Clinical trials: Moderate Sedation
Undesired Intrauterine Pregnancy, First Trimester Pregnancy
Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions
In the United States, the majority of first-trimester surgical abortions are performed in outpatient clinics that utilize a wide variety of oral and intravenous regimens for pain control.
- Trial name
- NCT01011634
- Testing
- Intravenous moderate sedation versus oral medication
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Conscious Sedation
Adjunctive Atropine During Ketamine Sedation
Ketamine seems an obvious choice in the setting of an emergency department Ketamine leads to increased production of salivary and tracheal secretions Antisialagogues(atropine)therefore have been recommended as a routine adjunct…
- Trial name
- NCT00834470
- Testing
- Atropine
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Failed Conscious Sedation During Procedure
The Efficacy and the Safety of Dexmedetomidine Sedation on the Pediatric Intensive Unit(PICU) Patients.
To observe the efficacy and safety of dexmedetomidine sedation on the patients admitted to the pediatric intensive care unit after surgery.
- Trial name
- NCT02296073
- Testing
- Midazolam, Dexmedetomidine, Fentanyl
- Volunteers
- 120 people
- Sponsor
- Anhui Provincial Children's Hospital
Sedation, Conscious
Intranasal Midazolam in Children as a Pre-Operative Sedative
The purpose of this study is to see if adding a numbing medicine, xylocaine, to the nasal midazolam makes giving the midazolam easier and more comfortable without affecting how the midazolam works as a sedative.
- Trial name
- NCT02314546
- Testing
- Midazolam, xylocaine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Bassett Healthcare
Conscious Sedation
Ondansetron Reduce Vomiting Associated With Ketamine PSA
Ondansetron, a commonly used anti-vomiting medication, may reduce the occurrence of vomiting associated with ketamine during procedural sedation in the pediatric emergency department.
- Trial name
- NCT00387556
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cerebral Palsy
Conscious Sedation With Nitrous Oxide in Control of Stress During Dental Care for Individuals With Cerebral Palsy
Cerebral Palsy induces oral alterations that impact on oral health, requiring dental treatment. The objective of this study was to evaluate the use of conscious sedation with nitrous oxide (N2O) in the control of stress during…
- Trial name
- NCT02322983
- Testing
- Control of Stress
- Where
- Brazil
- Volunteers
- 77 people
- Sponsor
- Universidade Cruzeiro do Sul
Childrens 0 to 18 Years of Age Who Require Moderate Sedation
Sedation for Brainstem Evoked Auditory Response (BEAR) Testing Using Intravenous Pentobarbital
This is a retrospective chart review study (700 charts from 2002 to 2010)of children from 0 to 18 years of age who have undergone Brainstem Evoked Auditory Response (BEAR)testing using midazolam and pentobarbital protocol for…
- Trial name
- NCT01282112
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Akron Children's Hospital
Midazolam
Pharmacokinetic Evaluation of MDZ028
Plasma concentration data were collected from 37 paedriatic patients and 12 healthy adults recruited in a single dose, open-label phase II pharmacokinetic study and in a single dose, randomised, open-label two-peiod crossover…
- Trial name
- MIDAZOLAM (NCT03639428)
- Testing
- Midazolam
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Moderate Sedation, Laceration
Comparison of N2O Inhalation and Ketamine in Pediatric PSA
Ketamine provides effective and relatively safe sedation analgesia for primary closure of lacerated pediatric patients However, deep sedation and adverse effects suggest the opportunity to develop alternative strategies We…
- Trial name
- PSA (NCT00834730)
- Testing
- N2O gas vs ketamine
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Seoul National University Hospital
Failed Moderate Sedation During Procedure, Ketamine Adverse Reaction
Intranasal Ketamine for Pediatric Procedural Sedation: a Feasibility Study
The purpose of this study is to evaluate the feasibility of intranasal ketamine for adequate sedation of children undergoing minor procedures in the Emergency Department.
- Trial name
- NCT03067974
- Testing
- Ketamine Hcl 100Mg/Ml Inj
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Arizona
Sialorrhea
Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine Sedation
The purpose of this study is to determine if the antisialagogues (anti-salivary agents), Atropine and Glycopyrrolate, are effective in reducing hypersalivation when sedating patients with Ketamine for procedural sedation in the…
- Trial name
- NCT01191398
- Testing
- Atropine (0.01mg/kg), Glycopyrrolate (0.01mg/kg), Normal saline 0.9%
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Craig J. Huang
Dental Anxiety
Nebulized Midazolam, Dexmedetomidine, and Their Combination in Sedation of Preschoolers Undergoing Dental Treatment
The aim of the study is to evaluate the effect of nebulized Midazolam, Dexmedetomidine, and their combination as procedural, moderate sedative agents in preschoolers undergoing dental treatment.
- Trial name
- NCT03827408
- Testing
- Midazolam group (MDZ), Dexmedetomidine group (DEX), Combination of Midazolam and Dexmedetomidine (MDZ/DEX)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Nourhan M.Aly
Anti-anxiety Agents, Moderate Sedation
Sublingual Versus Intranasal Administration of Dexmedetomidine for Sedation of Children Undergoing Dental Treatment
The aim of this study is to assess the efficacy of Dexmedetomidine drug either used sublingually or intranasally in managing healthy children during dental treatment
- Trial name
- NCT04237532
- Testing
- Intranasal Dexmedetomidine, Sublingual Dexmedetomidine
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Nourhan M.Aly
Conscious Sedation, Simple Lacerations Less Than 4 cm
A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department
The objective of this project is to compare the sedative effects of intranasal midazolam versus inhaled nitrous oxide (N2O) for minor procedures in the pediatric emergency department.
- Conditions
- Conscious Sedation, Simple Lacerations Less Than 4 cm, Lumbar Punctures, Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
- Trial name
- NCT03085563
- Testing
- Nitrous Oxide, Midazolam
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Colorado, Denver
Parathyroid Adenoma, Thyroid Nodule
The Feasibility of Bilateral Intermediate Cervical Plexus Block for Thyroidectomy/Parathyroidectomy
The aim of this study was evaluated the feasibility of bilateral intermediate cervical plexus blockade to be anesthesia for simple thyroid/parathyroid surgery.
- Trial name
- NCT04905641
- Testing
- Bilateral intermediate cervical plexus block
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
Dental Anxiety
Midazolam Sedation in Dentally Anxious Patients
Use lay language. To compare patient level of cooperation during dental care under conscious sedation with midazolam according to the administration route
- Trial name
- NCT01874717
- Testing
- Conscious sedation for dental care, midazolam
- Where
- France
- Volunteers
- 131 people
- Sponsor
- University Hospital, Clermont-Ferrand
Conscious Sedation
Current Procedural Sedation Practices in a Canadian Community Emergency Department
To review current Emergency Department procedural sedation practices in the community hospital setting and the associated drugs used (class of anesthetic and mode of administration).
- Trial name
- NCT04172415
- Testing
- Retrospective cohort
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Amber Graystone
Emphysema or COPD
Chartis Collateral Ventilation Measurement: Conscious Sedation Versus General Anesthesia
Rationale: The Chartis® ( Pulmonx, CA, USA) measurement system is a tool to assess interlobar collateral ventilation during bronchoscopy.
- Trial name
- NCT03205826
- Testing
- Type of sedation used
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Adrenal Insufficiency
Cortisol Response to Moderate and Deep Sedation in Children
Currently, it is unknown whether sedation itself induces a rise in serum cortisol levels or if cortisol levels rise under only the most invasive of procedures, regardless of the type of anesthetic agent used.
- Trial name
- NCT01265966
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Tripler Army Medical Center
Dental Caries, Child Behavior
Efficacy of Moderate Sedation for Dental Treatment of Young Children
There is lack of clinical trials on pediatric dental sedation. The purpose of this study is to test (using a randomized controlled trial design) the hypothesis that young children behavior during dental treatment improves with…
- Conditions
- Dental Caries, Child Behavior, Conscious Sedation Failure During Procedure
- Trial name
- NCT00902395
- Testing
- Midazolam, Protective stabilization, Midazolam, ketamine
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias