Clinical trials: Movement Abnormalities
Movement Disorders, Treatment
High-tech Rehabilitation Impact on Muscle MRI
The use of high-tech techniques is becoming increasingly popular in the rehabilitation field, where the use of exoskeletons, robots, virtual reality, etc. allow for customized rehabilitation protocols.
- Trial name
- NCT06884956
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Eugenio Medea
Tourette Syndrome
Pramipexole Pilot Phase II Study in Children and Adolescents With Tourette Disorder According to DSM-IV Criteria
A randomized, double-blind, placebo-controlled, flexible dose study to evaluate efficacy and safety of Pramipexole versus placebo for 6 weeks in children (age 6-17) diagnosed with Tourette Disorder according to DSM IV criteria.
- Trial name
- NCT00558467
- Testing
- pramipexole immediate release (IR)
- Where
- 16 sites in United States, Germany
- Volunteers
- 63 people
- Sponsor
- Boehringer Ingelheim
Parkinson Disease, COVID
Evaluation of the Containment Impact Linked to the Covid-19 Pandemic in a Population of Parkinson Patients
The consequences of COVID-19 in these already fragile patients should be evaluated. It will be important to appreciate the confinement consequences imposed on the patient on the course and impact of the disease.
- Trial name
- ERCO-Park (NCT04466839)
- Testing
- Questionnaire and interview
- Where
- 8 sites in France
- Volunteers
- 411 people
- Sponsor
- University Hospital, Toulouse
Parkinson Disease
Precision Medical Diagnosis and Acupuncture Treatment for Parkinson's Disease
This study integrates traditional Chinese medicine syndromes and pulse diagnosis, and uses laser vibration overlay and functional cerebral angiography to understand the efficacy of scalp acupuncture against Parkinson's Disease.
- Trial name
- NCT03791983
- Testing
- Scalp Acupuncture, Body Acupenture
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Parkinson's Disease
The Effects of Dual Task Training in Individuals With Parkinson's Disease
The primary aim of the proposed project is to characterize dual tasking (DT) deficits to improve motor, cognitive, and quality of life outcomes in individuals with Parkinson's disease (PD).
- Trial name
- NCT02538029
- Testing
- Dual Task Group, Single Task Group
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Freezing of Gait, Parkinson Disease
Effects of Proprioceptive Focal Stimulation (EQUISTASI) on Freezing of Gait in Parkinson's Disease
Freezing of gait (FOG) is a common disabling condition in Parkinson's disease (PD), causes falls, and impairs quality of life. Therapeutic options for this symptom are limited and of limited efficacy.
- Trial name
- NCT03211260
- Testing
- EQUISTASI
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- ASST Gaetano Pini-CTO
Parkinson's Disease and Parkinsonism, Tai Chi
Seated Tai Chi Improves Dynamic Finger Pointing Task and Sitting Balance Control in Subjects With Parkinson's Disease
The goal of this prospective study is to investigate the effects of 3 months seated Tai Chi (TC) practice on the eye-hand coordination and sitting balance control of subjects with Parkinson's disease.
- Trial name
- NCT06928532
- Testing
- Seated TC
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- The Hong Kong Polytechnic University
Paediatric Patients
Markerless Motion Capture for 3D Clinical Gait Analysis (IMAGine)
Many children have trouble with walking and frequently trip and fall. To understand the extent of the changes in their walking, but also to inform and evaluate possible interventions to improve their walking, a gait analysis is…
- Trial name
- IMAGine (NCT07572214)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Parkinson Disease, Movement Disorders
Wearable Visual Cues in Parkinson's Disease
One of the most disabling features of Parkinson's disease (PD) is represented by the gait disturbances. Some systematic reviews and meta-analysis have showed that conventional physical therapy might improve gait as well as…
- Conditions
- Parkinson Disease, Movement Disorders, Gait Disorders, Neurologic
- Trial name
- NCT05478187
- Testing
- QWalk Study Group, Traditional visual cues - Control group
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Habilita, Ospedale di Sarnico
Primary Cervical Dystonia, DYT 1 Dystonia
Neuroimaging of Dystonia
The main purpose of this study is to investigate primary cervical dystonia as compared to healthy control subjects and DYT 1 dystonia as compared to healthy control subjects by examining cognitive measures, physical measures, and…
- Trial name
- NID (NCT02046447)
- Testing
- Primary Cervical Dystonia (Trihexyphenidyl), Controls Primary Cervical Dystonia (Trihexyphenidyl), DYT 1 Dystonia (Healthy Control)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Parkinson's Disease
The Effectiveness of Motor-motor and Motor-cognitive Dual-task Training Interventions on Balance in People With Parkinson's Disease: a Feasibility Study
This study aims to test the feasibility and acceptability of home-based motor-motor dual-task training and motor-cognitive dual-task training interventions, and balance-related outcome measures which may be used in an anticipated…
- Trial name
- NCT05710588
- Testing
- motor-motor dual-task training, motor-cognitive dual-task training
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Plymouth
Parkinson Disease, Dysphagia
6-year Follow-up of Dysphagia in Patients With Parkinson's Disease
We recruited 116 patients with idiopathic PD who were from the Neurology clinic of the Second Affiliated Hospital of Zhejiang University, School of Medicine from January 2014 to November 2014.
