trials: Middle Ear Disease
Cleft Lip and Palate
Evaluation of the Effect of Prosthetic Management for Congenital Cleft Lip and Palate Infants on the Middle Ear Function
Aim of the study was to evaluate the effect of feeding appliance for congenital cleft lip and palate infants on the middle ear function
- Trial name
- NCT06075069
- Testing
- Feeding appliance
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Hearing Loss, Bilateral
Sentence Shaping - DHH
The proposed research addresses a long-standing and important challenge of improving literacy skills of children who are deaf and hard of hearing, a historically under researched group.
- Trial name
- NCT06860022
- Testing
- Shape Coding
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University
OTITIS MEDIA WITH EFFUSION
Tympanostomy Tube Extrusion Time & Viscosity
Studies have focused on the factors that influence tympanostomy tube (TT) extrusion may contribute to the management of OME. In this study the investigators aimed to assess the correlation between the TT extrusion time and…
- Trial name
- NCT03848026
- Testing
- Middle ear fluid viscosity, Tympanostomy tube extrusion time
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Bezmialem Vakif University
Eustachian Tube Dysfunction
Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction
The aim of this study is to determine which of the many Eustachian tube function tests (or combination of tests) is most helpful in finding out what is causing ear problems in children and adult patients with middle-ear diseases…
- Trial name
- NCT01974726
- Testing
- ET Stress test, Sonotubometry, Forced Response Test (FRT)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Deaf, Hard of Hearing
Effectiveness of Integrative Therapy on Psychological Hardiness Among Hard-of-Hearing Female Students
The goal of this clinical trial (quasi-experimental study) is to learn whether an integrative therapeutic program can enhance psychological hardiness among hard-of-hearing (HOH) female students in Saudi Arabia (Al-Ahsa…
- Conditions
- Deaf, Hard of Hearing, Hearing Disability
- Trial name
- Integrative (NCT07514468)
- Testing
- Integrative Therapeutic Program
- Where
- Saudi Arabia
- Volunteers
- 25 people
- Sponsor
- King Faisal University
Middle Ear Cholesteatoma
How Long Must the MRI Follow-up Last to Safely Identify Middle Ear Residual Cholesteatoma
Previous studies demonstrated the high diagnostic value of non-echoplanar diffusion weighted magnetic resonance imaging (non-EP DWI) for residual cholesteatoma.
- Trial name
- NCT04489550
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Montpellier
Otitis Media, Middle Ear Infections
Post-Market Clinical Follow-Up Study of the Solo+ Tympanostomy Tube Device
The purpose of this project is to collect information from the doctor notes about the use of the device, to monitor the tubes after surgery, and collect information from patients and parents/guardians about their views on the…
- Trial name
- NCT07029997
- Testing
- Solo+ Tympanostomy Tube Device (Solo+ TTD)
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- AventaMed DAC
Otitis Media
A Study of the Effectiness and Safety of Levofloxacin in Treating Children With a Rapid and Severe Onset of Infection and Inflammation of the Middle Ear That is Difficult to Treat
The purpose of the study is to assess the rate of elimination of bacteria by levofloxacin in middle ear fluid of children with a rapid and severe onset of infection and inflammation of the middle ear who are at high risk for…
- Trial name
- NCT00044473
- Testing
- levofloxacin
- Volunteers
- 206 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Otitis Media With Effusion (OME), Eustachian Tube Dysfunction
Autoinflation as a Eustachian Tube Rehabilitation
This randomized controlled trial evaluated the effectiveness of autoinflation in preventing recurrence of otitis media with effusion (OME) and reducing the need for reoperation after tympanostomy tube (TT) extrusion in children.
- Trial name
- NCT07122999
- Testing
- Eustachi
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Pusan National University Hospital
Chronic Otitis Media, Age Determined Bacteria
Bacterial Assessment of Middle Ear Fluid in Children Undergoing Ventilation Tube Placement Surgery
Children with chronic otitis media have more resistant bacteria that require surgical intervention to eradicate the infections. The study will evaluate the dominant bacteria and their sensitivities to antibiotics.
- Trial name
- NCT01157910
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Acute Otitis Media
Clinical Study to Assess the Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Middle Ear Infections in Pediatric Patients
The purpose of this study is to determine if the combination of DF289 plus DF277 is safe and effective in treating middle ear infections in children with ear tubes.
- Trial name
- NCT01395966
- Testing
- DF289, DF277, DF289 plus DF277
- Where
- Spain
- Volunteers
- 331 people
- Sponsor
- Salvat
Otitis Media, Serous, Negative Middle Ear Pressure
Short Term Relief of Eustachian Tube Dysfunction and Serous Otitis Media Using Intranasal Steroid Sprays
We hypothesize that intranasal steroid application will have a beneficial therapeutic effect in adults with regard to resolution of serous otitis media and/or negative middle ear pressure, as compared to placebo.
- Conditions
- Otitis Media, Serous, Negative Middle Ear Pressure, Rhinitis, Otitis Media With Effusion
- Trial name
- NCT00279916
- Testing
- Triamcinolone acetonide nasal spray
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Mayo Clinic
Otitis Media With Effusion
OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
The purpose of this study is to confirm the effectiveness, safety and tolerability of OTO-201 in the treatment of pediatric subjects with bilateral middle ear effusion who require tympanostomy tube placement.
- Trial name
- NCT01949155
- Testing
- OTO-201
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Otonomy, Inc.
Otitis Media With Effusion, Healthy
The URT and Middle Ear Microbiota in Health and During Chronic OME
This study analyses which bacteria are present in the middle ear space and adjacent upper respiratory tract niches in healthy people and in patients suffering from chronic otitis media with effusion (OME; glue ear).
- Trial name
- NCT03109496
- Testing
- Collection of body fluids/swabs
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Antwerp
Otitis Media, Otitis Media Chronic
SWIR Otoscopy Study
The aim of this study is to provide preliminary data to support future studies to demonstrate that the short wave infrared (SWIR) otoscope is a better diagnostic tool than a white light otoscope for diagnosing middle ear…
- Conditions
- Otitis Media, Otitis Media Chronic, Otitis Media Effusion
- Trial name
- NCT06944795
- Testing
- SWIR device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Secretory Otitis Media, Acute Otitis Media
The Effect of Early Non-Surgical Treatment of Children With Middle Ear Effusion on the Hearing
Secretory otitis media (SOM) or middle ear effusion is a common finding after acute otitis media (AOM). It is usually associated with 5-15 deci Bells hearing loss.
- Trial name
- NCT02549612
- Testing
- Moniri Otovent
- Volunteers
- 80 people
- Sponsor
- Vastra Gotaland Region
Adenoid Hypertrophy, Middle Ear Effusion
It is Accepted That Adenoid Hypertrophy is Related to Otitis Media With Effusion Incidence. Better Understanding of the Correlation Between the Relative Size of AH and the Incidence of Persistent OME May Provide Evidence to Support a More Standardized Approach to the Diagnosis and Treatment of OME.
The aim of this study is to further investigate the correlation between Site and size of adenoid hypertrophy and middle ear effusion in order to provide evidence for designing a more standardized approach to the diagnosis and…
- Trial name
- NCT06674720
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Otitis Media With Effusion
Osteopathic Otitis Media Research Study
The purpose of this study is to determine if the application of osteopathic manipulative medicine speeds the rate of resolution of middle ear effusion (fluid) in children following an episode of acute otitis media.
- Trial name
- OOMRS (NCT00520039)
- Testing
- osteopathic manipulative medicine (OMM)
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- West Virginia School of Osteopathic Medicine
Upper Respiratory Infection, Acute Otitis Media
Lactobacillus Rhamnosus GG in the Middle Ear and Adenoid Tonsil
The purpose of this study is to evaluate the effect of oral administration of probiotic Lactobacillus rhamnosus GG in middle ear and adenoid tonsil.
- Trial name
- NCT02110732
- Testing
- Lactobacillus rhamnosus GG
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Hearing Disorders
Middle-ear Reflex Testing Using Wideband Acoustic Immittance
This project will assess the middle-ear muscle reflex using wideband acoustic immittance which is a valuable method for evaluating infants, children, and adults.
- Trial name
- WAI-MEMR (NCT04875637)
- Testing
- WAI-MEMR
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Mimosa Acoustics