Clinical trials: Motor Function
Spinal Muscular Atrophy (SMA)
Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials
This is a global, prospective, multi-center study that is designed to assess the long-term safety and efficacy of OAV101 in patients who participated in an OAV101 clinical trial.
- Trial name
- SPECTRUM (NCT05335876)
- Testing
- onasemnogene abeparvovec
- Where
- 32 sites in United States, Australia and 17 more
- Volunteers
- 20 people
- Sponsor
- Novartis Pharmaceuticals
Physical Functional Performance, Physical Education and Training/Methods
Strengthening Children's Coordination and Balance in Everyday Life
The World Health Organization recommends that children and teenagers aged 5 to 17 should be physically active for at least 60 minutes every day.
- Conditions
- Physical Functional Performance, Physical Education and Training/Methods, Postural Balance, Child
- Trial name
- KiKoBal (NCT07597720)
- Testing
- Exercise
- Where
- Austria
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences for Health Professions Upper Austria
Erbs Palsy
Electrical Stimulation on Erbs Palsy Infants
This study examined the effect of reciprocal electrical stimulation (RES) across elbow flexors and extensors on the reaction of degeneration percentage and motor function in Erbs palsy infants.
- Trial name
- RES (NCT06631664)
- Testing
- Traditional physical therapy, A computerized electrical stimulator (Vectra®2C; Chattanooga, TS, USA)
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Badr University
Duchenne Muscular Dystrophy (DMD)
Factors Influencing Physical Activity Levels in Children With Duchenne Muscular Dystrophy: An ICF-CY-Based Study
Duchenne Muscular Dystrophy (DMD) is a neuromuscular disease characterized not only by progressive muscle weakness but also by cognitive, behavioral, and psychosocial impairments.
- Trial name
- NCT07369609
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Cystic Fibrosis, Covid19
The Effects of Telerehabilitation on Muscle Function, Physical Activity and Sleep in Cystic Fibrosis During Pandemic
The aim of this study is to evaluate the peripheral muscle function, sleep disorders and physical activity level in children with cystic fibrosis who are physically inactive at home due to social isolation and to examine the…
- Conditions
- Cystic Fibrosis, Covid19, Social Isolation
- Trial name
- NCT04742049
- Testing
- Telerehabilitation-based, Follow-up based
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment
Vibration Effects on Gait and Balance in CP
This randomized controlled study aims to investigate the acute effects of local vibration applied to the spastic medial gastrocnemius muscle on balance and spatiotemporal gait parameters in children with hemiparetic cerebral…
- Trial name
- NCT07045519
- Testing
- Local Vibration Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kırıkkale University
Cerebral Palsy
Whole Body Vibration Effect on Trunk Control, Functional Performance and Selective Control
Permanent neurological disorders such as cerebral palsy lead to problems with motor, sensory, and cognitive functions, which in turn limit one's ability to do certain activities.
- Trial name
- NCT06461845
- Testing
- Whole Body Vibration group, conventional therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
School Readiness, Executive Function (Cognition)
Playful Physical Activity for Executive Functions and School Readiness in Preschool Children
Executive functions, such as attention, inhibition, working memory, and planning, are important for early learning and school readiness in preschool children.
- Conditions
- School Readiness, Executive Function (Cognition), Preschool Child Development
- Trial name
- PPA-EF-SR (NCT07678294)
- Testing
- Playful Physical Activities Intervention, Regular Physical Education Curriculum
- Where
- Tunisia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Inonu University
Executive Function
Comparison Between Plyometrics and Calisthenics on Executive Function in School Going Children
The goal of this clinical trial is to compare the effects of calisthenics and plyometric exercises on executive functions in school-going children.
- Trial name
- NCT06770192
- Testing
- Calisthenics, Plyometric, Control
- Where
- Pakistan
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cerebral Palsy
Effects of Virtual Reality Versus Motor Imagery in Children With Cerebral Palsy
Cerebral palsy is a neurodevelopmental disorder caused by brain injury that appears in infancy, children have mostly issues of gross motor functions, and activities of daily living.
