Clinical trials: Movement Abnormalities
Tourette Syndrome in Adolescence, Tourette Syndrome
Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome
Investigators propose a cross-sectional, observational pilot study to examine the contribution of stress, family dynamics, and peer relationships to quality of life (QOL) in adolescents with Tourette syndrome (TS).
- Conditions
- Tourette Syndrome in Adolescence, Tourette Syndrome, Tourette Syndrome in Children
- Trial name
- InSPSCTS (NCT04449003)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Vanderbilt University Medical Center
Tourette Syndrome, Tourette Syndrome in Adolescence
A Study to Explore the Effect of Sepranolone in Tourette Syndrome
The study was an open-label, randomized, multicenter, parallel, Phase 2a study in adolescents and adult patients with Tourette syndrome that aimed to explore the efficacy of Sepranolone as a treatment for Tourette syndrome, by…
- Trial name
- NCT05434546
- Testing
- Sepranolone
- Where
- 2 sites in Denmark
- Volunteers
- 26 people
- Sponsor
- Asarina Pharma
Child Development Disorders, Pervasive
Using Mobile Technology to Reduce Stereotypy
Nearly all children with autism spectrum disorders engage in non-functional repetitive vocal and motor behaviours commonly referred to as stereotypy.
- Trial name
- NCT02124720
- Testing
- iSTIM
- Where
- 3 sites in Canada
- Volunteers
- 39 people
- Sponsor
- Université de Montréal
Wilson Disease
Study of Zinc for Wilson Disease
OBJECTIVES: I. Establish the safety and efficacy of extended maintenance zinc therapy in 200 patients with Wilson disease. II. Establish further the role of zinc in the prophylactic treatment of presymptomatic patients by…
- Trial name
- NCT00004338
- Testing
- zinc acetate
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Center for Research Resources (NCRR)
Autoimmune Disease, Mental Disorder
Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections
Bacteria carry substances on their surface called antigens. When antigens come into contact with the right kinds of cells in the body an immune reaction is caused.
- Conditions
- Autoimmune Disease, Mental Disorder, Obsessive Compulsive Disorder, Streptococcal Infection
- Trial name
- NCT00001658
- Testing
- Amoxicillin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Mental Health (NIMH)
Huntington Disease
Study of Huntington Patients in Connection With European Huntington's Disease Network (EHDN)
REGISTRY is a multi-centre, multi-national, prospective, observational study of Huntington's disease (HD) with a control group of volunteers.
- Trial name
- NCT01554033
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Parkinson's Disease, Sleep Disorder; Excessive Somnolence
Light Therapy Treatment in Parkinson's Disease Patients With Daytime Somnolence
Study objectives are to determine the efficacy, safety and tolerability of bright light treatment in Parkinson's Disease (PD) patients with daytime sleepiness.
- Trial name
- NCT01338649
- Testing
- Bright Light Treatment (Sun Ray Sunbox SB-558), Dim red light (Sun Ray Sunbox SB-558)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Northwestern University
Movement Disorder
Phenotype/Genotype Correlations in Movement Disorders
The goal of this protocol is to identify families with inherited movement disorders and evaluate disease manifestations to establish an accurate clinical diagnosis by using newest technological advances and investigate the…
- Trial name
- NCT00018889
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy, Infant Development
Associations Between General Movements Assessments and Cognitive Development
High risk infant is defined as infant with a negative history of environmental and biological factors, which can lead to neuromotor development problems.
- Conditions
- Cerebral Palsy, Infant Development, Cognitive Dysfunction, Cognitive Developmental Delay
- Trial name
- GMs (NCT05217056)
- Testing
- measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Inhalation Aromatherapy
Effect of Inhalation Aromatherapy on Anxiety and Depressive Symptoms of Geriatric Patients With Parkinson's Disease
The present study aims to: Investigate the effect of inhalation aromatherapy on anxiety and depressive symptoms of geriatric patients with Parkinson's disease.
- Trial name
- NCT05728177
- Testing
- Inhalation Aromatherapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Sydenham Chorea, Strep Throat
Dopaminergic Receptors in Sydenham's Chorea
Sydenham's chorea (SC) is a post-streptococcal, neuropsychiatric disorder associated with anti-neuronal antibodies. The investigators demonstrated elevated anti-D1-receptor (D1R) and anti-D2-receptor (D2R) antibodies titers…
- Trial name
- NCT04084977
- Testing
- Antibody detection
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center
Citrate Transporter Deficiency, Epilepsy
SLC13A5 Deficiency Natural History Study - Remote Only
SLC13A5 deficiency (Citrate Transporter Disorder, EIEE 25) is a rare genetic disorder with neurodevelopmental delays and seizure onset in the first few days of life.
- Conditions
- Citrate Transporter Deficiency, Epilepsy, Rare Diseases, Movement Disorders
- Trial name
- NCT04681781
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- TESS Research Foundation
Upper Extremity Dysfunction
Movement Enhancing Device for Children
The purpose of this study is to assess: 1) how infants move their bodies to explore, play, and solve problems, 2) if this is different in a high-risk group of infants, and 3) if these abilities can be advanced in a high-risk…
- Trial name
- NCT01959581
- Testing
- Movement Enhancing Device
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Parkinson Disease
Comparing the Effectiveness of Shotokan-Karate vs. Tai Chi on Balance and Quality of Life in Parkinson's Disease
The following study will be a comparison of balance and quality of life in Tai Chi training programs and Shotokan-Karate training programs in individuals with Parkinson's Disease.
- Trial name
- NCT03443752
- Testing
- Shotokan-Karate, Tai-Chi
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Parkinson Disease
Effect of Metformin as Add-on Therapy in Levodopa Treated Parkinson's Disease Patients
The goal of this clinical trial is to learn that metformin has effect on motor aspects of daily living and oxidative stress in levodopa treated Parkinson disease patients. Researcher will compare drug metformin to a placebo.
- Trial name
- NCT07055958
- Testing
- Metformin
- Where
- Bangladesh
- Volunteers
- 74 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Tourette's Syndrome
Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome
To evaluate whether supplementing with PS128 can improve the symptoms and quality of life related to Tourette's disease in children.
- Trial name
- NCT04805385
- Testing
- PS128
- Where
- Taiwan
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Wilson Disease, Generalized Epilepsy
Clinical Features and Outcome of Wilson's Disease With Generalized Epilepsy in Chinese Patients
Generalized epilepsy is rarely reported in patients with Wilson disease (WD) and lacks experience in clinical practice. We aim to provide better experience for the diagnosis and treatment for WD patients with epilepsy in the…
- Trial name
- NCT04965571
- Testing
- genetic test
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Neurodegenerative Diseases, Alzheimer Disease
Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study
In this retrospective register study, clinically classified individuals with neurodegenerative disease from the years 2010-2021 will be verified from the clinical records from KUH and Oulu University Hospital (OUH).
- Conditions
- Neurodegenerative Diseases, Alzheimer Disease, Frontotemporal Dementia, Lewy Body Disease
- Trial name
- DEGERWD (NCT06209515)
- Where
- Finland
- Volunteers
- 61,292 people
- Sponsor
- Kuopio University Hospital
Parkinson Disease
Conservative Iron Chelation as a Disease-modifying Strategy in Parkinson's Disease
This study evaluates the effect of iron chelation as a therapeutic strategy to slow the progression of Parkinson's disease. Half of participants will receive the deferiprone to 15 mg / kg twice daily morning and evening (30mg /…
- Trial name
- FAIRPARKII (NCT02655315)
- Testing
- Deferiprone
- Where
- 25 sites in Austria, Czechia and 6 more
- Volunteers
- 372 people
- Sponsor
- University Hospital, Lille
Parkinson Disease
Algorithm Guided DBS Programming in Parkinson's Patients
Patients undergoing Deep Brain Stimulation for Parkinson's disease will be subjected to standard of care programming and compared with the algorithm based programming (StimSearch).
- Trial name
- NCT06205043
- Testing
- StimSearch programming algorithm software, Clinician based programming
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Jaslok Hospital and Research Centre