Clinical trials: Motor Recovery
Stroke
Effects of Cerebrolysin Combined With Rehabilitation on Motor Recovery in Stroke
This study, E-COMPASSII is a phase IV clinical trial designed as a multicenter, randomized, double-blind, placebo-controlled, parallel-group study. This study will enroll 80 subacute stroke patients with severe motor involvement.
- Trial name
- NCT02768571
- Testing
- Cerebrolysin
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Samsung Medical Center
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Post-partum, Women
Creatine for Recovery and Thinking in Mothers
The purpose of this randomized, double-blind, parallel-group trial is to compare the effects of two doses of creatine monohydrate (5 g/day versus 10 g/day) administered for four weeks in postpartum women.
- Trial name
- CREATE-MOM (NCT07795853)
- Testing
- Creatine Monohdyrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Ischemic Stroke
Remote Ischemic Conditioning for Motor Recovery After Acute Ischemic Stroke
The most recent treatment for stroke rehabilitation is to combine physical training with other therapies to enhance or accelerate recovery.The hypothesis of this study is that remote ischemic conditioning (RIC) might have a…
- Trial name
- NCT05263531
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ji Xunming,MD,PhD
Stroke, Sabacute Stroke
Bilateral Robot-assisted Upper Extremity Rehabilitation on Motor Recovery in People With Subacute Stroke
The goal of this clinical trial is to study the clinical effects of a robotic rehabilitation treatment through a bilateral exoskeleton (Bilateral Robot-Assisted Therapy-BRAT) during standard rehabilitation, on motor recovery…
- Trial name
- BILAX (NCT06906588)
- Testing
- Experimental, Control
- Where
- 3 sites in Italy
- Volunteers
- 70 people
- Sponsor
- IRCCS San Raffaele Roma
Healthy
Effects of Water-soluble Olive Extract Supplementation
Six weeks of supplementation of an olive extract will: Improve antioxidant status Reduce inflammation Reduce muscle damage Improve exercise performance Improve exercise recovery as compared to a placebo.
- Trial name
- NCT01113827
- Testing
- Olive Extract
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Osteoarthritis, Degenerative Joint Disease
The Study of Physical Activity Rewards After Knee Surgery
The objectives of this research are to conduct a proof of concept randomized controlled trial with 200 patients undergoing primary total knee replacement (TKR) at Brigham and Women's Hospital (BWH).
- Trial name
- SPARKS (NCT01970631)
- Testing
- Motivational Interviewing (MI), Financial Incentives
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Brigham and Women's Hospital
Acute Stroke
IMAS Optimization and Applicability in Acute and Subacute Stroke.
The investigator will investigate our Integrated sensor-based Motion Analysis Suite (IMAS) to objectively and quantitatively measure acute stroke patient motor status.
- Trial name
- NCT05469438
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Case Western Reserve University
Stroke, Chronic Stroke
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke.
- Conditions
- Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH)
- Trial name
- PHATHOM (NCT07053917)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Stroke, Ischemic, Healthy
Stochastic Resonance Stimulation in Brain Plasticity and Post Stroke Motor Recovery
This study evaluates the effectiveness of stochastic resonance electric stimulation on neuromuscular control and proprioception in healthy and individuals with stroke.
- Trial name
- NCT03839810
- Testing
- stochastic resonance electrical stimulation
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Stroke
Low-frequency Transcranial Magnetic Stimulation To Enhance Motor Recovery In The Subacute Phase After Stroke
Low-frequency repetitive transcranial magnetic stimulation (rTMS) of the unaffected hemisphere (UH) transiently improves motor function in patients in the chronic phase after stroke.
- Trial name
- NCT01333579
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Sao Paulo General Hospital
Stress, Health Knowledge, Attitudes, Practice
Mindfulness Meditation Versus Physical Exercise: Comparing Effects on Stress and Immunocompetence
The objective of this research project is to examine if including mindfulness meditation or physical exercise at lunch break improve workers' recovery from work stress.
