Clinical trials: Modification
Large B Cell Lymphoma
Risk Adapted Therapy in Diffuse Large B Cell Lymphoma
This randomized phase II trial is studying two different combination chemotherapy regimens to compare how well they work in treating patients with diffuse large B-cell lymphoma.
- Trial name
- NCT03188198
- Testing
- rituximab, etoposide, cyclophosphamide, doxorubicin, vincristine,prednisone, filgrastim
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Urinary Bladder, Overactive
Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence
Pubovaginal sling (PVS) procedures are designed to curtail bladder leakage brought about by strenuous events such as child birth.
- Trial name
- NCT01194999
- Testing
- Pubovaginal sling procedure
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Barrie Urology Associates
Respiratory Tract Infections, Infections
Non-specific Effects of a Modified Measles Vaccination Schedule to Prevent Allergy and Unrelated Infection in Children
The goal of this clinical trial is to evaluate the off-target/non-specific effects of the measles-mumps-rubella (MMR) vaccine in children.
- Conditions
- Respiratory Tract Infections, Infections, Allergy, Eczema
- Trial name
- NEMAU (NCT05758532)
- Testing
- Measles-Mumps-Rubella vaccine (MMR)
- Where
- Switzerland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Laure Pittet, MD-PhD
Behavioral Symptom, Preschool Child
Cognitive-Based Behavior Change Training Program
This study will be conducted to determine the effects of the Parent Education Program Based on the Cognitive Development of the Child, which is applied to the parents of preschool children with behavioral problems, on the…
- Conditions
- Behavioral Symptom, Preschool Child, Parent, Parent-Child Relations
- Trial name
- NCT06985667
- Testing
- Cognitive-Based Behavior Change Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Uskudar University
Fever
Study of an App to Facilitate Communication With Parents of Febrile Infants
The objective of this research project is to test an evidence-based parent-centered care software application (e-Care) to ensure that parents of febrile infants from a wide range of socio-demographic backgrounds are optimally…
- Trial name
- NCT04328909
- Testing
- E-Care, Control Group
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Adolescent Idiopathic Scoliosis
Effect of VRGs on Changing the Center of Gravity Location in AIS
The purpose of this clinical trial is to examine the effect of virtual reality games (VRG) on changing the location of the center of gravity in children with adolescent idiopathic scoliosis (AIS).
- Trial name
- NCT05901792
- Testing
- Virtual Reality Games, Waiting List
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul University - Cerrahpasa
Hypothermia, Hyperthermia
Temperature Measurement in Surgical and Intensive Care Patients - Comparison of Four Measurement Methods
Comparison of four methods for measuring temperature perioperatively in patients scheduled for laparoscopic surgery and intensive care patients who are hypo-, normo-and hyper terme; Bladder Monitoring, Nasopharyngeal, SpotOn TM…
- Trial name
- Temp (NCT02220101)
- Where
- Norway
- Volunteers
- 95 people
- Sponsor
- Sykehuset i Vestfold HF
Obesity, Childhood, Type 2 Diabetes Mellitus in Obese
Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function
The investigators will measure blood levels of 1,5-anhydroglucitol in obese children with or without type 2 diabetes and correlate them with parameters related to functional beta-cell mass and glucose metabolism.
- Trial name
- NCT06682481
- Testing
- Measurement of biomarker
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Philippe Klee, MD-PhD
Uterine Fibroid
Design of an Intra-operative Blood Conservation Pathway at Open Myomectomy
Uterine fibroids are benign uterine masses that can be removed through a surgical procedure called a myomectomy. Myomectomy is often associated with a significant amount of blood loss for the patient.
- Trial name
- NCT03211481
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Unity Health Toronto
Asphyxia Neonatorum, Hypoxia
TOBY (TOtal Body hYpothermia): a Study of Treatment for Perinatal Asphyxia
Hypothesis: Prolonged whole body cooling in term infants with perinatal asphyxial encephalopathy reduces death and severe neurodevelopmental disability.
