Clinical trials: Movement Disorder
Infant Development, Preterm Birth
Auditory Environment by Parents of Preterm Infants
Data on parent-infant physical closeness and infants' auditory environment will be collected among preterm infants when they are at gestational age of 32 to 34 weeks.
- Conditions
- Infant Development, Preterm Birth, Language Development
- Trial name
- APPLE (NCT04826978)
- Testing
- Auditory environment
- Volunteers
- 116 people
- Sponsor
- Turku University Hospital
Cerebral Palsy
Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities
This study is investigating the potential effects of a high-intensity home-exercise program among children with cerebral palsy. The program includes rhythmic movements to music that are adapted for wheelchair uses and…
- Trial name
- NCT05619211
- Testing
- Sprint-Intensity Interval Training with Telecoaching
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Scoliosis; Adolescence
O-arm Assessment of Vertebral Movement Using ST2R Technique
The study is quantifying how the patients' back has been corrected using Medicrea's hardware through imaging taken before,during and after the surgery.
- Trial name
- NCT03609138
- Testing
- Spinal Hardware
- Sponsor
- Medicrea, USA Corp.
Cerebral Palsy, Infant Development
Relationship Between Prenatal Maternal Distress and the Quality of General Movements at 3 Months
Depression and anxiety symptoms are common during pregnancy which may disturb the intrauterine environment by affecting the mother's physiological responses to stress, and ultimately impair fetal and postnatal development.
- Conditions
- Cerebral Palsy, Infant Development, Maternal Distress
- Trial name
- NCT05694676
- Testing
- Assessment of the quality of Genaral Movements (GMs), State-Trait Anxiety Inventory-Trait, (STAI-T), Beck Depression Inventory, (BDI)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Karamanoğlu Mehmetbey University
Moderate and Severe Crowding in Lower Dental Arch
Evaluation of Effects of Bracket's Slot System on the Quantity and Quality of Teeth Movements During Orthodontic Leveling and Alignment Stage
Evaluation of effect of bracket slot system on the quality and quantity of tooth movement during leveling and alignment stage
- Trial name
- NCT05537506
- Testing
- Bracket slot 0.018, Bracket slot 0.022
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Nocturnal Hypokinesia, Parkinsons's Disease
Measuring the Effects of Continuous Dopaminergic Stimulation on Nocturnal Movements in Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disorder that is characterized with motor symptoms such as hypokinesia, rigidity, tremor and postural instability. These symptoms can also be present during the night.
- Conditions
- Nocturnal Hypokinesia, Parkinsons's Disease, Rotigotine
- Trial name
- NCT01554306
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Sleep Medicine Centre Kempenhaeghe
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
TicHelper: A Computerized Comprehensive Behavioral Intervention for Tics (CBIT)
Tic Disorders (including Tourette Disorder) are relatively common in school-age children and for some children can lead to significant psychosocial and physical impairment and diminished quality of life.
- Trial name
- NCT02413216
- Testing
- TicHelper, Internet Based Resources
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Utah
Parkinson Disease
Gender Differences in Parkinsonian Patients- a Swedish Register Study
BACKGROUND: The complex impact of gender has been studied in different perspectives of health and disease in the literature. However, few attempts have been made to compile data from systematic disease specific registrations…
- Trial name
- NCT04713306
- Where
- Sweden
- Volunteers
- 1,217 people
- Sponsor
- Region Jönköping County
Parkinson Disease
Help-seeking for Health Problems in People With Parkinson's
Non-motor symptoms (NMS) are common in Parkinson's disease (PD) and cause significant distress and decreased quality of life. A high rate of non-declaration of NMS by patients means that many NMS remain unrecognized and…
- Trial name
- PDHelp (NCT03275649)
- Testing
- Help-seeking for non-motor symptoms
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- City, University of London
Parkinson Disease
Sensory Stimulation Effect on Movement Speed in Patients With Parkinson Disease
Movement slowness (bradykinesia) is one of the main motor symptoms in Parkinson Disease (PD). Several studies have shown that patients with PD exhibit slowness because they are unable to modulate, in an optimal way, the velocity…
- Trial name
- NCT01544738
- Testing
- Aponeurotic stimulation (the diacutaneous fibrolysis method)
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- Université Libre de Bruxelles
Cerebral Palsy, Movement Disorders
Effects of Using Dynamic Elastomeric Fabric Orthoses
Purpose: The aim of this study was to investigate the effects of dynamic elastomeric fabric orthoses (DEFOs) used for lower trunk and pelvis on balance, gait parameters, and pelvis symmetry in children with cerebral palsy.
- Conditions
- Cerebral Palsy, Movement Disorders, Neurologic Disorder
- Trial name
- NCT04272398
- Testing
- dynamic elastomeric fabric orthoses
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Kırıkkale University
ADHD
Ongoing Tai Chi Training for Children With ADHD
Attention Deficit Hyperactivity Disorder (ADHD) has tremendous individual and societal impact, and the effectiveness of current standard treatments is limited.
- Trial name
- NCT03434509
- Testing
- Continuous Tai Chi and Mindful Movement classes
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Angelman Syndrome
A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7248824 in Participants With Angelman Syndrome (AS)
This is a phase I, multicenter, non-randomized, adaptive, open-label, multiple ascending, intra-participant, dose-escalation study with a long-term extension (LTE) part and an optional open-label extension (OOE) part.
- Trial name
- NCT04428281
- Testing
- RO7248824
- Where
- 12 sites in United States, Italy and 2 more
- Volunteers
- 74 people
- Sponsor
- Hoffmann-La Roche
Obsessive-Compulsive Disorder
Characterization of Childhood-Onset Obsessive-Compulsive Disorder
The purpose of this study is to learn more about Obsessive-compulsive Disorder (OCD) in children. OCD usually has a slow onset, and symptoms that may remain at a stable level over time.
- Trial name
- NCT00044239
- Where
- 4 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
PARKINSON DISEASE (Disorder), Multiple Sclerosis (MS) - Relapsing-remitting
Myrosinase Bioactivated Gglucoraphanin for the Treatment of Neurodegenerative Diseases (GRA-MYR-ND)
Glucosinolates (GLs) are phytocompounds mainly found in the Cruciferae (Brassicacea) and Moringa oleifera plants. The hydrolysis of GLs by myrosinase led to the production of isothiocyanate (ITCs).
- Conditions
- PARKINSON DISEASE (Disorder), Multiple Sclerosis (MS) - Relapsing-remitting, Pediatric Patients Affected by Neuromuscolar and Degenerative Diseases
- Trial name
- GRA-MYR-ND (NCT07360977)
- Testing
- bioactivated GRA for adult patients, bioactivated GRA for pediatric patients
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Choreatic Disorder
Heart and Skeletal Muscle Problems in Neuroacanthocytosis
The purpose of this study is to learn about heart and skeletal muscle problems related to neuroacanthocytosis (also called Mcleod's syndrome and Levine-Critchley disease).
- Trial name
- NCT00007228
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Collagen Degeneration
Type I Collagen Fragments in the GCF and Saliva During OTM
Investigate the levels of type I Collagen fragments ICTP and CTX in GCF and saliva during initial leveling and alignment of the teeth in a sample of adolescents undergoing orthodontic treatment.
- Trial name
- NCT05020431
- Testing
- Biological measuring of collagen fragments biomarker during orthodontic tooth movement
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dyskinetic Cerebral Palsy, Dystonic Cerebral Palsy
Cerebellar Deep Brain Stimulation for Movement Disorders in Cerebral Palsy in Children and Young Adults
The purpose of this study is to test the safety of placing Deep Brain Stimulators (DBS) in a part of the brain called the cerebellum and using electrical stimulation of that part of the brain to treat movement symptoms related to…
- Trial name
- NCT06122675
- Testing
- DBS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Cerebral Palsy
Kinesio Taping in Sit to Stand Movement fo Cerebral Palsy
Children with Cerebral Palsy (CP) present limited performance of functional activities and activities of daily life. Kinesio taping has been definied as a promising technique for children with CP ans has been extensively used in…
- Trial name
- NCT03403322
- Testing
- Kinesio taping, Without taping
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Universidade Federal de Santa Catarina
NGLY1 Deficiency
NGLY1 Natural History
N-glycanase 1 (NGLY1) Deficiency (OMIM #615273) is an ultra-rare, autosomal recessive disorder caused by loss of function variants in NGLY1 gene.
- Trial name
- NCT06122766
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Baylor College of Medicine
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