Clinical trials: Mono
Dysmenorrhea
Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Primary Dysmenorrhea
The purpose of this study is to determine whether combination oral contraceptive pill of norethindrone and ethinyl estradiol is effective in the treatment of primary dysmenorrhea.
- Trial name
- NCT00746096
- Testing
- IKH-01
- Volunteers
- 115 people
- Sponsor
- Nobelpharma
Osteosarcoma
Monocyte Phenotypic and Functional Differences
The purpose of this study is to identify phenotypic (cell surface receptor expression) and functional differences in monocyte populations in humans with osteosarcoma as compared to published historical data on normal human…
- Trial name
- NCT02132182
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Ovulation Induction
A Prospective, Multi-centric Observational Study to Determine the Mono-bifollicular Development in Infertile Women Subjected to Ovulation Induction With Follitropin α
This is a prospective and multicentric observational study to determine the real mono-bifollicular development rate that is obtained under normal care conditions following ovulation induction (OI) treatment with follitropin-alpha…
- Trial name
- P450 (NCT01111084)
- Testing
- Follitropin alpha (r-FSH)
- Where
- Spain
- Volunteers
- 410 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Muscular Dystrophy, Duchenne Muscular Dystrophy
Study Safety and Efficacy of BMMNC for the Patient With Duchenne Muscular Dystrophy
This Study is single arm, single center trial to check the safety and efficacy of BMMNC (100 million per dose) for the patient with Duchenne Muscular Dystrophy,
- Trial name
- BMMNC (NCT01834040)
- Testing
- Intralesional/ Intravenous of Autologous Stem cells.
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chaitanya Hospital, Pune
HIV Disease
Evaluation of 3TC or FTC Mono-therapy Compared to Continuing HAART as a Bridging Strategy
The purpose of this study was to compare the use of lamivudine (3TC) or emtricitabine (FTC) alone vs. continuing a failing highly active antiretroviral therapy (HAART) regimen in HIV infected children, adolescents and young…
- Trial name
- P1094 (NCT01338025)
- Testing
- HAART regimen, 3TC or FTC monotherapy
- Where
- 17 sites in United States, Argentina and 3 more
- Volunteers
- 33 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Miniscrew Placement, Third Palatal Ruga
Miniscrews Placement for Orthodontic Anchorage
The goal of this retrospective observational mono-center study is to evaluate inter- and intra-operator variability and accuracy in miniscrews placement compared to CBCT-guided planning.
- Trial name
- NCT06635304
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS San Raffaele
STEMI
Monocytosis and Culprit Vessel in STEMI Patients
Increased white blood cell count at the onset of an acute ST elevation myocardial infarction has been shown to be associated of increased incidence of heart failure and mortality.
- Trial name
- NCT01569646
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Northwell Health
Nocturnal Enuresis
The Safety and Efficacy of Fluoxetine for Refractory Primary Mono-symptomatic Nocturnal Enuresis in Children
To determine whether there is a role for the selective serotonin reuptake inhibitors, fluoxetine, as therapy in the treatment of refractory primary monosymptomatic nocturnal enuresis in children , and whether there are side…
- Trial name
- NCT04676139
- Testing
- Fluoxetine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Severe Sepsis
Characterization of Non-canonical Way in Inflammasome Monocytes of Patients With Severe Sepsis
Activation of caspase-4 and human caspase-5 (orthologs of caspase-11 in mice) in innate immune cells.
- Trial name
- CASPASEs (NCT02539147)
- Testing
- blood samples
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Carcinoma
A Non Interventional Study With Paclitaxel Onkovis (Paclitaxel) Utilized for the Treatment of Cancer
The main purpose of this observational study with Paclitaxel is to determine the number of treatment cycles and the quantity of Paclitaxel onkovis needed therefore under the special circumstance of ambulant chemotherapy.
- Trial name
- NCT01668108
- Where
- 5 sites in Germany
- Volunteers
- 770 people
- Sponsor
- Onkovis GmbH
Carcinoma
A Non Interventional Study With Irinotecan Onkovis (Irinotecan) Utilized for the Treatment of Cancer
The main purpose of this observational study with Irinotecan onkovis is to determine the number of treatment cycles and the quantity of Irinotecan onkovis needed for this purpose under the special circumstances of ambulant…
- Trial name
- NCT01840280
- Where
- 5 sites in Germany
- Volunteers
- 324 people
- Sponsor
- Onkovis GmbH
Prostate Hyperplasia
The Effect of Pre-operative Use of Finasteride Versus Cyproterone Acetate on Blood Loss With Transurethral Resection of Prostate
Perioperative bleeding is the most common complication related to transurethral resection of prostate, the aim of the study is to compare the effect of pre-operative use of finasteride versus Cyproterone acetate on blood loss…
- Trial name
- NCT04848181
- Testing
- cyproterone acetate, finasteride, no treatment received
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Genetic Predisposition to Cancer
Single-institution Register of Individuals Undergoing Cancer Genetic Risk Assessment
Single-centre, retrospective, prospective observational cohort study, based on the registration of data from users of the Oncology Genetics Outpatient Clinic
- Trial name
- NCT06800599
- Where
- Italy
- Volunteers
- 7,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Healthy
Induction of Cytokines in Human Monocytes by SARS-CoV in Adults and Children
Severe acute respiratory syndrome (SARS) is a new emerging infectious disease. Its pathogen is a newly discovered coronavirus (SARS-CoV).
- Trial name
- NCT00173563
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Severe Acute Respiratory Syndrome
The Interaction Between Severe Acute Respiratory Distress Syndrome Viral Proteins and Monocytes
Severe acute respiratory syndrome (SARS) is a new threat to public health since November, 2002. The SARS is highly contagious and is believed to be transmitted by person-to-person through droplet and direct contact.
- Trial name
- NCT00172263
- Testing
- blood sampling
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Overweight, Obesity
Mono Unsaturated Fatty Acids in Obesity - Weight Maintenance and Prevention of Lifestyle Diseases in Obese Subjects.
The purpose of this study is to investigate the effect of three diets different in type and amount of fat in weight maintenance and prevention of life-style diseases in obese subjects.
- Trial name
- NCT00274729
- Testing
- Mono Unsaturated Fatty Acids in Obesity
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
Effect of Curodont Repair or Placebo on the Remineralisation in Patients With Class 5 Carious Lesions
The purpose of this study is to evaluate the therapeutic benefit of Curodont Repair for the treatment of early buccal carious lesions compared to placebo.
- Trial name
- NCT02020681
- Testing
- Curodont Repair, Fluoride
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Credentis AG
Alopecia Areata
Efficacy of Fractional CO2 Laser as a Mono- or Adjuvant Therapy for Alopecia Areata
Alopecia areata is a non-scarring hair loss disorder that affects both sexes equally. Incidence of the disease varies for different populations and in different studies, with global incidence ranging from 0.57% to 3.8%.
- Trial name
- NCT04003376
- Testing
- fractional carbon dioxide laser alone, Triamcinolone Acetonide 10mg/mL, platelet rich plasma
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Age Related Macular Degeneration
Survival of Monocytes Collected From Patients With Atrophic AMD in Retinal Pigmented Epithelium Explants
Age-related macular degeneration (AMD) affects 2 million people in France and is the main cause of irreversible blindness in France. All patients initially have an early form of the disease.
- Trial name
- SURViVOR (NCT04697095)
- Testing
- Blood samples
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Diphtheria, Pertussis
A Comparison of the Immunogenicity and Safety of Quinvaxem in Mono-dose Vials and Uniject
This is a study to show that vaccination with three doses of Quinvaxem presented in Uniject is not inferior to vaccination with three doses of Quinvaxem presented in single dose vials, with respect to protection against all…
- Conditions
- Diphtheria, Pertussis, Tetanus, Hepatitis B
- Trial name
- NCT01917357
- Testing
- Quinvaxem in Uniject, Quinvaxem in single dose vials
- Where
- Philippines
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Crucell Holland BV