Clinical trials: Modification
Premature Birth
Changes in Respiratory Effort in Preterm Infants
Continuous Positive Airway Pressure (CPAP) is used to treat preterm infants with an immature respiratory center and having respiratory distress. CPAP requires intensive care monitoring and special qualified staff.
- Trial name
- NCT02014493
- Testing
- High Flow Nasal Cannulae (HFNC), Continuous Positive Airway Pressure (CPAP)
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- St. Olavs Hospital
Obesity, Childhood, Obesity
Mother-Baby Study - Observational
The rate of weight gain in the first year of life is risk factor for future obesity. The study will test (1) a model of l mechanisms underlying the development of emotion, attachment, and nutritive intake; and (2) the association…
- Trial name
- NCT06039878
- Testing
- Bonding-Evoked Oxytocin, Distress Relieving Effects of Sucrose, Hedonic Response to Sucrose
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cardiovascular Diseases, Heart Diseases
Genetic Epidemiology of Change in CVD Risk Factors
To extend knowledge of the genetic factors affecting the course of cardiovascular disease risk factor development over a substantial portion of an individual's lifetime.
- Trial name
- NCT00037440
- Testing
- Polymorphisms measured
- Volunteers
- 1,735 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Postural Balance
Balance Training Versus Traditional Physical Education in High School Students
This study will compare the effects of an 8-week balance-focused exercise program and traditional physical education on static and dynamic balance performance in high school students.
- Trial name
- NCT07805421
- Testing
- Balance-Focused Exercise Program, Traditional Physical Education
- Where
- Cyprus
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Human NiV Infection
Community Intervention to Prevent Nipah Spillover
Several human Nipah virus (NiV) outbreaks have occurred in Bangladesh since 2001with 71% case fatality. Outbreak investigations have repeatedly identified drinking fresh date palm sap as a risk factor for NiV transmission.
- Trial name
- NCT01811784
- Testing
- Ask people not to drink raw sap, Ask people not to drink sap or drink sap from skirt protected trees, No Intervention
- Where
- 4 sites in Bangladesh
- Volunteers
- 7,782 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Tuberculosis
Assessing Diagnostics At Point-of-care for Tuberculosis
Every year, more than 3 million people with TB remain undiagnosed and 1 million die. Better diagnostics are essential to reducing the enormous burden of TB worldwide.
- Trial name
- ADAPT (NCT05941052)
- Testing
- Tongue swab-based molecular assays
- Where
- 3 sites in Nigeria, Philippines and 1 more
- Volunteers
- 1,350 people
- Sponsor
- University of California, San Francisco
Psychological Distress
Practice-Based Evidence in Psychotherapy: A Multicentric Study From Ecuador
The goal of this observational study is to learn about the progress and outcomes of clients receiving psychotherapy for common mental health problems in Ecuador.
- Trial name
- CLIP_Ecuador (NCT07257848)
- Testing
- Psychological Intervention
- Where
- 11 sites in Ecuador
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Universidad de las Americas - Quito
Physiological Changes in Deliberate Apnea
Evaluating the Influence of Apnea on Cardiac Function Using Cardiac Magnetic Resonance Imaging.
Former studies revealed a distinct pattern of changes in circulation during deliberate apnea. Blood pressure rises significantly often accompanied by bradycardia.
- Trial name
- NCT02280226
- Testing
- magnetic resonance imaging (MRI)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Neonatal Morbidity, Neonatal Illnesses
Effect of Referral Card on Neonatal Medical Care Seeking for Institutional Births in Urban Lucknow
Neonatal mortality rate in Uttar Pradesh, Northern India is 53.6 per thousand, and accounts for 8% of global neonatal deaths.It has been argued that prompt and appropriate care-seeking for sick neonates can substantially reduce…
- Trial name
- Referral Card (NCT00832143)
- Testing
- Referral Card with one-to-one counseling
- Where
- India
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- King George's Medical University
Diabetic Retinopathy, Neurodegeneration
Retinal Neurodegenerative and Vascular Changes in Diabetic Patients
Using Optical Coherence Tomography and ImageJ software the investigators will analyze retinal and choroidal vascular changes and their impact on retinal layers among patients with diabetes without retinopathy and patients with…
- Trial name
- NCT04637217
- Testing
- Optical Coherence Tomography
- Where
- Romania
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Pediatric Obesity
Healthcare Text Messaging to Improve Diet, Physical Activity and Weight Loss in a Pediatric Lipid Clinic
The purpose of this study is to determine if health-related text messages sent from healthcare providers to overweight and obese adolescents enrolled at a pediatric lipid clinic will result in increased adherence to their…
- Trial name
- Text4Fit (NCT02228278)
- Testing
- Group A, Group B
- Where
- 3 sites in United States
- Volunteers
- 148 people
- Sponsor
- University of Florida
Metastatic Soft-tissue Sarcoma
T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.
