Clinical trials: Modification
Obesity, Childhood
Dissemination and Implementation of the Bright Bodies Intervention for Childhood Obesity
This study will evaluate the effectiveness of the Bright Bodies intervention in improving body mass index (BMI) among 7-13 year-old children with obesity simultaneously with the impact of the implementation strategy on adoption…
- Trial name
- NCT05595161
- Testing
- Bright Bodies
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- Yale University
Childhood Apraxia of Speech
Childhood Apraxia of Speech: Experience Dependent Changes Induced by Treatment
Childhood Apraxia of Speech (CAS) is a severe speech-language disorder whose aetiological, neuroanatomical correlates are largely unknown.
- Trial name
- CAS (NCT04832503)
- Testing
- PROMPT- treatment, LNSOM-treatment
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Fondazione Stella Maris
Prematurity
Effects of Massage Therapy and Kinesthetic Stimulation on Pre-Term Infants
The purpose of this study was to determine whether massage with or without physical exercise impacted weight gain or length of hospital stay for premature infants.
- Trial name
- NCT00661791
- Testing
- Massage therapy without exercise, Massage therapy with exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- George Washington University
Cleft Lip and Palate, Periodontal Pocket
Periodontal Changes Following Mid Maxillary Distraction
To evaluate the health status of the periodontium and dentition at the distraction osteogenesis site in CLP subjects using mid maxillary distraction (MMD).
- Conditions
- Cleft Lip and Palate, Periodontal Pocket, Attachment Loss, Periodontal
- Trial name
- NCT03686761
- Testing
- A Involvement with the osteotomy site of the surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
Autism Spectrum Disorder, Disruptive Behavior
RUBIES in Educational Settings
The proposed three-year pilot randomized trial aims to test the effectiveness of the newly-redesigned paraeducator-delivered RUBI for use in Educational Settings (RUBIES) intervention compared to usual care training in reducing…
- Trial name
- RUBIES (NCT05093686)
- Testing
- RUBIES, Usual Care Training
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Respiratory Distress Syndrome, Newborn
High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure for Respiratory Support of Preterm Neonates
This work is designed to: 1. Evaluate the efficacy of HHHFNC in comparison with nCPAP in preterm neonates. 2. Investigate hemodynamic changes associated with HHHFNC in comparison to nCPAP in preterm neonates during periods of…
- Trial name
- NCT04238273
- Testing
- Functional Echocardiography
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Ain Shams University
Coping Behavior, Mental Health Issue
The Changes of Coping With Stressful Events Among Adolescents Under the COVID-19 Pandemic.
This study aims to describe the changes in coping strategies used by adolescents for stressful life events under the background of epidemic normalization; and explore the causes of coping strategy changes of stressful life events…
- Trial name
- NCT05435469
- Testing
- Questionnaires
- Where
- China
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Dengue Fever With Warning Signs
Phase 3b Trial To Evaluate Safety And Immune Response (Superiority) of a Two-Dose Butantan-DV Regimen And The Standard Single Dose In Dengue-Naive Children/Adolescents and Immune Response (Non-inferiority) in a Manufacturing Facility Change (DEN-06-IB)
This randomized, double-blind, three parallel-group, multicenter, phase 3b trial evaluates the safety and immunogenicity of Butantan-DV. The study compares two primary immunization regimens (Butantan-DV/Butantan-DV vs.
- Trial name
- DEN-06-IB (NCT07712926)
- Testing
- Butantan-DV (IB), Butantan-DV (WuXi)
- Volunteers
- 1,765 people, healthy volunteers welcome
- Sponsor
- Butantan Institute
Stunting in Under-2 Children
Evaluating Bundling of Nutrition-specific Interventions
Background: 1. Burden: The prevalence of stunting among the under-five children in Bangladesh was >55% in 1997, which reduced to 41.9% in 2011.
- Trial name
- NCT02768181
- Testing
- Nutrition-specific Behaviour change communication (BCC), Nutrient supplement to pregnant women (PNS), Nutrienr supplement to children 6m to 2 years
- Where
- Bangladesh
- Volunteers
- 2,880 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Change in Bone Mineral Density, Bone Loss
LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
The primary objective of this study is to evaluate the impact of LF111 and drospirenone (DRSP) 3.5 mg chewable tablets on bone mineral density (BMD) at the lumbar spine after 12 months (13 medication cycles) of investigation in…
- Trial name
- NCT05303636
- Testing
- drospirenone 4 mg oral tablet or drospirenone 3.5 mg chewable tablet
- Where
- 37 sites in United States, Czechia and 1 more
- Volunteers
- 1,536 people, healthy volunteers welcome
- Sponsor
- Insud Pharma
Dental Pulp Disease, Dental Pain and Sensation Disorder
Comparison of Post Cementation Sensitivity Between RMGIC and GIC as Luting Materials in a Randomized Clinical Trial
This randomized controlled trial aims to compare post-cementation sensitivity between resin-modified glass ionomer cement (RMGIC) and conventional glass ionomer cement (GIC) as luting materials.
