Clinical trials: Motor Recovery
Cerebral Palsy, Hemiplegia
The Effect of Combined Armeospring and CIT on Neuro-motor and Functional Recovery in Children With Unilateral CP
The purpose of this study is to assess the use of a commercially available arm weight supporting training system (Armeo®Spring) in conjunction with Constraint Induced Therapy (CIT) for improving upper extremity function for…
- Conditions
- Cerebral Palsy, Hemiplegia, Upper Extremity Weakness
- Trial name
- NCT02914925
- Testing
- ArmeoSpring/CIT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St Mary's Hospital for Children
Perinatal Stroke
Baby Brain Recovery Study
This study will be a longitudinal multiple-visit observational study, done to identify possible bioindicators of recovery and repair of motor corticospinal pathways which may be targeted by future interventions in infants with…
- Trial name
- NCT05013736
- Testing
- Magnetic Resonance Imaging, Behavioral Assessments, Non invasive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Wisconsin, Madison
Hemiplegic Cerebral Palsy, Motor Activity
Action Observation Based Rehabilitation of Children With Unilateral Cerebral Palsy
Recent evidence suggested that Action Observation Therapy (AOT), based on observation of actions followed by immediate reproduction, could be a useful rehabilitative strategy for promoting functional recovery of children affected…
- Trial name
- NCT04088994
- Testing
- AOT Pathological Model Experimental Group, AOT Healthy Model Control Group
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Parma
Anesthesia Outcomes, Anesthesia Complication
Does Style of Pre-sedation Instructions Improve Patient Outcomes in Ambulatory Anesthesia for Oral and Maxillofacial Surgery?
This randomized controlled trial aims to evaluate the impact of a brief guided visualization exercise on anesthesia-related outcomes in oral and maxillofacial surgery in patients scheduled for ambulatory anesthesia in the oral…
- Conditions
- Anesthesia Outcomes, Anesthesia Complication, Anesthesia and Procedure Related Time Intervals, Anesthesia Recovery Period
- Trial name
- NCT06768021
- Testing
- Guided visualization and standardized pre-sedation instructions, Standardized pre-sedation instructions only
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Alameda Health System
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury
This study is to evaluate the use of a fully implanted device for providing hand function, reach, and trunk function to individuals with cervical spinal cord injury. Funding Sources: FDA OOPD NIH NINDS
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Spinal Cord Injury Cervical, Spinal Cord Injury at C5-C7 Level With Complete Lesion
- Trial name
- NNP-UE+T (NCT02329652)
- Testing
- Networked Neuroprosthetic System for Grasp and Trunk
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Anne Bryden
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Rett Syndrome
Technology-supported Motor Rehabilitation for People With Rett Syndrome
This study focuses on improving purposeful arm use while simultaneously reducing engagement in stereotypies. It is typically expected that the training period for this study will last about 6 months.
- Trial name
- TeMoRett (NCT07418905)
- Testing
- computer gaming
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Georgetown University
Rehabilitation of Upper Limb Motor Function in Hemiplegia Due to Supratentorial Cerebral Infarction Using Armeo Power Robot
Effects of Armeo Power Robot Therapy on Upper Limb Recovery in Hemiplegic Stroke Patients
This study investigates the effectiveness of combining Armeo Power robotic therapy with conventional rehabilitation techniques to improve upper limb motor function in patients with hemiplegia caused by supratentorial cerebral…
- Trial name
- BV108/RAPPHCN (NCT06708065)
- Testing
- Armeo Power robot restores upper limb motor function., A Home Exercise Program, Occupational therapy activities
- Where
- Vietnam
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
Cerebral Palsy (CP), Encephalitis
Effects of Combined Music Therapy and Occupational Therapy on Motor and Physiological Parameters in Children With Neurological Impairments: A Non-Randomized Controlled Trial
This study aims to explore the effects of an occupational therapy program combined with music therapy elements on children 5-12 years old with neurological disorders including those with neurogenic scoliosis.
- Conditions
- Cerebral Palsy (CP), Encephalitis, Brain Tumor (After Recovery)
- Trial name
- NCT07200687
- Testing
- Music therapy, occupational therapy
- Where
- Greece
- Volunteers
- 18 people
- Sponsor
- Armakola Filomeni
Chronic Obstructive Pulmonary Disease
The Effects of a Positive Expiratory Pressure (PEP) on Dyspnea and Dynamic Hyperinflation During Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients
From the relationship between pathophysiology of chronic obstructive pulmonary disease (COPD), dyspnea, and dynamic hyperinflation during ventilatory increasing, the investigators hypothesize that 1.