To find a recommended dose of attIL2-TIL cell therapy that can be given to participant with either relapsed or metastatic sarcomas (has come back or spread to other parts of the body, respectively).
- Trial name
- NCT06474676
- Testing
- Cyclophosphamide, T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Athletic Performance
Acute Responses to a Potentiation Warm-up Protocol in Female Football Players.
This study aims to determine if the performance of female football players is affected after exposure to a potentiation protocol.
- Trial name
- NCT06555185
- Testing
- Potentiation warm-up protocol, Usual warm-up protocol
- Where
- Portugal
- Volunteers
- 17 people
- Sponsor
- University of Tromso
Underweight, Stunted Growth
Effects of Multiple-micronutrients Supplementation on Growth and Iron Status of Indigenous Children in Malaysia
Child undernutrition is largely attributed to inadequate nutrition including micronutrient deficiency. Undernutrition is prevalent among indigenous children as compared to the general population.
- Conditions
- Underweight, Stunted Growth, Wasting, Anemia
- Trial name
- NCT04561635
- Testing
- Multiple-micronutrients supplement
- Where
- Malaysia
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Spastic Hemiplegic Cerebral Palsy
Modified Constraint-Induced Movement Therapy in Children With Hemiparetic Cerebral Palsy
Cerebral palsy (CP) is defined as a non-progressive lesion of the developing foetal or infant brain and causes variety of motor, sensory and cognitive impairments.
- Trial name
- NCT04064788
- Testing
- Consecutive Modified Constraint-Induced Movement Therapy, Traditional physiotherapy, Intermittent Modified Constraint-Induced Movement Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Abant Izzet Baysal University
Juvenile Idiopathic Arthritis
Probiotic Treatment in Juvenile Idiopathic Arthritis (JIA)
This study investigates the efficacy of probiotic VSL#3 as an add on standard care on the activity of the disease in patients with Juvenile Idiopathic Arthritis.
- Trial name
- PERMAJI (NCT03092427)
- Testing
- VSL#3
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorders
Sensory Supported Swimming for Children With ASD
The purpose of Sensory Supported Swimming is to provide a sustainable, low cost recreational swim program for children with ASD.
- Trial name
- SSS (NCT02747459)
- Testing
- Sensory Supported Swimming
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- University of Kansas Medical Center
Autologous Blood Transfusion
Explore the Feasibility of Modified Blood Collection Method
Blood collection method: routine preparation according to predeposit autologous blood transfusion. Control group: according to the conventional blood collection method, the bevel of the needle head of the blood collection needle…
- Trial name
- NCT05539846
- Testing
- modified blood collection method
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University
Suicidal Ideation, Suicidal Behaviors
Pilot Study of a Modified Safety Planning Intervention for Elementary School-Aged Children - Main Study
The goal of this study is to finalize a version of the Safety Planning Intervention suitable for 6-12-year-old children. This intervention provides individuals with strategies to reduce the risk of suicidal behavior.
- Trial name
- NCT07564583
- Testing
- Child - Safety Planning Intervention, C-SPI+ecological momentary assessment
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Columbia University
Post Operative Pain
The Analgesic Efficacy of M-TAPA for Laparoscopic Abdominal Surgery in Children
This investigation aims to assess the efficacy of M-TAPA in children undergoing laparoscopic abdominal surgery. Sixty pediatric patients undergoing laparoscopic abdominal surgery under general anesthesia will be enrolled in this…
- Trial name
- M-TAPA (NCT07540689)
- Testing
- port site infiltration, M-TAPA
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
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