Clinical trials: Morbidity
Postoperative Complications, Patient Care Team
Extended Care in High-Risk Surgical Patient (EXCARE) Pathway in High-risk Surgical Population
High risk surgical patients are subject to complications that impact rehabilitation time, overall mortality and costs. This project proposes the creation of a post-surgery care pathway called Extended Care in High-Risk Surgical…
- Trial name
- EXCARE (NCT04187664)
- Testing
- Postoperative Monitoring, High-sensitivity cardiac troponin testing
- Where
- Brazil
- Volunteers
- 1,720 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Newborn Morbidity
Impact of Explanation Given to Parents on Rate of Post-partum Influenza Vaccination
The aim of this study is to determine whether an explanation to parents for the need for post-partum influenza vaccination will influence their compliance.
- Trial name
- NCT03053674
- Testing
- Oral and written explanation, Follow-up questionnaire
- Where
- Israel
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Maternal Morbidity, Antenatal Health
Partnering With Antenatal Navigators to Transform Health in Pregnancy
The Partnering with Antenatal Navigators to Transform Health in Pregnancy (PATH) study aims to evaluate whether an antenatal patient navigation program improves maternal health, neonatal health, pregnant women's experiences, and…
- Conditions
- Maternal Morbidity, Antenatal Health, Neonatal Morbidity, Retention in Care
- Trial name
- PATH (NCT06941974)
- Testing
- Patient Navigation Program
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Northwestern University
Respiratory Morbidity
Inhaled Furosemide for Transient Tachypnea of Newborn
This is a randomized double blind clinical trial in which newborns with suspected Transient tachypnea of the newborn (TTN) will receive either furosemide or normal saline by nebulizer every 6 hours for 24 hours.
- Trial name
- NCT04397991
- Testing
- Furosemide
- Where
- Lebanon
- Volunteers
- 64 people
- Sponsor
- Makassed General Hospital
Hospital Adverse Event
Impact on the Adverse Event (AE) Incidence of Two Types of Experience Feedback on AE Analyzed During Local Morbidity Mortality Reviews
After implementing a French version of a trigger tool validated for computerized detection of adverse events in patient's medical record, the study will be performed in three parallel randomized arms of three identical…
- Trial name
- RMM Simulation (NCT02771613)
- Testing
- Multi professional in situ simulation, Large diffusion of information
- Where
- France
- Volunteers
- 144,000 people
- Sponsor
- Hospices Civils de Lyon
High-Risk Surgical Patients
A Therapy to Reduce Morbidity and Hospital Length of Stay of High-Risk Surgical Patients
Postoperative organ failures commonly occur after major abdominal surgery and substantially increase the utilization of resources and the costs of care, and are favored by tissue hypoxia.
- Trial name
- NCT00254150
- Testing
- Increase oxygen extraction rate
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Università Politecnica delle Marche
COVID-19
Validation of Prognostic Clinical Risk Scores in Predicting Outcome for Patients With COVID-19 at Initial Triage
Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causing Covid-19 pandemic continues to be a global health threat with a massive burden on health care systems resulting in more than six million deaths in…
- Trial name
- NCT05582382
- Testing
- logistic regression of known prognostic markers of severity of COVID19
- Where
- United Arab Emirates
- Volunteers
- 2,000 people
- Sponsor
- Dr Adnan Agha
Schistosomiasis
Health Benefits of Repeated Treatment in Pediatric Schistosomiasis
Objective and Hypotheses: This project has the overall objective of implementing and evaluating new approaches to reducing the current and future burden of urinary schistosomiasis in young children using the antihelminthic drug…
- Trial name
- NCT01424410
- Where
- Zimbabwe
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Malnutrition, Iron Deficiency
Impact of Sprinkles on Infectious Morbidity When Moderate to Severe Pediatric Malnutrition Is Highly Prevalent
The purpose of this study is to determine the safety profile of oral iron supplementation (OIS) with Sprinkles in a pediatric population with high prevalence of Iron deficiency (ID) and moderate or severe malnutrition (MSM); the…
- Trial name
- NCT00530374
- Testing
- Oral Iron Supplement
- Where
- Bangladesh
- Volunteers
- 268 people
- Sponsor
- The Hospital for Sick Children
Pulmonary Disease, Chronic Obstructive
Changes in Blood Gases, Disturbance of Breath During Sleep and Cardiovascular Co-morbidity in COPD Patients
Respiration failure type 2 is loss of the lungs ability to take up oxygen (O2) and get rid of carbon dioxide (CO2). The diagnosis is based on blood gas measurement of pressures of O2 and CO2.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Hypercapnia, Hypoxemia
- Trial name
- NCT00888342
- Testing
- supplementary oxygen, zopiclone, alcohol
- Where
- 2 sites in Norway
- Volunteers
- 150 people
- Sponsor
- LHL Helse
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Respiratory Complications
Respiratory Morbidity Among Children Who Were Born by Elective Cesarean Section After 37-38 Weeks vs. 39 Weeks and More
Background: It is known that after Cesarean section is correlated with respiratory complication more, if done after 37-38 week of gestation than if done after 39 weeks or more.