- Trial name
- NCT06303440
- Testing
- Routine Physical Therapy+ Balance Training, Virtual Reality+ Routine Physical Therapy, Motor Imagery+ Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 63 people
- Sponsor
- Riphah International University
Bilateral Spastic Cerebral Palsy, Cerebral Palsy
Effect of Treadmill Gait Training Combined With Conventional Physiotherapy on Gait Performance and Functional Mobility in Children With Bilateral Spastic Cerebral Palsy: A Randomized Controlled Trial
Cerebral palsy is a neurological condition that affects movement, muscle control, and walking ability in children. Children with bilateral spastic cerebral palsy often experience increased muscle stiffness, difficulty with…
- Conditions
- Bilateral Spastic Cerebral Palsy, Cerebral Palsy, Spasticity Due to Cerebral Palsy, Gait Abnormality
- Trial name
- GAIT-CP (NCT07683338)
- Testing
- Treadmill Gait Training, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Syeda Khatoon e Jannat Welfare Foundation
Spastic Diplegic Cerebral Palsy
Effects of Core Stabilization Exercises on Postural Control in Spastic Diplegic CP Children
This randomized controlled trial will evaluate the effectiveness of a 12-week comprehensive core stabilization exercise program on balance, trunk control, and gross motor function in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07736417
- Testing
- Exercise, Conventional
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Shifa Tameer-e-Millat University
Spinal Muscular Atrophy
Responsiveness and Validation Study of MFM-32 in SMA Patients Treated With Nusinersen
The Motor Function Measure (MFM), a reliable tool assessing motor function and its progression in most neuromuscular diseases, is widely used in France in many teams.
- Trial name
- NusiMFM (NCT04602195)
- Where
- 10 sites in France
- Volunteers
- 33 people
- Sponsor
- Hospices Civils de Lyon
Developmental Dyslexia, Developmental Coordination Disorder
Functional MRI Study in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD)
All the studies underlined the high frequency of co-morbid associations in specific learning disorders. Understanding the reasons for these associations could enable us to determine the cerebral bases that underlie each disorder.
- Trial name
- FMRI-DCD-DD (NCT02393729)
- Testing
- Neuropsychological assessment, MRI Study
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Coronary Artery Disease
Effects of Exercise Training on Endothelial Function, Inflammation, Arterial Stiffness and Autonomic Function in CAD
The main purposes of this study is to analyze, in a randomized controlled trial, the effects of an exercise-based cardiac rehabilitation program (i) on biomarkers of endothelial function, (ii) on biomarkers of inflammation, (iii)…
- Trial name
- NCT01432639
- Testing
- Exercise-based cardiac rehabilitation program
- Where
- Portugal
- Volunteers
- 96 people
- Sponsor
- Universidade do Porto
Autism
Oxcarbazepine Versus Placebo in Childhood Autism
The proposed study is designed to assess the effectiveness of treatment with Oxcarbazepine vs. placebo in childhood/adolescent autism.
- Trial name
- NCT00467753
- Testing
- Oxcarbazepine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Binge Eating Behaviour, Eating Disorders
Biobehavioral Mechanisms of Activity and Loss of Control Eating in Children
Loss of control eating in children and adolescents is associated with a host of negative physical and psychological health outcomes and a prognostic marker for development of eating disorders.
- Conditions
- Binge Eating Behaviour, Eating Disorders, Physical Activity, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- NCT07823153
- Testing
- Go/No-go task, Visual food task, Emotion regulation task
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Cerebral Palsy, Motor Deficits
Constraint-Based Therapy to Improve Motor Function in Children With Cerebral Palsy
Pediatric Constraint-Induced (CI) Movement therapy is a rehabilitation program designed to improve motor function in children with partial paralysis.
- Trial name
- NCT00061139
- Testing
- Pediatric Constraint-Induced Movement therapy, Conventional pediatric motor rehabilitation therapy
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebral Palsy
Effects of Bobath Technique Versus Task Oriented Training on Gross Motor Function in Cerebral Palsy Children
Cerebral palsy is the most familiar motor disorder of childhood. Consistent with the results of recent scientific researches BOBATH approach in physical restoration of youngsters with cerebral palsy promotes formation of motor…
- Trial name
- NCT05123937
- Testing
- BOBATH technique, Task training
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Pregnancy, Preeclampsia
Influence of Physical Exercise on Endothelial Function in Pregnant Women
The purpose of this study is to determine the effect of regular aerobic exercise on endothelial function in pregnancy.
- Conditions
- Pregnancy, Preeclampsia, Exercise
- Trial name
- NCT00741312
- Testing
- Regular aerobic physical exercise, Activities of daily living
- Where
- Colombia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia