Clinical trials: Movement Disorders in Children
Hemiplegia, Infantile
Movement in the Non-use of the Affected Upper Extremity in Children Hemiparesis: Mirror Therapy and Action-observation
Children with cerebral palsy hemiplegia present a restriction in the daily activities due to the limitation in the active movement of the affected upper extremity.
- Trial name
- NCT04284176
- Testing
- Mirror therapy and action-observation therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- CEU San Pablo University
Infantile Hemiplegia, Constraint Induced Movement Therapy
Intensive Therapies to Improve Manipulation in Young Children With Hemiparesis
mCIMT and BIT are therapies applied in children with hemiplegia which have a great evidence, but not in a early age. This research has the objective to know the effects of this therapies in infants diagnosed of infantile…
- Conditions
- Infantile Hemiplegia, Constraint Induced Movement Therapy, Family, Bimanual Intensive Therapy
- Trial name
- NCT06191588
- Testing
- INFANT CIMT/BIT
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- University of Seville
Movement Disorder
Cerebral Activity Related to Primary Motor Stereotypies in Children: An EEG Study.
Background: Motor stereotypies are a movement disorder characterized by involuntary, repetitive, and rhythmic movements. These movements have a predictable pattern and seem purposeful, but they serve no obvious function, tend to…
- Trial name
- NCT01037361
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Autism Spectrum Disorder (ASD
Monitoring Daily Mobility in Children With Autism
Children with autism spectrum disorder (ASD) often show motor abnormalities and sleep disturbances that affect behavior, learning, and family quality of life.
- Trial name
- SIMBA (NCT07519369)
- Testing
- placement of a wearable wrist sensor
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Acquired Brain Injury, Cerebral Palsy
Movement Improvement After Paediatric Armeo®Spring Rehabilitation
Children with acquired and congenital brain lesions (namely, cerebral palsy, CP, and acquired brain injury, ABI) may exhibit upper limb impairment, with consequent limitations in their daily living activities.
- Trial name
- NCT03552614
- Testing
- Upper limb robot-assisted rehabilitation, physiotherapy
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- IRCCS Eugenio Medea
Self-Perception, Body Weight
Effects of Active Video Games in Physically Inactive Children
Inactivity was reported to be high in children and considered to be the fourth common cause of death in all ages. The reason for children is usually the increasing indoor use of sedentary screen time.
- Trial name
- AVGAME (NCT03720938)
- Testing
- Active Video Games
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Tourette Syndrome
Alternatives for Reducing Tics in Tourette Syndrome (TS): A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Tourette Syndrome in Children and Adolescents
This is a study to evaluate the efficacy and safety of deutetrabenazine (TEV-50717) tablets for the reduction of motor and phonic tics associated with TS in children and adolescents 6 through 16 years of age.
- Trial name
- ARTISTS1 (NCT03452943)
- Testing
- TEV-50717
- Where
- 42 sites in United States, Canada and 4 more
- Volunteers
- 119 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Pediatric Disorder, Genetic Predisposition
Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy
This study looks at how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy. The study aims to understand how trihexyphenidyl is broken down and used in the body of pediatric patients and whether this…
- Conditions
- Pediatric Disorder, Genetic Predisposition, Dystonia, Secondary, Dystonia
- Trial name
- TRIKE2 (NCT06554288)
- Testing
- Trihexyphenidyl
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Mercy Hospital Kansas City
Cerebral Palsy
Mirror Therapy With Sensory Motor Training in Children With CP
The study compares two interventions in CP children: mirror therapy with sensory motor training versus mirror therapy with motor training.
- Trial name
- NCT06292416
- Testing
- Experimental: Mirror therapy with sensory motor training., Experimental: Mirror Therapy with motor training, Experimental: Motor Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Tourettes Disorder, Tourette Disorder
Expanded Access Program for Treatment With Ecopipam for Tourette's Disorder
The goal of this expanded access study is to learn about the long-term effects of Ecopipam in participants with Tourette's Disorder (TD).