- Trial name
- NCT00741832
- Testing
- Conical Positive Expiratory Pressure Device (C-PEP), Control breathing
- Where
- Thailand
- Volunteers
- 11 people
- Sponsor
- Khon Kaen University
Stroke Patients, Stroke
Feasibility of a Physiotherapy Programme, With Integrated telerehabIlitation to Increase Rehabilitation Time and Improve Motor Function
About two thirds of people after stroke have some level of disability. Rehabilitation helps to reduce disability and supports people to return to a meaningful life.
- Trial name
- PRACTISE (NCT06871878)
- Testing
- PRACTISE Physiotherapy Intervention
- Where
- 4 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Glasgow Caledonian University
Fatigue, Physical Exercise
Associations Between Low Frequency Fatigue, Jump Height and Perceptual Measures of Muscle Soreness, Fatigue and Recovery
Over the recent years, the increased competitive demands in elite competitive athletes has sparked a heightened interest in monitoring fatigue. Given the nature of the soccer game, athletes may experience low-frequency fatigue.
- Trial name
- NCT06458166
- Testing
- Assessment of low frequency fatigue using low frequency eletrical stimulation
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Maia
Stroke
AdaptRehab imVR: Exploring the Feasibility of imVR for Upper Limb Stroke Rehabilitation in Ethiopia
Stroke is a major cause of long-term disability worldwide, particularly in low- and middle-income countries (LMICs). Upper limb impairments following stroke can substantially limit an individual's ability to perform daily…
- Trial name
- imVR (NCT07412899)
- Testing
- Virtual Reality Headset with immersive exercises.
- Where
- Ethiopia
- Volunteers
- 18 people
- Sponsor
- Jimma University
Concussion, Brain
Salivary Biomarkers for Concussion Recovery
The overarching purpose of this proposed research is to determine whether BDNF and/or specific miRNAs can serve as biomarkers for recovery from a concussion during prescribed exercise.
- Trial name
- NCT05379920
- Testing
- High Volume Aerobic Exercise, Low Volume Aerobic Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Cerebrovascular Accident, Paralysis
Motor Recovery in Recent Stroke Patients Treated With Amphetamine and Physical Therapy
The purpose of this study is to determine if giving amphetamines along with standard rehabilitation speeds motor recovery after a stroke.
- Trial name
- NCT00001783
- Testing
- 0-15 Water
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Spinal Cord Injury, Neuromodulation
Rehabilitation Combining Spatiotemporal Spinal Cord Stimulation and Real-time Triggering Exoskeleton After Spinal Cord Injury
Spinal cord injury (SCI) can be caused by trauma, inflammation, tumors, and other factors, often leading to issues such as impaired leg movement, abnormal sensation, and difficulties with bladder and bowel control.
- Conditions
- Spinal Cord Injury, Neuromodulation, Robot Assisted Gait Training
- Trial name
- SCS-EXS (NCT06881134)
- Testing
- SCS+EXS
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke Sequelae, Motor Skills Disorders
Cognitive-motor Training Post-stroke - a Pilot Randomized Controlled Trial
Stroke is a leading and growing cause of long-term adult disability. Up to 80% of stroke patients have impaired manual dexterity reducing their independence, return to work and quality of life.
- Trial name
- Cogmos (NCT06112574)
- Testing
- Visuomotor force control training
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Danderyd Hospital
Hemiplegia and/or Hemiparesis Following Stroke
The Effect of Good Limb Position Management Assistive Devices on Preventing Shoulder Subluxation in Hemiplegic Patients
Stroke is a leading cause of long-term disability worldwide. During the early stage of recovery after cerebral infarction, reduced muscle tone and muscle weakness in the affected upper limb may lead to shoulder instability and…
- Trial name
- NCT07675759
- Testing
- Commercially Available Shoulder Sling, Novel Shoulder Subluxation Prevention Orthosis
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Breast Cancer
PhysSurg-B : Physical Activity in Relation to Surgical Operations - Breast Cancer
The purpose of this study is to investigate whether a training program with intensified physical exercise prior to and after surgery for breast cancer enhances postoperative recovery.
- Trial name
- PhysSurg-B (NCT02560662)
- Testing
- Physical activity
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Vastra Gotaland Region
Anterior Cruciate Ligament Injury, Knee Injury
Optimizing Plyometric Training for Functional Recovery Post-ACL Reconstruction
While surgical anterior cruciate ligament reconstruction (ACLR) of the knee restores passive stability, studies are showing consistently poor long-term outcomes.
- Trial name
- NCT02148172
- Testing
- Standard Plyometric Training, Plyometric Training with BWS
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Montana