Clinical trials: Movement Disorders
Cerebral Palsy
Effects of CIMT With and Without MIT on Upper Limb of Children With Hemiparetic CP
Cerebral Palsy (CP) is a major cause of motor disability in children. Among these CP children, approximately one third have hemiparetic cerebral palsy.
- Trial name
- NCT06240988
- Testing
- Modified Constraint Induced Movement Therapy, Motor Imagery Technique
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Multiple Sclerosis
Evaluation of the Effect of Mental Imagery Training Combined With Modified Constraint-Induced Movement Therapy in Individuals With Multiple Sclerosis
This study aims to investigate the effects of mental imagery training combined with modified constraint-induced movement therapy in individuals with multiple sclerosis.
- Trial name
- NCT07899411
- Testing
- odified Constraint-Induced Movement Therapy + Mental Imagery Training, Modified Constraint-Induced Movement Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Hacettepe University
Childhood Onset Dystonias
Transcranial Direct-Current Stimulation in Childhood Dystonia
The investigators hypothesize that transcranial direct current stimulation over the motor cortex will reduce muscle overflow and improve hand function in children with primary or secondary dystonia.
- Trial name
- NCT01460771
- Testing
- TDCS (Transcranial Direct-current Stimulation)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Southern California
Movement Disorder
Human Movement Database
This study will collect information on the different ways people control limb and body movements. This information will be used to develop a database on normal movements and adaptive movements of people who have diseases that…
- Trial name
- NCT00001252
- Where
- United States
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Movement Disorders, Myoclonus
Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases
The purpose of this protocol is to identify families with inherited neurologic conditions, especially movement disorders, to evaluate affected and unaffected individuals clinically, and to obtain blood samples for genetic…
- Conditions
- Movement Disorders, Myoclonus, Nervous System Diseases, Tic Disorders
- Trial name
- NCT00001667
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease
Laser Shoes for Freezing in People With Parkinson's Disease
The purpose of this study is to assess the effectiveness of the visual cues of a wearable device in preventing freezing of gait (FOG) in those with PD.The aim is to investigate the impact of laser shoe attachments on gait in…
- Trial name
- NCT05131906
- Testing
- gait task and activity of daily living task
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Northern Arizona University
Premature Birth, Cerebral Palsy
Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants
This project focuses on motor development, muscle growth and muscle activity. Using advanced, instrumented tests such as , the link between muscles and the movement characteristics will be studied.
- Conditions
- Premature Birth, Cerebral Palsy, Neurodevelopmental Disorders, Brain Injuries
- Trial name
- BAMBI (NCT06111898)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Metastatic Brain Tumor, Primary Brain Tumor
Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System
The NeuroBlate® System (NBS) is a minimally invasive robotic laser thermotherapy tool that is being manufactured by Monteris Medical.
- Conditions
- Metastatic Brain Tumor, Primary Brain Tumor, Epileptic/Seizure Foci, Movement Disorders
- Trial name
- LAANTERN (NCT02392078)
- Testing
- NeuroBlate System
- Where
- 26 sites in United States
- Volunteers
- 1,153 people
- Sponsor
- Monteris Medical
Children With Disabilities
Feasibility Trial of Family-Centered Therapeutic Dance for Children With Disabilities
The primary aim of this exploratory cluster-randomized trial is to assess the feasibility and acceptability of delivering a school-based group therapeutic dance program through a family-centered approach for children with…
- Trial name
- DanceDiversity (NCT07166055)
- Testing
- Therapeutic dance
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Low Blood Pressure, Parkinsons Disease
The Effects of Nicotine Chewing Gum in Parkinson's Disease
The objective of this experiment is: To determine if nicotine chewing gum will improve acute episodes of orthostatic hypotension in PD subjects.
- Trial name
- PD (NCT02452125)
- Testing
- Nicotine gum
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York Institute of Technology
Teeth Mesial Drift, Bone Injury
Biological Anchorage With Selective Micro-osteoperforations (MOPs) in Canine Distalization
To evaluate the effect of selective micro-osteoperforations (MOPs) on the amount of distal movement of the upper canine, the mesio-distal inclination of the canine and the messiah movement of the upper first molar.
