Clinical trials: Mothers
Malnutrition, Child
Community-based, Controlled, Open-label, Cluster-randomized Trial for the Reduction of Chronic Malnutrition in Children Under Two Years of Age, With Three Intervention Arms Grouped by Clusters, in Two Provinces in Southern Angola, Huíla and Cunene.
The severity of the stunting in the provinces of Huíla and Cunene, Angola, in children aged 6 to 59 months is considered to be very high, as defined by the World Health Organization (WHO) classification of 2018.
- Trial name
- NCT05571280
- Testing
- Nutritional Supplementation, Money transfers, Standard intervention
- Where
- 2 sites in Angola
- Volunteers
- 1,423 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Adolescents, 18 and Under When Child Was Born for Mothers
Young Parents Program, Project Connect
1. Specific Aims 1. To evaluate the effects of life skills/parenting groups that are embedded within a comprehensive multidisciplinary clinic for adolescent parents (the Young Parents Program), using a randomized control design.
- Conditions
- Adolescents, 18 and Under When Child Was Born for Mothers, 25 and Under When Child Was Born for Fathers
- Trial name
- YPPProCon (NCT01379924)
- Testing
- Parenting/Life Skills Intervention, Teen-tot medical home
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
HIV-1, HIV Infections
Safety and Immunogenicity Study of Candidate HIV-1 Vaccine Given to Healthy Infants Born to HIV-1/2-uninfected Mothers
Objectives: Safety and immunogenicity of MVA.HIVA vaccine in 20-week-old healthy Gambian infants born to HIV-1/2-uninfected mothers.
- Trial name
- PedVacc001 (NCT00982579)
- Testing
- MVA.HIVA
- Where
- The Gambia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
Neonatal Mortality, Maternal Mortality
Impact of New Tools of Simulation-enhanced Peer Learning on Neonatal and Maternal Mortality
In the vast majority of developing nations, frontline birth attendants are often the only care providers responsible for newborn care including newborn resuscitation, thermal care, feeding and administration of medications.
- Trial name
- Sim-II (NCT04904380)
- Testing
- Active peer learning
- Volunteers
- 3,456 people
- Sponsor
- Mbarara University of Science and Technology
Herpes Simplex
Herpevac Neonatal Substudy
The purpose of this study to look at the antibodies (proteins from the body's infection fighting system) in the blood of babies delivered by women who are participants in the Herpevac Trial for Women, and who were vaccinated with…
- Trial name
- NCT00138320
- Where
- 5 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Iron Deficiency Anaemia in Childbirth, Iron Deficiency
Maternal Iron Deficiency and Childhood Health
The aim of this prospective observational cohort study is to study maternal iron deficiency and iron deficiency anemia and the use of iron supplements in pregnancy and their impact on the health of the offspring and pregnancy…
- Conditions
- Iron Deficiency Anaemia in Childbirth, Iron Deficiency, Iron Deficiency in Pregnancy, Iron Deficiency Anemia in Pregnancy
- Trial name
- MATILDA (NCT06879080)
- Where
- Finland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Mothers of Newborn Infants
A Randomized Controlled Trial About Teaching Parents How to Manage Childhood Immunization Pain
There is no effect of a parent-directed fact sheet about pain management during childhood immunization and pre-test on parent learning about evidence-based pain relieving methods.
- Trial name
- NCT01637779
- Testing
- Fact sheet
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Toronto
Postpartum Depression
Postpartum Massage Therapy for Women and Infants: The Effect on Maternal Depression, Stress, Fatigue and Infant Temperament
Mother and infant massage, a type of complementary therapy, possesses the capacity to ameliorate maternal depression, stress, fatigue, and also infant temperaments and convert them into more manageable ones.
- Trial name
- NCT06377176
- Testing
- Massage therapy
- Where
- Indonesia
- Volunteers
- 102 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Gestational Diabetes Mellitus
Supporting American Indian/Alaska Native Mothers and Daughters in Reducing Gestational Diabetes Risk
The purpose of this study is to modify an existing Reproductive Health intervention for adolescents with diabetes for Gestational Diabetes and make it culturally appropriate American Indian/Alaska Native adolescents.