- Conditions
- Asphyxia Neonatorum, Hypoxia, Encephalopathy, Seizures
- Trial name
- NCT00147030
- Testing
- Whole body mild induced hypothermia
- Where
- United Kingdom
- Volunteers
- 325 people
- Sponsor
- Imperial College London
Bracket Failure, Bracket Bonding
Comparison of Bond Failure Rate of Orthodontic Brackets Bonded With V-Prep and Resin-Modified Glass Ionomer Cement Versus Conventional Acid-Etch Composite Resin
Ethical approval will be obtained by the FUSH and informed consent will be obtained from individual patients/guardians in writing.
- Conditions
- Bracket Failure, Bracket Bonding, RMGIC, Conventional Bracket Bonding
- Trial name
- NCT07828431
- Testing
- V-Prep and Resin-Modified Glass Ionomer Cement, Conventional Acid-Etch Composite Resin
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Hypothermia
Warming Mattress Versus Polyethylene Wrapping to Prevent Hypothermia in Preterm Newborns.
Mean axillary temperatures, taken during NICU resuscitation upon admission to the NICU, will not differ between VLBW babies who are occlusively wrapped and very low birth weight (VLBW) babies who are placed on thermal warming…
- Trial name
- NCT00603837
- Testing
- NeoWrap, InfaTherm
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
the Use of the Platform
An Analysis in the Use of Telecommunication Platform
The COVID-19 pandemic becomes a global challenge. Beneficial to being an island country and having appropriate policies, there were only few imported cases in Taiwan.
- Trial name
- NCT05597371
- Testing
- the use of the platform
- Where
- Taiwan
- Volunteers
- 1,000,000 people
- Sponsor
- National Taiwan University Hospital
Fever
Pilot Study Comparison Of Intravenous Ibuprofen And Intravenous Paracetamol In Management Of Pediatric Fever
Fever is one of the most common reasons children are brought to emergency departments. Treatment of fever with antipyretics is usually done simply to make children more comfortable, although in some circumstances, such as febrile…
- Trial name
- NCT04123717
- Testing
- Intravenous Ibuprofen
- Where
- Qatar
- Volunteers
- 147 people
- Sponsor
- Hamad Medical Corporation
Pre-Eclampsia
Measuring Practice Pattern Changes and Clinical Utility of a Novel Test for Preeclampsia
This study will collect high-quality data on how practicing obstetricians across the U.S. currently manage patients showing signs and/or symptoms of preeclampsia and how the results of Progenity's test change clinical decision…
- Trial name
- NCT04204018
- Testing
- Experimental Arm
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Glioma
The Role of Gene Changes in Brain Tumor Formation and Growth
This study will examine tissue from gliomas (a type of brain tumor) removed during surgery for gene mutations, or changes, thought to be involved in tumor formation and growth.
- Trial name
- NCT00059020
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dentin Caries
Evaluation of ART Restorations Using Two Different Bulk-Fill Restorative Materials in Primary Molars
The aim of this clinical study is to evaluate the success of two different bulk-fill restorative materials applied to teeth restored with atraumatic treatment at 3, 6, and 12-month follow-ups.
- Trial name
- NCT06771362
- Testing
- ART with Bulk-Fill composite, ART with Glass Ionomer
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Çanakkale Onsekiz Mart University
Underweight, Stunting
Evaluation Research of the Nutrition Interventions in the INHP II Areas of CARE India
This study is designed to evaluate the effectiveness of CARE India's Integrated Nutrition and Health Program (INHP II) to reduce malnutrition among children 0-23 months of age.
- Conditions
- Underweight, Stunting, Wasting, Anemia
- Trial name
- NCT00198835
- Testing
- Maternal nutrition and infant feeding advice
- Where
- India
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Microbial Colonization
Gut Microbiome Analysis in Organ Transplant Recipient
The microbiome acts as an antigen and can induce signaling through receptors like TLRs and NODs. Microbial metabolites can directly act on gut cells or reach other organs systemically.
- Trial name
- NCT06405958
- Testing
- gut microbiome
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Transgender, Transgender Persons, M01.777.500
Changes in Energy Expenditure (EE) in Transsexuals Undergoing Hormonal Therapy
Examining Metabolic Rate in Transgender individuals before starting hormonal treatment and 6-12 months after initiation
- Trial name
- NCT06733415
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
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