- Trial name
- NCT02060994
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 123 people
- Sponsor
- Hillel Yaffe Medical Center
Prematurity, Very Low Birth Weight
Impact of Sex and Own Mother's Milk Pasteurization on Morbidity and Mortality of Very Low Birth Weight Infants
In very low birth weight (<1500g) preterm infants, nutrition with mother's own milk, as opposed to formula, is associated with reduced morbidity and mortality.
- Trial name
- G-PAMINEO (NCT07411872)
- Where
- Germany
- Volunteers
- 900 people
- Sponsor
- Charite University, Berlin, Germany
Rare Diseases, Epidemiology
Verification of the Epidemiology and Mortality of Rare Diseases in Taiwan With Real-world Evidence
This study aims to explore the longitudinal incidence and prevalence trends of selected muscular and bone-related rare diseases, i.e., Familial Amyloidotic Polyneuropathy (FAP), Primary hyperoxaluria, Wilson's disease, Cystic…
- Conditions
- Rare Diseases, Epidemiology, Morbidity, Morality
- Trial name
- NCT05367115
- Testing
- longitudinal observational study
- Where
- Taiwan
- Volunteers
- 5,000 people
- Sponsor
- National Cheng-Kung University Hospital
Malnutrition, Stunting of Growth
Efficacy of Caterpillar Cereal for Complementary Feeding in the Democratic Republic of Congo
Two in every three infants in rural areas of the Democratic Republic of Congo (DRC) suffer from stunting of linear growth by 12 months of age.
- Conditions
- Malnutrition, Stunting of Growth, Iron Deficiency Anemia, Neurodevelopmental Impairment
- Trial name
- CAT02 (NCT01282788)
- Testing
- Caterpillar Cereal
- Where
- Republic of the Congo
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Sickle Cell Anaemia
Prevention Of Morbidity In Sickle Cell Disease Pilot Phase
The hypothesis is that in sickle cell anaemia, nocturnal oxyhaemoglobin desaturation, is associated with low processing speed index, and this morbidity can be reduced with overnight auto Continuous Positive Airways Pressure…
- Trial name
- NCT00415727
- Testing
- auto Continuous Positive Airways Pressure (CPAP) with oxygen supplementation
- Where
- 2 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- Institute of Child Health
Gastric Cancer, Mortality of Gastric Cancer
Predictive Factors of Morbidity and Mortality and Overall Survival of Patients With Gastric Cancer : a Case Series
This is a retrospective study extending over a period of three years concerning patients with gastric adenocarcinoma hospitalized in the digestive cancer surgery and liver transplant service of the IBN ROCHD University Hospital…
- Conditions
- Gastric Cancer, Mortality of Gastric Cancer, Overall Survival of Patients With Gastric Cancer
- Trial name
- NCT05186402
- Testing
- Total or subtotal gastrectomy
- Volunteers
- 80 people
- Sponsor
- Sylvestre KABURA
Failure of Cervical Dilatation, Complications; Cesarean Section
Is Routine Cervical Dilatation Necessary During Elective Caesarean Section? A Randomised Controlled Trial
The purpose of this prospective randomised study was to determine the effect of routine cervical dilatation during elective caesarean section on maternal morbidity
- Conditions
- Failure of Cervical Dilatation, Complications; Cesarean Section, Wound Infection,, External Causes of Morbidity and Mortality
- Trial name
- NCT01954719
- Testing
- cervix dilated after surgery, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Tuberculosis
Isoniazid Prophylaxis With Concomitant Cotrimoxazole in HIV-infected Children
The study involves use of isoniazid and cotrimoxazole as strategies for preventing infections in HIV-infected children and reducing mortality.
- Trial name
- NCT00330304
- Testing
- Isoniazid, Cotrimoxazole
- Where
- 2 sites in South Africa
- Volunteers
- 450 people
- Sponsor
- University of Cape Town
Measles Infection
Additional Measles Vaccine at 4 Months of Age
Overall objective: To conduct a randomised controlled trial (RCT) to examine whether an early two-dose measles vaccination (MV) strategy at 4 and 9 months will reduce child mortality compared with the WHO strategy of one dose of…
- Trial name
- NCT01486355
- Testing
- Measles vaccine
- Where
- Guinea-Bissau
- Sponsor
- Bandim Health Project