- Trial name
- RMGICvsGIC (NCT07102121)
- Testing
- luting material applaication with Modified Glass Ionomer Cement (RMGIC)
- Where
- Pakistan
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- Saidu College of Dentistry
Diabetes Mellitus, Diabetic Retinopathy
Study to Evaluate the Effectiveness of a Program Developed to Improve Eye Care for Veterans With Diabetes
The study's primary objective is to determine whether the PRSS improves the optimal timing of photocoagulation in diabetic patients in VA.
- Trial name
- NCT00119535
- Testing
- Implementation of Proactive Diabetes Eye Care Program
- Where
- 3 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- US Department of Veterans Affairs
Oral Health Behavior Change
The Effects of Two Volitional Interventions to Improve Oral Health Behaviour Among Iranian Adolescents
the present study had two main aims. First, due to the current underconsumption of dental brush adolescents, the investigators should apply a volitional intervention to increase oral health behvaiour in adolescents.
- Trial name
- NCT02066987
- Testing
- Implementation intention, Action planning, active control group
- Where
- Iran
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Qazvin University Of Medical Sciences
Complete Heart Block
PECs Block for Pacemaker Insertion in Children
Evaluation of Ultrasound Guided Modified Pectoral Nerves Blocks in Transvenous Subpectoral pacemaker insertion in Children: Randomized Controlled Trial
- Trial name
- NCT04931693
- Testing
- paracetamol, modifiedPECs block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Juvenile Rheumatoid Arthritis
Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid Arthritis
The primary objective of this study was to determine the efficacy of etanercept in pediatric patients with systemically active system onset juvenile rheumatoid arthritis (SOJRA).
- Trial name
- NCT00078806
- Testing
- Etanercept
- Volunteers
- 19 people
- Sponsor
- Amgen
Chronic Ankle Instability
Outcomes of the Modified-Brostrom Procedure Using Suture Anchor for Chronic Lateral Ankle Instability
This prospective, randomized study was conducted to compare the clinical outcomes of the modified Brostrom procedure using a suture anchor and bone tunnel for chronic lateral ankle instability.
- Trial name
- NCT01056055
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Chonbuk National University Hospital
Intracranial Hemorrhages, Prematurity
Neurophysiology and Anatomy of Severe Intraventricular Hemorrhage (IVH)
Currently, when premature infants develop severe intraventricular hemorrhage (IVH), a type of intracerebral bleed, there are no proven therapeutic interventions to prevent the devastating consequences of this event.
- Trial name
- NCT00817310
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University
Gastroesophageal Reflux
Pharmacokinetic and Safety of Dexlansoprazole in Adolescents With Gastroesophageal Reflux Disease
The purpose of this study is to asses the pharmacokinetics and safety of dexlansoprazole modified release (MR), once daily (QD), in adolescent subjects (age 12-17 years old) with Symptomatic Gastroesophageal Reflux Disease.
- Trial name
- NCT00847210
- Testing
- Dexlansoprazole MR
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Takeda
Obesity, Childhood, Pediatric Obesity
Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers
The US Preventive Services Task Force (USPSTF) recommends that providers screen children aged 6 years and older for obesity and offer or refer them to a comprehensive behavioral intervention (≥26 hours over a period of up to 12…
- Conditions
- Obesity, Childhood, Pediatric Obesity, Childhood Obesity, Adolescent Obesity
- Trial name
- TEAM UP (NCT03843424)
- Testing
- eSOC program, FBT program
- Where
- 7 sites in United States
- Volunteers
- 1,460 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Eating Disorder, Anorexia
Adaptive Treatment for Adolescent Anorexia Nervosa
The investigators are conducting a randomized controlled trial using an adaptive design for adolescents (ages 12-18) with anorexia nervosa to compare standard Family Based Treatment (FBT) to adaptive FBT with an Intensive…
- Conditions
- Eating Disorder, Anorexia, Anorexia Nervosa, Anorexia in Adolescence
- Trial name
- NCT03097874
- Testing
- Family Based Treatment, Family Based Treatment + Intensive Parental Coaching
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- Stanford University
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