- Trial name
- NCT03728062
- Testing
- Mindfulness meditation, Physical exercise
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Ictus, Severe Acquired Brain Injury
Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury
This study aims to evaluate the potential effects of premorbid personality on the short- and long-term global cognitive recovery in patients with severe acquired brain injury (sABI) or stroke.
- Conditions
- Ictus, Severe Acquired Brain Injury, sABI
- Trial name
- NCT07119827
- Testing
- Motor, cognitive and psychological assessment
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Universita di Verona
Stroke
Effects of Priming Intermittent Theta Burst Stimulation on Upper Limb Motor Recovery After Stroke: A Randomized Controlled Trial
The aim of this study is to investigate the effects of intermittent theta burst stimulation primed with continous theta burst stimulation (cTBS), on top of a standard robot-assisted training (RAT) on improving the upper limb…
- Trial name
- NCT04034069
- Testing
- Theta burst stimulation (TBS), Robot-assisted training
- Where
- Hong Kong
- Volunteers
- 42 people
- Sponsor
- The Hong Kong Polytechnic University
Exercise
Differences in Rate of Recovery Between Young and Middle-aged Men After Downhill Running
The aim of this study is to evaluate differences in rate of recovery between young and middle-aged men after prolonged (downhill) running.
- Trial name
- NCT04025723
- Testing
- Downhill running
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gepner Yftach
Colorectal Cancer, Colorectal Cancer Stage III
Multimodal Prehabilitation for Colorectal Surgery
Despite advances in surgical care, the incidence of postoperative complications and prolonged recovery following colorectal surgery remains high.
- Trial name
- NCT01356264
- Testing
- multimodal prehabilitation
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Stroke Sequelae, Motor Disorders
Clinical Validation of a Hybrid BCI-controlled FES for Upper Limb Rehabilitation After Stroke
The RECOMMENCER project aims at developing and testing a novel hybrid Brain Computer Interface device based on cortico-muscular connectivity, that will be employed to activate Functional Electrical Stimulation (FES) of upper limb…
- Trial name
- RECOMMENCER (NCT05511207)
- Testing
- RECOM - hBCI training, CTRL - upper limb training with FES
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Donatella Mattia
Stroke, Exercise
Addressing Arm Non-use by Encouraging Idle-time Activity During Early Recovery From Stroke
This project evaluates the feasibility of using custom wearable technology and associated procedures to increase activity of the more-involved upper extremity during the earliest stages of recovery from stroke by increasing the…
- Trial name
- NCT05900999
- Testing
- Feasibility of idle time exercise
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Marquette University
Dementia, Cognitive Dysfunction ( MMSE < 24 )
Animal-Assisted Therapy Combined With Standard Rehabilitation for Motor Recovery in Dementia Patients in a Medical and Rehabilitation Care Unit
The goal of this randomized study is to find out if animal-assisted therapy (AAT) - a structured program where trained animals take part in care sessions guided by health professionals - can help improve movement abilities in…
- Conditions
- Dementia, Cognitive Dysfunction ( MMSE < 24 ), Motor Skills Disorders
- Trial name
- RéMédi - A (NCT07730983)
- Testing
- Animal-Assisted Therapy, Standard psychomotor rehabilitation
- Where
- France
- Volunteers
- 32 people
- Sponsor
- LNA SANTE
Stroke, Cerebrovascular Accident
Fluoxetine Opens Window to Improve Motor Recovery After Stroke
The FLOW trial is a randomized placebo-controlled trial analyzing the effect of coupling an anti-depressant, fluoxetine (Prozac), and exercise to improve motor recovery following a stroke.
- Conditions
- Stroke, Cerebrovascular Accident, Cerebral Infarction, Brain Infarction
- Trial name
- FLOW (NCT03448159)
- Testing
- Fluoxetine Hydrochloride, Exercise Program
- Where
- 8 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto