Clinical trials: Moderate Acute Malnutrition
Severe Acute Malnutrition, Moderate Acute Malnutrition
Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition
This single-center, randomized, open-label trial will compare the safety of MTT delivered by rectal catheter enema in participants 12-60 months of age with malnutrition (moderate acute malnutrition [MAM] or severe acute…
- Trial name
- THRIVE (NCT03087097)
- Testing
- Fecal Microbiota Transplantation
- Where
- South Africa
- Volunteers
- 5 people
- Sponsor
- Microbiome Health Research Institute
Malnutrition
Package of Interventions After Recovering From Moderate Acute Malnutrition
Children who recover from moderate acute malnutrition in Malawi remain at high risk for relapse or death in the year following recovery.
- Trial name
- NCT02351687
- Testing
- Lipid Nutrient Supplement, Sulfadoxine-pyrimethamine, Albendazole
- Where
- Malawi
- Volunteers
- 1,499 people
- Sponsor
- Washington University School of Medicine
Marasmus, Kwashiorkor
Mothers Understand And Can do it - Mid Upper Arm Circumference Screening for Malnutrition Performed by Mothers
PRIMARY OBJECTIVE : To determine whether mothers, given minimal group training, are capable of using a MUAC (mid-upper arm circumference) bracelet to screen their children for malnutrition and categorise them into one of three…
- Conditions
- Marasmus, Kwashiorkor, Malnutrition; Degree, Moderate, Malnutrition
- Trial name
- MUAC (NCT01790815)
- Where
- Niger
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Alliance for International Medical Action
Acute Malnutrition in Childhood, Acute Malnutrition, Severe
Reduced Dosage and/or Visitation Protocol for the Treatment of Acute Malnutrition in Kenya
Severe acute malnutrition (SAM) places children at significant risk of mortality. Outpatient treatment programs are effective but there is a need to increase treatment coverage and reduce costs of treatment.
- Conditions
- Acute Malnutrition in Childhood, Acute Malnutrition, Severe, Acute Malnutrition, Moderate, Wasting
- Trial name
- RSWITCH (NCT07420062)
- Testing
- WHO-reduced, WHO-full, Kenya-IMAM
- Where
- Kenya
- Volunteers
- 2,274 people
- Sponsor
- International Food Policy Research Institute
Malnutrition
Whey Permeate Study
This is a prospective, randomized, double-blinded, controlled clinical effectiveness trial of two supplementary foods in the treatment of MAM.
- Trial name
- NCT01790048
- Testing
- Whey permeate RUSF, Soy Protein RUSF
- Where
- Malawi
- Volunteers
- 2,259 people
- Sponsor
- Washington University School of Medicine
Moderate Acute Malnutrition (MAM)
Development, Feasibility and Acceptability of Recipes for Locally Available, Specially Formulated Foods for the Management of Moderate Acute Malnutrition in Niger (Related to NCT06382857 Protocol)
The study consisted of two phases. Phase 1 was a recipe development phase, which aimed to identify recipes that meet ≥80% of the recommended nutrient profile for Specially Formulated Foods (SFF) used in the standard management of…
- Trial name
- LAF (NCT07506213)
- Testing
- Locally Available Food
- Where
- Niger
- Volunteers
- 30 people
- Sponsor
- Epicentre
Moderate Acute Malnutrition (MAM)
Comparison of Four Different Supplementary Foods in the Treatment of Moderate Acute Malnutrition (MAM) in Children in Sierra Leone: a Cluster-randomised, Controlled Clinical Effectiveness Trial
The objective of this study is to test and compare the effectiveness and cost-effectiveness of four supplementary foods for the treatment of moderate acute malnutrition (MAM) in normal programmatic settings in Sierra Leone.
- Trial name
- NCT02077907
- Testing
- Super Cereal Plus (SC+), Super Cereal (SC), fortified oil, sugar, Plumpy Sup
- Volunteers
- 1,147 people, healthy volunteers welcome
- Sponsor
- Tufts University
Severe Acute Malnutrition, Moderate Acute Malnutrition (MAM)
Regular Growth Monitoring (RGM) of Young Children in Guinea-Bissau
Wasting (severe thinness) is a common and serious problem among young children in rural Guinea-Bissau. Community Health Agents (CHAs) can help prevent malnutrition by regularly measuring children's growth and advising families on…
- Trial name
- NCT07584395
- Testing
- Regular Growth Monitoring (RGM) by Community Health Agents
- Where
- Guinea-Bissau
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Acute Malnutrition in Infancy (Disorder)
Optimizing Acute Malnutrition Management in Children Aged 6 to 59 Months in Niger (OptIMA Niger)
Acute malnutrition (AM) is a continuum condition, arbitrarily divided into severe and moderate categories (SAM, MAM) which are managed separately, with programs overseen by different agencies with different products and supply…
- Trial name
- NCT04698070
- Testing
- Nutritional Strategy - OptiMA, Nutritional Strategy - ComPAS, National nutritional Strategy (Niger)
- Where
- 4 sites in Niger
- Volunteers
- 2,304 people
- Sponsor
- Alliance for International Medical Action
Malnutrition
Comparison of a Two Ready-to-use Supplementary Foods of Differing Protein Quality for the Treatment of MAM.
This is a prospective, randomised, double-blinded, controlled clinical effectiveness trial of two supplementary foods in the treatment of MAM. The setting will be 21 rural sites in southern Malawi.
- Trial name
- NCT03549156
- Testing
- C-RUSF, HIPRO RUSF
- Where
- Malawi
- Volunteers
- 1,858 people
- Sponsor
- Washington University School of Medicine
Child, Malnutrition
Effectiveness of a Ready-to-Use-Food (RUF) Supplement to Prevent Acute Child Malnutrition
The overall objective of this project is to assess the effectiveness and cost-effectiveness of RUF (ready-to-Use Food, Plumpy Doz(r)) to prevent moderate acute malnutrition in children aged 6-36 months if embedded in a program of…
- Trial name
- PREAMA (NCT01154595)
- Testing
- Plumpy Doz(r) - Ready-to-Use Food, Food-for-Training
- Where
- Chad
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Action Contre la Faim
Malnutrition; Moderate
Effectiveness, Tolerability and Safety of Three Formulations in Underfives With Moderate Acute Malnutrition
This is a randomized clinical trial aimed at evaluating the effectiveness, tolerability and safety of standardized milk-based formulation, standardized non-milk based formulation and a hospital-based formulation in the management…
- Trial name
- NCT04323059
- Testing
- Standardized milk-based formulation
- Where
- 3 sites in Nigeria
- Volunteers
- 80 people
- Sponsor
- Dr. Ekong E. Udoh
Acute Malnutrition in Childhood, Wasting
Treatment of Acute Malnutrition in Outpatient Care Services in Venezuela: a Prospective Cohort Research
The goal of this observational study is to compare the effectiveness, safety, and efficiency of the simplified protocol, which includes the following three modifications: a) use of a single treatment product (RUTF), b) reduced…
- Conditions
- Acute Malnutrition in Childhood, Wasting, Child Malnutrition
- Trial name
- NCT06287827
- Testing
- Simplified protocol, Standard protocol
- Where
- 4 sites in Venezuela
- Volunteers
- 299 people
- Sponsor
- UNICEF - Venezuela
Severe Acute Malnutrition, Moderate Acute Malnutrition
Alternative RUTFs for Treatment of Child Wasting
Acute malnutrition is the most life-threatening form of undernutrition. Moderate and severe acute malnutrition (MAM, SAM) are effectively treated with ready-to-use therapeutic foods (RUTFs) but there is a need to lower the cost…
- Conditions
- Severe Acute Malnutrition, Moderate Acute Malnutrition, Wasting
- Trial name
- NCT06912620
- Testing
- Soy-based RUTF, Soy-maize-sorghum-based RUTF, Standard RUTF
- Where
- Burkina Faso
- Volunteers
- 2,269 people
- Sponsor
- International Food Policy Research Institute
Malnutrition
Treatment of High-Risk Moderate Acute Malnutrition Using Expanded Admission Criteria
This project explores whether children have better growth and cognitive development when the clinic identifies "higher risk" MAM children and support them either with the same treatment as SAM children or with the recommended…
- Trial name
- Hi-MAM (NCT03647150)
- Testing
- amoxicillin, Ready-to-use therapeutic food (RUTF), Mother Care group
- Where
- Sierra Leone
- Volunteers
- 1,322 people
- Sponsor
- Washington University School of Medicine
Moderate Acute Malnutrition, Stunting
Eggs for Gut Health
The goal of this clinical trial is to test egg powder supplementation in children with moderate acute malnutrition in Sierra Leone.
- Conditions
- Moderate Acute Malnutrition, Stunting, Environmental Enteric Dysfunction, Severe Acute Malnutrition
- Trial name
- NCT06002438
- Testing
- Whole egg powder, Corn powder, Supercereal Plus
- Where
- 10 sites in Sierra Leone
- Volunteers
- 461 people
- Sponsor
- Washington University School of Medicine
Moderate Acute Malnutrition (MAM)
Management of Children With Moderate Acute Malnutrition in Mali
The objectives of the study are to assess the impact of different dietary strategies for the management of children with MAM on: the children's continued participation in the nutritional rehabilitation program and their physical…
- Trial name
- Mali-MMAM (NCT01015950)
- Testing
- Plumpy'Sup, Local food supplement, Misola
- Where
- Mali
- Volunteers
- 1,260 people
- Sponsor
- Helen Keller International
Moderate Acute Malnutrition
Supplementary Food for Moderate Acute Malnutrition in Children
Children with moderate acute malnutrition will be recruited in order to receive an intervention which consists in the consumption of a single serving of SF-cookies daily, 7-days a week for 12 months and 12 educational sessions on…
- Trial name
- NCT02571764
- Testing
- Nutritional Oats Cookie
- Where
- Mexico
- Volunteers
- 248 people
- Sponsor
- PepsiCo Global R&D
Moderate Acute Malnutrition (MAM), Undernutrition
Effectiveness of Positive Deviance/Hearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh
The goal of this clinical trial (cluster randomized controlled trial) is to learn whether a Positive Deviance/Hearth (PDH) intervention can effectively treat moderate acute malnutrition (MAM) and reduce relapse compared to…
- Conditions
- Moderate Acute Malnutrition (MAM), Undernutrition, Wasting
- Trial name
- PD/Hearth MAM (NCT07591064)
- Testing
- PD/Hearth is a behavioral change program that teaches caregivers how to cook and feed their children. A nutrient-dense meal using local ingredients will be fed to children during Hearth sessions., Standard of Care (Investigator Selected)
- Where
- Bangladesh
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- World Vision US
Wasting, Moderate Acute Malnutrition
Effectiveness of Nutritional Products to Treat Moderate Acute Malnutrition
The purpose of this study is to determine whether an improved corn-soya blend (CSB+) and a new formulated ready-to-use supplementary food (RUSF) are effective in the treatment of moderate acute malnutrition in children.
- Trial name
- NCT01898871
- Testing
- A daily ration of 40 kcal/kg of body weight during 56 days
- Where
- 2 sites in Cameroon
- Volunteers
- 81 people
- Sponsor
- Centre for Food and Nutrition Research, Yaounde