Clinical trials: Movement Abnormalities
Wilson Disease
A Clinical Study to Evaluate the Safety and Efficacy of LY-M003 Injection in Patients With Wilson Disease
Wilson's disease (WD), also known as Wilson's disease, is a rare autosomal recessive metabolic disorder caused by a mutation of the copper transport ATPase β (ATP7B) gene located on the long arm of chromosome 13 (13q14.3).
- Trial name
- WD (NCT06650319)
- Testing
- LY-M003
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Chaohui Yu
Parkinson's Disease
A Long-Term Extension Trial From Late Phase II of SPM 962 in Advanced Parkinson's Disease Patients
The primary objective of this study is to investigate safety of SPM 962 in advanced PD patients in a multi-center, open-label, non-controlled study following once-daily multiple transdermal doses of SPM962 within a range of 4.5…
- Trial name
- NCT01631812
- Testing
- SPM 962
- Where
- 7 sites in Japan
- Volunteers
- 130 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Autistic Disorder
Citalopram for Children With Autism and Repetitive Behavior (STAART Study 1)
This study will determine the efficacy and safety of citalopram compared to placebo in the treatment of children with autism.
- Trial name
- NCT00086645
- Testing
- citalopram hydrobromide
- Where
- 6 sites in United States
- Volunteers
- 149 people
- Sponsor
- Boston University
Primary Dystonia, Hemifacial Spasm
Movement Disorder Survey in East China
Movement disorder involve recurring or constant muscle contractions causing squeezing or twisting movement, such as hemifacial spasm, blepharospasm, cervical dystonias etc.
- Trial name
- MDS (NCT01168388)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Sir Run Run Shaw Hospital
Parkinson Disease, Physical Inactivity
Physical Activity in Persons With Parkinson's Disease
Parkinson's disease (PD) is a leading neurodegenerative health condition in Sweden and a public health concern. Although no cure exists, functional independence and participation in society remain top priorities, and can be…
- Trial name
- ActivPARK (NCT06901869)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Tourette Syndrome
Brain Activity Associated With Tics in Patients With Tourette Syndrome
This study will examine brain activity associated with the involuntary urges or uncontrolled movements, called "tics," experienced by people who have Tourette syndrome (TS).
- Trial name
- NCT00141869
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Involuntary Movements
Pattern and Frequency of Non-epileptic Involuntary Movements
We will perform a medical record review of all patients seen in Assiut University hospital, Egypt, to determine the frequency of movement disorders seen, disease characteristics, diagnostic evaluations.
- Trial name
- NCT04083586
- Testing
- All investigations; laboratory and radiological, needed for diagnosis
- Where
- Egypt
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cerebral Palsy, Infant, Premature, Diseases
Associations Between Early Neonatal Neuroimaging, Hammersmith Infant Neurological Examination and General Movements
High risk infant is defined as infant with a negative history of environmental and biological factors, which can lead to neuromotor development problems.
- Conditions
- Cerebral Palsy, Infant, Premature, Diseases, Infant Development, Neurologic Disorder
- Trial name
- highrisk (NCT05217186)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Parkinson's Disease
The Long Term Impact of Initiating Pramipexole Versus Levodopa in Early Parkinson's Disease (CALM-PD Cohort Study)
To determine the long-term consequences (8 years) of initiating patients with Parkinson's disease on either pramipexole or levodopa.
- Trial name
- CALM-PD Cohort (NCT00804479)
- Testing
- No intervention.
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- University of Rochester
Parkinson Disease
Behavior Addictions Improvement in Parkinson Disease's Patients Treated by Subthalamic Stimulation : Long Term Follow-up
Improvement of behavioral addictions in STN-DBS in PD: Long term follow-up
- Trial name
- PDdicted (NCT01705418)
- Volunteers
- 69 people
- Sponsor
- University Hospital, Grenoble
Wilson's Disease
The Individual Therapy for Patients With Wilson's Disease
Based on the genotype characteristics and genotype-phenotype-treatment prognosis data of Chinese WD patients, this study intends to further optimize the treatment regimen of Chinese WD patients and formulate individualized…
- Trial name
- NCT03957720
- Testing
- DMPS, Penicillamine, DMSA
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Inherited Movement Disorders, Spinocerebellar Ataxias
Biomarker Research in Inherited Movement Disorders
Inherited movement disorders are rare conditions, whose cumulative prevalence are in the order of 5-10/100,000 inhabitants, in most cases progressive and can lead to a significant loss of autonomy after one or more decades of…
- Conditions
- Inherited Movement Disorders, Spinocerebellar Ataxias, Hyperkinetic Disorders
- Trial name
- BIOMOV (NCT05034172)
- Testing
- Clinical follow-up
- Where
- France
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson Disease, Parkinsons Disease With Dementia
A Pilot Study to Explore the Role of Gut Flora in Parkinson's Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding Parkinson's Disease.
- Conditions
- Parkinson Disease, Parkinsons Disease With Dementia, Parkinson-Dementia Syndrome, Parkinson Disease 2
- Trial name
- NCT04148326
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Parkinson's Disease
Motion Immune Magnetic Resonance Imaging (MRI)
The purpose of this study is to evaluate our recently developed MRI reconstruction strategy for producing artifact-free neuro and abdominal MRI data.
- Trial name
- NCT02302521
- Testing
- Multiplex Sensitivity Encoding (MUSE)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Duke University
Parkinson's Disease
Incidence of Parkinson's Disease Among Veterans
This is a database study. Medical records will be reviewed in order to document a new or pending diagnosis of Parkinson's disease and in order to learn more about the disease process.
- Trial name
- NCT00100438
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Tic Disorders
Acupuncture Treatment in Pediatric Patients With Tic Disorders: A Prospective, Single-Center, Randomized Controlled Trial
This study was conducted to observe the efficacy of Nourishing the vital energy and Regulating the spirit needle technique in the treatment of chronic tic disorder through the Yale Global Tic Severity Scale (YGTSS) and the…
- Trial name
- ATPTD (NCT07071428)
- Testing
- Regular acupuncture, the Nourishing the vital energyand Regulating the spirit needle technique
- Where
- China
- Volunteers
- 76 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Wilson Disease, D-Penicillamine
Wilson's Disease Treated With D-Penicillamine: Characterization of Skin Damage Secondary to Treatment by Measuring Skin Elasticity
Wilson's disease is a genetic disorder, resulting from an anomaly present on the ATP7B gene located on chromosome 13, causing a progressive accumulation of copper in various organs such as the liver, nervous system and cornea…
- Conditions
- Wilson Disease, D-Penicillamine, Effect of D-penicilline on Cutaneous Elastity of Wilson's Patient
- Trial name
- WILDERME (NCT06945081)
- Testing
- Preparation of forearm molds with SILFLO® silicone
- Where
- 2 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Parkinson Disease
Tolerability of Sifrol® in Ambulatory Patients Suffering From Parkinson's Disease
Study to obtain information about the co-operation of the different physician-colleagues in the treatment of patients with Parkinson's disease, both in private practices and clinics and about the primary treatment strategies in…
- Trial name
- NCT02248207
- Testing
- Pramipexole
- Volunteers
- 1,293 people
- Sponsor
- Boehringer Ingelheim
Tourette's Syndrome, Tourette's Disorder
Psychosocial Intervention for Young Children With Chronic Tics
Analysis of data from the recently completed NIH Child Comprehensive Behavioral Intervention for Tics (CBIT) study found a manualized behavioral treatment approach strongly superior to psychoeducation/supportive therapy for…
- Conditions
- Tourette's Syndrome, Tourette's Disorder, Tourette's Disease, Tourette Disorder
- Trial name
- CBIT JR (NCT03042507)
- Testing
- Comprehensive Behavioral Intervention for Tics (CBIT)
- Volunteers
- 15 people
- Sponsor
- Weill Medical College of Cornell University
Other Instability of Joint, Shoulder Region, Strain of Shoulder Muscle (Disorder)
The Effects of Muscle Characteristics on the Control of Shoulder Complex During Functional Movements
The movement control of shoulder joint relies not only on the glenohumeral joint, but also the critical contributions from scapulothoracic joint.
- Conditions
- Other Instability of Joint, Shoulder Region, Strain of Shoulder Muscle (Disorder), Movement Disorders
- Trial name
- NCT04176692
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tzu Chi University