Clinical trials: Motor Function
Erb's Palsy
Effects of Modified Constraint-induced Movement Therapy With and Without Electrical Stimulation in Erb's Palsy
ERB's palsy is an injury of upper section of the brachial plexus (C5-6) leading to an internally rotated and adducted shoulder and a pronated forearm.
- Trial name
- NCT06303427
- Testing
- Modified constraint-induced movement therapy, Electrical stimulation
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Congenital Zika Syndrome
Impacts of a Physical Therapy Protocol on Motor Function in Children With Congenital Zika Syndrome
The study aims to evaluate the effects of a specialized physiotherapy protocol aimed at the motor function of children with Congenital Zika Virus Syndrome.
- Trial name
- NCT06900322
- Testing
- Experimental Group (stimuli and handling; physical therapy [PediaSuit]), control group (conventional physical therapy)
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- Gabriela Lopes Gama
Androgen Insensitivity Syndrome, Metabolic Parameters in AIS, CAIS, PAIS and MAIS
Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity
Background: Androgen effects in humans are usually (but not always) mediated by the androgen receptor which is coded for by the androgen receptor gene (AR gene).
- Conditions
- Androgen Insensitivity Syndrome, Metabolic Parameters in AIS, CAIS, PAIS and MAIS, Tumor Formation in AIS, CAIS, PAIS and MAIS, Sexual Function AIS, CAIS, PAIS and MAIS
- Trial name
- NCT04708431
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebrovascular Disorders, Healthy
Non-Invasive Electrical Stimulation of the Human Brain
This study is designed to allow researchers to use transelectrical stimulation to explore the function of the human nervous system and improve diagnosis of neurological disorders.
- Conditions
- Cerebrovascular Disorders, Healthy, Nervous System Diseases, Spinal Cord Injuries
- Trial name
- NCT00001216
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Nutrition Disorder, Child, Gross Motor Development Delay
Effect of a Nutritional Support System for Improving Gross Motor Function in Cerebral Palsy
Background: Most patients with cerebral palsy (CP) are dependent on parents due to the spasticity and limitations in their gross motor function.
- Conditions
- Nutrition Disorder, Child, Gross Motor Development Delay, Neuro: Cerebral Palsy, Diet Modification
- Trial name
- ENSSIGMCP (NCT03933709)
- Testing
- Nutritional Support System (NSS), deworming, recommended diet
- Volunteers
- 30 people
- Sponsor
- Anahuac University
Neuromuscular Diseases in Children, Respiratory Function Impaired
Respiratory Functions, Thoracoabdominal Movements and Exercise Capacity in Neuromuscular Diseases
The clinical trial titled "Investigation of Respiratory Functions, Thoracoabdominal Movements, and Exercise Capacity in Neuromuscular Diseases" aims to evaluate the respiratory functions, thoracoabdominal movements, and exercise…
- Conditions
- Neuromuscular Diseases in Children, Respiratory Function Impaired, Respiratory Insufficiency, Duchenne Muscular Dystrophy
- Trial name
- NCT06756633
- Testing
- Respiratory Function Test, Structured light plethysmography, 6 Minute Walking Test
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Motor Neuron Disease
Brain Function in Primary Lateral Sclerosis
This study will examine whether the motor cortex (the part of the brain that controls movement) works properly in patients with primary lateral sclerosis (PLS), a disorder in which voluntary movements are very slow.
- Trial name
- NCT00071435
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
fMRI Research, Transcranial Magnetic Stimilation
The Relationships Between Neural Correlates of Effort Perception and Physical Activity Engagement
Objectives and research hypothesis Physical inactivity is a major health concern that has been linked to a variety of chronic diseases, including obesity, diabetes, cancer, cardiovascular diseases, and mental disorders.
- Conditions
- fMRI Research, Transcranial Magnetic Stimilation, EEG Brain Oscillations, Motor Task
- Trial name
- EffortLESS (NCT06691490)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Esophageal Atresia, Healthy Children
Symptoms, Pulmonary Function, Muscle Strength, Exercise Capacity, and Frailty in Esophageal Atresia vs. Healthy Peers
Esophageal atresia is the most common congenital anomaly of the esophagus and is caused by abnormal development of the esophagus during intrauterine life.
- Trial name
- NCT06975982
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cerebral Palsy
Effects of Virtual Reality Versus Motor Imagery in Children With Cerebral Palsy
Cerebral palsy is a neurodevelopmental disorder caused by brain injury that appears in infancy, children have mostly issues of gross motor functions, and activities of daily living.