- Trial name
- NCT02723266
- Testing
- STOPPING-GDM
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of Pittsburgh
Gross Motor
The Hidden Burden of Cerebral Palsy: Exploring the Relationship Between Gross Motor Function of Children, Maternal Low Back Pain, and Quality of Life
Caregiving for cerebral palsy children covers a very wide range of activities such as heavy lifting and turning, bathing, helping the child to use the toilet, getting the child to sleep, dressing and assisting the transfer causes…
- Trial name
- cerebral palsy (NCT07919002)
- Testing
- gross motor group
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Respiratory Syncytial Virus, Respiratory Tract Diseases
Impact and Effectiveness of ABRYSVO® Vaccination During Pregnancy
This study will be conducted in collaboration with a research network of independent hospital sites to evaluate the vaccine effectiveness (VE) and impact of ABRYSVO vaccination during pregnancy in a real-world population over…
- Trial name
- BERNI (NCT06647654)
- Testing
- ABRYSVO
- Where
- Argentina
- Volunteers
- 1 people
- Sponsor
- Pfizer
ADHD, Parenting
Treating Parents With ADHD and Their Young Children Via Telehealth: A Hybrid Type I Effectiveness-Implementation Trial
This study will compare the effectiveness of combined parental stimulant medication and behavioral parent training (BPT) versus BPT alone on child ADHD-related impairment (primary outcome), child ADHD and externalizing symptoms…
- Trial name
- TPAC (NCT04240756)
- Testing
- Behavioral Parent Training, Extended release mixed amphetamine salts (MAS)
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- University of Maryland, College Park
Maternal Morbidity and Mortality, Stillbirth and Neonatal Mortality
Emergency Obstetric and Neonatal Care: The EmONC Trial
The objective of this cluster randomized controlled trial is to reduce maternal and neonatal mortality by increasing access to and improving the quality of obstetric and neonatal care for pregnant women in study clusters.
- Trial name
- EmONC (NCT01073488)
- Testing
- Community Mobilization, HBLSS and facility improvement
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 267,181 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Well-Being, Psychological
The Effect of Meditation on Resilience and Spiritual Well-Being Levels
Childhood cancers have become an important health problem with a rapidly increasing incidence. Although global and national data show that the developmental status of countries has an impact on the success of treatment, there is…
- Trial name
- NCT06484283
- Testing
- Meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
HIV (Human Immunodeficiency Virus)
Safe Generations Plus: Swaziland PMTCT LTF Study
This study is to understand how to improve retention in care and treatment services to HIV positive pregnant women and their babies in Swaziland.
- Trial name
- SG+ (NCT02969161)
- Where
- 10 sites in Eswatini
- Volunteers
- 616 people
- Sponsor
- Columbia University
Vaginal Infection, Breastmilk Collection
Evaluation of Breastmilk Microbiota as a Function for Immunity
The aim of this study is to evaluate the difference of breast milk microbiota between mothers with and without vaginal infections during pregnancy.
- Trial name
- NCT05005286
- Testing
- Past history of vaginal Infections
- Where
- Malaysia
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Emotion Regulation
Testing an Intergenerational Model of Suicide Risk in Mother-child Dyads
The investigators are interested in learning more about how the role of mothers' emotions has on the transmission of suicide risk to children.
- Trial name
- NCT06463054
- Testing
- Dialectical Behavior Therapy Skills Group Training, Safety Planning Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pittsburgh
Breast Milk Collection, Infant Development
Investigating Pathways Between Maternal Nutritional Status, Breastmilk Composition, and Infant Linear Growth in Rural Pakistan
Breastmilk is considered optimal for infant growth and development. However, evidence suggests that breastmilk composition can vary according to maternal nutritional status.
- Trial name
- NCT04451395
- Testing
- Multiple micronutrients (UNIMMAP composition)
- Where
- Pakistan
- Volunteers
- 196 people
- Sponsor
- Aga Khan University
Short Chain Fatty Acids Concentration in Breast Milk
Study on Short Chain Fatty Acids Concentration in Breast Milk and Its Correlation With the Maternal Diet
The purpose of this study is to determine whether the acetate, butyrate and propionate concentration in breast milk and to evaluate the possible correlation of these concentrations with maternal diet.
- Trial name
- NCT02301728
- Testing
- sampling of breast milk, obtaining information about the maternal diet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federico II University
Post Partum Hemorrhage
Effect of Delayed vs Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Spontaneous Vaginal Delivery
Policies for timing of cord clamping vary, with early cord clamping generally carried out in the first 60 seconds aLer birth, whereas latercord clamping usually involves clamping the umbilical cord greater than one minute after…
- Trial name
- NCT04353544
- Testing
- delayed cord clamping
- Where
- Italy
- Volunteers
- 122 people
- Sponsor
- Federico II University
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