Clinical trials: Mobilization
Hip; Anomaly
Comparing the Effects of Mobilization With Movement (MWM), Self MWM, and Dynamic Stretching on Hip Internal Rotation)
This study is looking to address the effectiveness of three different intervention on hip range of motion. There will be a therapist performed mobilization group, a self mobilization group, and a dynamic stretching group.
- Trial name
- NCT04279756
- Testing
- Hip Mobilization with Movement, Self-Mobilization with Movement, Dynamic Stretch
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Anemia, Aplastic
Flu+CPM+rATG Conditioning Regimes for Unrelated Bone Marrow Transplantation (UBMT)(or Mobilized Peripheral Blood)in Severe Aplastic Anemia (SAA)
Anti-thymocyte globulin (ATG) has been used in severe aplastic anemia as a part of the conditioning regimen. Among the many kinds of ATG preparations, thymoglobulin had been found to be more effective in preventing GVHD and…
- Trial name
- NCT00737685
- Testing
- cyclophosphamide, fludarabine , thymoglobulin
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- The Korean Society of Pediatric Hematology Oncology
Fanconi Anemia
Clinical Phase II Trial to Evaluate CD34+ Cells Mobilization and Collection in Patients With Fanconi Anemia for Subsequent Transduction With a Lentiviral Vector Carring FANCA Gene. FANCOSTEM-1
Fanconi anemia (FA) is a congenital disease characterized by bone marrow failure and increased incidence of malignant tumors. The Project pursue the optimization of the collection of hematopoietic progenitor cells for later use…
- Trial name
- NCT02931071
- Testing
- filgrastim, plerixafor
- Where
- 2 sites in Spain
- Volunteers
- 13 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
ICU, Critical Illness
Paediatric Early Rehabilitation/Mobilisation During InTensive Care
In the UK, critical illness or injury affects about 19,000 Children and Young Persons (CYP) every year who are admitted to the paediatric intensive care unit (PICU) to receive life-sustaining treatments.
- Trial name
- PERMIT (NCT04110938)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Birmingham
Hip Adduction Strength, Groin Pain
The Effect of Mulligan's Mobilization with Movement Versus Dry Needling on Pain,Function,and Range of Motion Among Athletes with Hip Adductor Related Groin Pain and Dysfunction
This study aims to highlight and investigate the effectiveness of two common management practices in physiotherapy, dry needling intervention as a soft tissue technique and Mulligan mobilization with movements MWM as a joint…
- Conditions
- Hip Adduction Strength, Groin Pain, Groin Injury
- Trial name
- NCT06841588
- Testing
- Mulligan's Mobilization with Movement and Dry Needling, Dry Needling (DN)
- Where
- Palestinian Territories
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Rectal Cancer Surgery
Comparison of Different Surgical Approaches in Female Rectal Cancer.
Mid-to-low rectal cancer exhibits an extremely high incidence rate in China. Currently, the primary treatment approach for mid-to-low rectal cancer remains surgical intervention, with total mesorectal excision (TME) being the…
- Trial name
- NCT07189780
- Testing
- Surgical approach
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Burn Scar
Scar Mobilization Improves Scars and Quality of Life in Burned Children.
This quasi-experimental study evaluates the effect of scar tissue mobilization on scar thickness, pliability, and quality of life in children with upper extremity burns.
- Trial name
- NCT07578883
- Testing
- Scar tissue mobilization
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Mobilizing Community Systems to Engage Families in Early Autism Spectrum Disorder (ASD) Detection & Services
This multisite study will compare the effectiveness of universal screening by 3 community service systems using Autism Navigator, a highly interactive web platform that includes an automated screening tool, information about…
- Trial name
- NCT02445105
- Testing
- Autism Navigator Enhanced Practice, Family Engagement plus Autism Navigator
- Where
- 4 sites in United States
- Volunteers
- 10,857 people
- Sponsor
- Florida State University
Adverse Event
Adverse Events Associated With Manual Therapies in Children
This study aims to evaluate the feasibility to conduct a prospective cohort study evaluating the adverse events associated with manual therapies in children of 5 years and younger.
- Trial name
- NCT05409859
- Testing
- Manual therapies
- Where
- Canada
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières
Immunosuppression, Leukemia
Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignances
This study will evaluate the safety and effectiveness of stem cell transplantation in which the donor s T cells (a type of lymphocyte, or white blood cell) have been removed and then added back.
- Trial name
- NCT00353860
- Testing
- SOLEX 300i Stem Cell Selection
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Graft vs Host Disease, Hematologic Neoplasm
Bone Marrow Transplant Studies for Safe and Effective Treatment of Leukemia
Bone marrow transplants (BMT) are one of the accepted therapies used to treat leukemia. However, BMT have risks of complications. One potentially life-threatening complication is known as graft-versus-host disease (GVHD).
- Conditions
- Graft vs Host Disease, Hematologic Neoplasm, Leukemia, Multiple Myeloma
- Trial name
- NCT00001623
- Testing
- Allogeneic Bone Marrow Transplant
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sickle Cell Anemia
Haploidentical PBMC Transplant for Severe Congenital Anemias
Background: Bone marrow transplantation (BMT), which involves transplanting a donor's marrow stem cells, is capable of curing some congenital anemias.
- Trial name
- NCT00977691
- Testing
- PBSC Transplant, Alemtuzumab, Sirolimus
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cleft Lip Palate
Quadratus Lumborum Block for Iliac Bone Harvest in Pediatric Cleft Alveolus Repair
This prospective, randomized, double-blinded controlled trial will investigate the effectiveness of a lateral quadratus lumborum (QL) block in 50 children aged 6-14 years undergoing iliac crest bone grafting for cleft alveolus…
- Trial name
- NCT07846761
- Testing
- Lateral quadratus lumborum block
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Sickle Cell Disease
Peripheral Blood Stem Cell Collection From Patients With Sickle Cell Disease (SCD) Using Plerixafor
With recent advances in gene editing, gene therapy is becoming a viable curative treatment option for sickle cell disease. In order to do genetic manipulation, investigators need to collect hematopoietic stem cells from patients…
- Trial name
- NCT04817345
- Testing
- Plerixafor
- Sponsor
- St. Jude Children's Research Hospital
Lymphoma, Non-Hodgkin, Lymphoma, Hodgkin
Low Dose Plerixafor Plus G-CSF in Mobilizing Stem Cells for Autologous Peripheral Blood Transplantation
Plerixafor, is added to mobilizing chemotherapy and G-CSF to overcome poor stem cell mobilization. We want to demonstrate that half of the commonly prescribed dose can be safely administered once as a single dose in first attempt…
- Conditions
- Lymphoma, Non-Hodgkin, Lymphoma, Hodgkin, Myeloma, Stem Cell Transplant Complications
- Trial name
- NCT03244930
- Testing
- Plerixafor 0.12 mg/kg
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndrome
Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer
This randomized phase II trial studies how well giving tacrolimus and mycophenolate mofetil (MMF) with or without sirolimus works in preventing acute graft-versus-host disease (GVHD) in patients undergoing donor stem cell…
- Conditions
- Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndrome, Refractory Chronic Lymphocytic Leukemia, Refractory Plasma Cell Myeloma
- Trial name
- NCT00105001
- Testing
- Fludarabine Phosphate, Total-Body Irradiation, Peripheral Blood Stem Cell Transplantation
- Where
- 11 sites in United States, Denmark and 1 more
- Volunteers
- 210 people
- Sponsor
- Fred Hutchinson Cancer Center
Spastic Cerebral Palsy (sCP)
Talocrural Mobilization With Movement in Spastic Cerebral Palsy
The aim of this randomized controlled trial is to find the effect of Mulligan's Mobilization with Movement of Talocrural joint in Cerebral Palsy Patients having spasticity on improving Ankle Range of Motion, improving balance and…
- Trial name
- NCT06598657
- Testing
- Mobilization with Movement MWM, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Tendon Injury - Hand
Passive Mobilization With Place and Hold vs Active Mobilization Therapy After Flexor Tendon Repair
The aim of this study is to investigate if active mobilisation after flexor tendon repair in fingers gives better range of motion, strength, risk of rupture and patient satisfaction compared with passive mobilisation with place…
- Trial name
- NCT04385485
- Testing
- Active mobilisation, Passive mobilisation with place and hold
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Sahlgrenska University Hospital
Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific
Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Biological Therapy in Treating Patients With Solid Tumors or Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Conditions
- Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific
- Trial name
- NCT00027937
- Testing
- aldesleukin, filgrastim, sargramostim
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Lead, Blood, Pregnancy
Dietary Calcium Supplementation to Reduce Blood Lead in Pregnancy
Lead accumulates in bone. During pregnancy, physiologic changes occur prompting bone resorption in order to provide calcium to the growing fetal skeleton also release the lead stored in bone into a pregnant woman's circulation.
- Conditions
- Lead, Blood, Pregnancy, Bone Resorption
- Trial name
- NCT00558623
- Testing
- calcium carbonate
- Where
- Mexico
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)