- Trial name
- NCT06303440
- Testing
- Routine Physical Therapy+ Balance Training, Virtual Reality+ Routine Physical Therapy, Motor Imagery+ Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 63 people
- Sponsor
- Riphah International University
Physical Activity, Obesity
The Impact of Activity Breaks on Cognitive Function, Adiposity and Fitness in Preschoolers
Project which objective is a) to test the effectiveness, in preschool children, of an integrated physical activity intervention in the classroom based on intervallic training (MOVI-HIIT) on improving executive function, body…
- Conditions
- Physical Activity, Obesity, Children, Cardiovascular
- Trial name
- MOVI-HIIT (NCT04863040)
- Testing
- MOVI intervention
- Where
- Spain
- Volunteers
- 522 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Obesity, Physical Activity
Associations of Cognition, Fitness, and Body Composition Among Ethnic Minority Youth
Cognitive Control is crucial for learning and development. This study examined the associations between cognitive control and physical fitness and body composition among ethnic minority children.
- Conditions
- Obesity, Physical Activity, Cognitive Function 1, Social
- Trial name
- NCT03342924
- Testing
- Flanker Test and physical fitness test
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of Miami
Diving, Aquatic
Effect of Diving and Aquatic Exercises on Muscle Spasticity and Motor Function in Children With Spastic Cerebral Palsy
This study aims to evaluate the effect of diving and aquatic exercises on muscle spasticity and motor function in children with spastic cerebral palsy.
- Conditions
- Diving, Aquatic, Muscle Spasticity, Motor Function
- Trial name
- NCT06902168
- Testing
- Intensive swimming program
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Benha University
Spastic Diplegia Cerebral Palsy
Comparative Effects of Under Water Exercise and Radial Extracorporeal Shockwave Therapy on Lower-Limb Spasticity, Gross Motor Function, and Quality of Life in Children With Spastic Diplegic Cerebral Palsy: A Randomized Controlled Trial
Children with spastic diplegic cerebral palsy often present with lower-limb spasticity, limited gross motor function, and reduced quality of life.
- Trial name
- spastic CP (NCT07878949)
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Emad Eldin Mohamed
Obesity, Childhood
Healthy Bodies Project to Prevent Childhood Obesity
The goal of this study is to evaluate components of a preschool-based intervention designed to (1) increase children's nutrition knowledge, (2) increase physical activity in childcare settings, (3) increase emotional, behavioral…
- Trial name
- Healthy Bodies (NCT04552678)
- Testing
- Healthy Eating, Active Play, Self-Regulation, Parent Education, Healthy Eating, Active Play, Self-Regulation, Healthy Eating, Active Play, Parent Education
- Volunteers
- 2,480 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cerebral Palsy
Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study
The study design is a single-subject ABA clinical trial that is investigating the feasibility including adherence, safety and tolerability of metformin in children aged 5 to 18 years with cerebral palsy (CP).
- Trial name
- NCT03710343
- Testing
- Metformin
- Where
- 2 sites in Canada
- Volunteers
- 3 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cancer
Physical Activity and Functioning in Palliative Cancer Patients - a Clinical Randomised Trial
The project consists of two studies where we want to throw light on the importance of physical activity/exercise to maintain physical function among cancer patients whose disease is not responsive to curative treatment.
- Trial name
- NCT00397774
- Testing
- Physical exercise, best supportive care
- Where
- 5 sites in Norway
- Volunteers
- 231 people
- Sponsor
- Norwegian University of Science and Technology
Cerebral Palsy (CP), Spastic Cerebral Palsy
Effect of Task Specific Electrical Stimulation on Upper Limb Gross Motor Skills in Children With Spastic Quadriplegia
Cerebral palsy is a non-progressive lesion of the brain occurring before 2 years of age resulting in disorders of posture and movement.( Ostensjo S, 2004)( Keles MN, 2018).
- Conditions
- Cerebral Palsy (CP), Spastic Cerebral Palsy, Quadriplegic Cerebral Palsy, Upper Limb Function
- Trial name
- NCT06925425
- Testing
- Task specific electrical stimulation ( TASES ), Designed Physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Glioblastoma, IDH-wildtype, Glioblastoma
The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
Resection of glioblastoma in or near functional brain tissue is challenging because of the proximity of important structures to the tumor site.
- Conditions
- Glioblastoma, IDH-wildtype, Glioblastoma, Glioblastoma Multiforme of Brain, Astrocytoma, Malignant
- Trial name
- RECMAP (NCT06273176)
- Testing
- Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia without mapping
- Where
- 8 sites in United States, Belgium and 3 more
- Volunteers
- 225 people
- Sponsor
- Erasmus Medical Center
Randomized Controlled Trial for Speech Disorders in Children
Treatment Efficacy for Developmental Motor Speech Disorders
The purpose of this study is to carry out a high-level treatment efficacy study on children with speech sound disorders with motor speech involvement (SSD-MSI) using a well-controlled Randomized Controlled Trial design.
- Trial name
- NCT02105402
- Testing
- PROMPT
- Where
- 3 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The Prompt Institute