- Conditions
- Teeth Mesial Drift, Bone Injury, Orthodontic Pathological Resorption of External Root
- Trial name
- NCT03741504
- Testing
- micro-osteoperforations (MOPs)
- Where
- 2 sites in Colombia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
Tourette's Disorder
Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder (TD)
The goal of the current trial is to determine efficacy and safety of once-weekly aripiprazole in reducing Total Tic Severity (TTS) score in children and adolescents with Tourette's Disorder.
- Trial name
- NCT01418352
- Testing
- Aripiprazole
- Where
- 35 sites in United States, Bulgaria and 3 more
- Volunteers
- 83 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Parkinson's Disease, Epilepsy
Cohorts and Collections: Clinical and Genetic Study of Parkinson's Disease and Epilepsies
The DNA and Cell Bank of Instituts Federatifs de Recherche (IFR) of Neurosciences has been running for the last 15 years at the Institut National de la Santé Et de la Recherche Médicale (INSERM) Unit 679 (former unit 289).
- Trial name
- NCT00142363
- Where
- 15 sites in France
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Functional Movement Disorder
Study of the Ability of a New Technique to Effectively Diagnose Movement Disorders
Sante Fe is an investigation of a new technique to distinguish between different types of movement disorders, specifically organic versus functional, by observing changes in involuntary movements in two different situations.
- Trial name
- Sante-Fe (NCT03661021)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Parkinson Disease, Sexual Orientation
Perspectives on Healthcare Access and Equity of People With Parkinson's Disease Identifying as LGBTQ+
Study Rationale: Older adults who identify as lesbian, gay, bisexual, transgender, or queer (LGBTQ+) have worse health than non-LGBTQ+ older adults.
- Trial name
- LGBTQ+_PD (NCT05502055)
- Testing
- Individual interviews, Focus Groups, National Survey
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Creighton University
Tourette Syndrome
Ecopipam Tablets to Study Tourette's Syndrome in Children and Adolescents
This study evaluates the effect of ecopipam tablets in children and adolescents in the treatment of Tourette's Syndrome (TS). Half of the participants will receive ecopipam tablets, while the other half will receive matching…
- Trial name
- D1AMOND (NCT04007991)
- Testing
- Ecopipam
- Where
- 70 sites in United States, Canada and 3 more
- Volunteers
- 153 people
- Sponsor
- Emalex Biosciences Inc.
Brain Concussion, Mild Traumatic Brain Injury
The Role of Mechanical Diagnosis and Therapy in the Management of Concussion
The purpose of this study is to examine the role of a Mechanical Diagnosis and Therapy (MDT) examination in identifying participants diagnosed with concussion who display a directional preference compared to who don't display a…
- Trial name
- NCT05859815
- Testing
- Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- State University of New York at Buffalo
Psychological Adaptation, Parkinson's Disease
Stress-Busting Program for Caregivers of Patients With Neruological Diseases
Although family caregivers perform an incredibly valuable service for their relatives and the formal health care system, they do so at a considerable cost to themselves both emotionally and physically.
- Conditions
- Psychological Adaptation, Parkinson's Disease, Neurological Disorders
- Trial name
- NCT00122174
- Testing
- Stress Busting Program for family caregivers
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Parkinson's Disease
Motor Cortex Stimulation for Parkinson's Disease
Deep Brain Stimulation represents the golden standard for surgical treatment of Parkinson disease (PD), but it is not optimally effective for controlling every motor sign and adverse events are not so infrequent Therefore, other…
- Trial name
- NCT00637260
- Testing
- Motor cortex stimulation on., motor cortex stimulation off
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Catholic University, Italy
Healthy, Schizophrenia
Neuroimaging of Dopamine Metabolism in Normal and Psychiatric Patients
Brain cells communicate with each other by releasing chemicals called neurotransmitters. In order for brain cells to transfer information, one cell will release a neurotransmitter that will be recognized by a receptor located on…
- Trial name
- NCT00001320
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
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