Clinical trials: Moderate Sedation
Atrial Fibrillation (Paroxysmal)
Safety and Efficacy of Conscious Sedation Versus General Anesthesia in Pulsed-Field Ablation for Paroxysmal Atrial Fibrillation
The goal of this clinical trial is to compare the safety and efficacy of conscious sedation and general anesthesia in patients with paroxysmal atrial fibrillation undergoing their first pulsed-field ablation (PFA) procedure.
- Trial name
- SEDATE-PFA (NCT07541339)
- Testing
- conscious sedation, General Anesthesia (control group)
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Beijing Anzhen Hospital
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork
Conscious Sedation
Efficiency of Ventilation During Conscious Sedation in the Pediatric Intensive Care Unit
Pediatric patients admitted to the intensive care unit and requiring conscious sedation for minor surgical procedures are at risk to hypoventilate and retain CO2. The rise in CO2 levels is not well described and unpredicted.
- Trial name
- NCT01287572
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Failed Conscious Sedation During Procedure
The Efficacy and the Safety of Dexmedetomidine Sedation on the Pediatric Intensive Unit(PICU) Patients.
To observe the efficacy and safety of dexmedetomidine sedation on the patients admitted to the pediatric intensive care unit after surgery.
- Trial name
- NCT02296073
- Testing
- Midazolam, Dexmedetomidine, Fentanyl
- Volunteers
- 120 people
- Sponsor
- Anhui Provincial Children's Hospital
Pregnancy, Abdominal, Termination of Pregnancy
TENS for Suction Evacuation for Termination of 1st Trimester Pregnancies
To study the effectiveness of the pain relief method of transcutaneous electrical nerve stimulation (TENS) for women who will undergo suction evacuation under conscious sedation for first trimester termination of pregnancy.
- Conditions
- Pregnancy, Abdominal, Termination of Pregnancy, Pain, Nerve
- Trial name
- NCT03494842
- Testing
- Transcutaneous nerve stimulation (TENS)
- Where
- Hong Kong
- Volunteers
- 170 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Conscious Sedation
Closed-loop Sedation of Propofol for Patients Undergoing Spinal Anesthesia
The purpose of this study is to compare the administration of a standard anesthetic drug (propofol) using an automatic, expert-based system versus a manually controlled system by the anesthesiologist.
- Trial name
- NCT01020643
- Testing
- controlled administration of propofol
- Where
- Canada
- Volunteers
- 203 people
- Sponsor
- Thomas Hemmerling
Conscious Sedation
Current Procedural Sedation Practices in a Canadian Community Emergency Department
To review current Emergency Department procedural sedation practices in the community hospital setting and the associated drugs used (class of anesthetic and mode of administration).
- Trial name
- NCT04172415
- Testing
- Retrospective cohort
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Amber Graystone
Cardiac Arrythmias, Anesthesia
Minimally Invasive Hemodynamic Monitoring in Cardiac Ablation
This prospective observational clinical study aims to evaluate the clinical utility of Pressure Recording Analytical Method (PRAM)-based minimally invasive hemodynamic monitoring in patients undergoing cardiac ablation…
- Trial name
- NCT07603765
- Testing
- Minimally invasive hemodynamic monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Istanbul University - Cerrahpasa
Conscious Sedation
Conscious Sedation for Cataract Operations Under Topical Anaesthesia
Topical anaesthesia of the eye for ophthalmologic procedures avoids pain and discomfort of local anaesthetic injection in the peribulbar or retrobulbar block so that patient comfortability is achieved.
- Trial name
- NCT03933280
- Testing
- Nalbuphine, Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Child Behavior, Dental Caries
Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment
Randomised clinical trial to test the efficacy, safety and cost-effectiveness of sedatives; masked, controlled, parallel design with three arms, phase 4.
- Trial name
- NASO (NCT02447289)
- Testing
- Intranasal ketamine, Oral ketamine, Intranasal midazolam
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Diagnostic Esophagogastroduodenoscopy
Alprazolam as Conscious Sedation for Upper Gastrointestinal Endoscopy
Diagnostic esophagogastroduodenoscopy is an uncomfortable and stressful procedure for most of the patients. Various methods are available for sedation during this procedure.
- Trial name
- NCT01949038
- Testing
- Oral alprazolam, Sublingual alprazolam
- Where
- Iran
- Volunteers
- 220 people
- Sponsor
- Isfahan University of Medical Sciences
Pain, Abortion
Diphenhydramine as an Adjunct to Moderate Sedation for Procedural First Trimester Abortions
This single center, double blind, randomized controlled trial will evaluate whether adding intravenous diphenhydramine to a standard moderate sedation regimen improves pain control during first trimester procedural abortion.
- Conditions
- Pain, Abortion, Anxiety
- Trial name
- NCT07542730
- Testing
- Diphenhydramine
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Rochester
Anesthesia, Spinal, Sedation, Conscious
Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
1. Adequate sedation with classical sedative agents, propofol 2. Sedation with propofol may induce paradoxical excitement response in heavy alcohol drinkers 3.
- Conditions
- Anesthesia, Spinal, Sedation, Conscious, Dexmedetomidine, Alcohol Drinking
- Trial name
- DEX (NCT02197403)
- Testing
- Dexmedetomidine, Propofol
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Chonnam National University Hospital
Kidney Calculi
Remifentanil in Extracorporeal Shock Wave Lithotripsy
The purpose of this study is to compare the analgesic efficacy and side effects induced by administration of two different infusion rates of remifentanil, 0,05 mcg/ Kg/ min versus 0,1mcg/ Kg/ min, in order to determine which one…
- Trial name
- ESWL (NCT01452880)
- Testing
- Remifentanil
- Where
- Italy
- Volunteers
- 228 people
- Sponsor
- University of Roma La Sapienza
Anesthesia, Psychomotor Status
Driving Skills Recovery Following Procedural Sedation for Gastrointestinal Endoscopy
This is a prospective cohort study that will analyze psychomotoric recovery using a commercially available driving simulator following sedation for endoscopic procedures in subjects undergoing elective outpatient endoscopic…
- Trial name
- NCT04350424
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Bronchoscopy, Sedation
Safety and Efficacy of Sufentanil Combined With Midazolam in Bronchoscopy Under Conscious Sedation: Retrospective Study
The aim of this study was to determine the safety and efficacy of sufentanil combined with midazolam in bronchoscopy under conscious sedation.
- Trial name
- NCT03890094
- Testing
- Sufentanil
- Where
- China
- Volunteers
- 11,158 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Moderate Sedation, Deep Sedation
Sedation and Neuromediators Concentration
Propofol (Propofol Kabi, Registration number from the State Register of Medicines - 000875) is a widely used intravenous anesthetic.
- Trial name
- NCT04695509
- Testing
- moderate propofol sedation (Bispectral index monitoring 70-90; The Richmond Agitation and Sedation scale (RASS) "-2" - "-3", deep propofol sedation (BIS 60-70, The Richmond Agitation and Sedation scale (RASS) "-4")
- Where
- Russia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Bronchoscopy, Conscious Sedation
Sedation During Bronchoscopy:Dexmedetomidine vs Alfentanil
The purpose of this study is to find the best sedation necessary for patients undergoing bronchoscopy. Patients are randomized to three different regimes of sedation during bronchoscopy were studied: 1.
- Trial name
- NCT01805726
- Testing
- xylocain, Alfentanil, Dexmedetomidine
- Where
- Lebanon
- Volunteers
- 162 people
- Sponsor
- Saint-Joseph University
Hypoxia, Apnea
Use of Capnography in EGD and Colonoscopy With Moderate Sedation.
This study will provide capnography monitoring during routine upper endoscopy and colonoscopy with moderate sedation in order to see if it improves safety.
- Conditions
- Hypoxia, Apnea, Hypotension, Hypopnea
- Trial name
- NCT01994785
- Testing
- Capnographic Monitoring
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- The Cleveland Clinic
Cataract
Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)
The investigators hypothesized that the combination of Valium, Tramadol and Zofran is superior to the substantially more expensive MKO melt in patient satisfaction after cataract surgery.
- Trial name
- NCT03653520
- Testing
- Diazepam, Tramadol, Ondansetron
- Where
- United States
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Avanti Anesthesia