- Trial name
- NCT04928079
- Testing
- deep brain stimulation, Anti-Parkinsonian Drugs
- Volunteers
- 116 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Huntington Disease
Cooperative Huntington's Observational Research Trial
The purpose of this study is to collect prospective data from individuals who are part of a Huntington Disease (HD) family, in order to relate phenotypes between individuals and families with each other and genetic factors in…
- Trial name
- NCT00313495
- Where
- 52 sites in United States, Australia and 1 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- HP Therapeutics Foundation
Tourette Syndrome
A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's Disorder
The primary objective of this study is to evaluate the long-term safety and tolerability of ecopipam tablets in children (greater than or equal to [>=] 6 and less than [<] 12 years of age), adolescents (>=12 and <18 years of…
- Trial name
- NCT06021522
- Testing
- Ecopipam
- Where
- 67 sites in United States, Bulgaria and 6 more
- Volunteers
- 150 people
- Sponsor
- Emalex Biosciences Inc.
Tourette Syndrome
Safety, Pharmacokinetics, and Pharmacodynamics of NBI-98854 in Children and Adolescents With Tourette Syndrome
This is a Phase 1b, open-label, multiple-dose study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of NBI-98854 in a total of 36 pediatric subjects with Tourette syndrome (TS).
- Trial name
- T-FORCE (NCT02256475)
- Testing
- NBI-98854
- Where
- 10 sites in United States
- Volunteers
- 36 people
- Sponsor
- Neurocrine Biosciences
Parkinson Disease, Gait Disorders, Neurologic
Evaluation of Efficacy of Musical Treadmill in PD Rehabilitation
In order to evaluate the effectiveness of musical treadimll on gait parameters in patients with Parkinson's Disease, the investigators compare the outcome measures on two group of patients: one will undergo a 4-week daily musical…
- Conditions
- Parkinson Disease, Gait Disorders, Neurologic, Treadmill
- Trial name
- EMTPDR (NCT03546244)
- Testing
- musical treadmill, Traditional treadmill
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Parkinson Disease
Translation and Validation of BELA-p-K for QoL Evaluation in PD Patients
The BELA-P-k was translated from Dutch into Italian. Subsequently 102 patients with PD filled out the questionnaire
- Trial name
- NCT03073044
- Testing
- BELASTUNGSFRAGEBOGEN PARKINSON KURZVERSION (BELA-P-K)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Parkinson Disease
Chinese PD-LRRK2 Registry
The purpose of the Chinese PD-LRRK2 Registry(CPD-LRRK2R) is to develop a database of patients of Parkinson's disease with leucine-rich repeat kinase 2 (LRRK2) gene variants in mainland China.
- Trial name
- NCT03523104
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xiangya Hospital of Central South University
Dementia With Lewy Bodies
Terazosin for Dementia With Lewy Bodies
The TZ-DLB trial will be a 3:2 (active:placebo) randomized, double-blind, placebo-controlled Pilot trial to evaluate the tolerability of terazosin for the treatment of dementia with Lewy bodies.
- Trial name
- TZ-DLB (NCT04760860)
- Testing
- Terazosin Hydrochloride
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Qiang Zhang
Parkinson's Disease
Feasibility of a Trial Evaluating the Effectiveness of Occupational Therapy in Parkinson's Disease
The purpose of this study is to determine the feasibility of a RCT evaluating the effectiveness of occupational therapy in Parkinson's disease.
- Trial name
- OTiP pilot (NCT01010529)
- Testing
- occupational therapy
- Where
- 4 sites in Netherlands
- Volunteers
- 43 people
- Sponsor
- Radboud University Medical Center