- Trial name
- EBS-101-TD-392 (NCT07093541)
- Testing
- ecopipam HCl ~2mg/kg/day
- Where
- 26 sites in United States
- Sponsor
- Emalex Biosciences Inc.
Tic Disorders, Tourette Syndrome
Comparison of Keppra and Clonidine in the Treatment of Tics
The goal of this study is to confirm that levetiracetam has a better tic-suppressing profile than that of the widely used tic-suppressing medication, clonidine.
- Trial name
- NCT00370838
- Testing
- Levetiracetam, Clonidine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Harvey S. Singer
Mental Disorder Diagnosed in Childhood, Obsessive Compulsive Disorder
Preventive Measures for Childhood-Onset Obsessive-Compulsive Disorder and Tic Disorders (PANDAS Subgroup)
A subgroup of patients with childhood-onset obsessive-compulsive disorder (OCD) and/or tic disorders has been identified who share a common clinical course characterized by dramatic onset and symptom exacerbations following group…
- Conditions
- Mental Disorder Diagnosed in Childhood, Obsessive Compulsive Disorder, Streptococcal Infection, Tic Disorder
- Trial name
- NCT00001359
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Mental Health (NIMH)
Cerebral Palsy
Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.
Background: Cerebral palsy (CP) is the most common motor disorder that affects children. People with CP have weak muscles; they may have trouble controlling the movements of their arms and legs.
- Trial name
- NCT06498596
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Tourette's Disorder
Safety and Tolerability Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
The goal of the current trial is to obtain long term efficacy, safety and tolerability data of once weekly aripiprazole in children and adolescents with Tourette's Disorder.
- Trial name
- NCT01416441
- Testing
- Aripiprazole
- Where
- 80 sites in United States, Bulgaria and 8 more
- Volunteers
- 170 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Autism, Cerebral Palsy
Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG).
- Trial name
- NCT03434080
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cerebral Palsy Spastic Hemiplegic
Improving Hand Movements in Kids With One-Sided Arm Stiffness Cerebral Palsy Through Motion Minder Therapy (MoMT)
Motion Minder Therapy is a targeted intervention for fine motor skill challenges in spastic hemiplegic cerebral palsy children, emphasizing affordability, particularly in middle-income countries like India.
- Trial name
- MoMT (NCT06560281)
- Testing
- Motion Minder Therapy (MoMT)
- Where
- 2 sites in India
- Volunteers
- 10 people
- Sponsor
- Saveetha University
Tuberous Sclerosis, STXBP1 Encephalopathy With Epilepsy
Gait in Rare Diseases
The aim of this pilot study is to explore whether the knowledge and experience gained during the T-GaiD project (Treatment of Gait Disorders in Dravet Syndrome - NCT03857451) can be transferred to other populations with similar…
- Trial name
- GAGA (NCT05161494)
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- Universiteit Antwerpen
Attention Deficit Hyperactivity Disorder, Autistic Disorder
Characterization of Executive Functions and Patterns of Eye Movements in Children With Developmental Disabilities
The purpose of this study is to characterize the profile of executive functions and eye movements in several populations of children with developmental disabilities.
- Conditions
- Attention Deficit Hyperactivity Disorder, Autistic Disorder, Developmental Coordination Disorder
- Trial name
- NCT00716235
- Where
- Israel
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cardiac Disease, Respiratory Disease
Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)
Subjects will use the Gabi system on a daily basis for 3 months, each time the subject is resting or asleep. The Gabi system will recording the SpO2, pulse rate, respiratory rate and movements of the subject.
- Conditions
- Cardiac Disease, Respiratory Disease, Congenital Cardiac Defect, Cardiovascular Diseases
- Trial name
- BRIDGE (NCT05319236)
- Testing
- Gabi System
- Where
- 4 sites in United States, Belgium
- Volunteers
- 101 people
- Sponsor
- Gabi SmartCare
Cerebral Palsy, Excessive Crying
Excessive Crying in Children With Cerebral Palsy and Communication Deficits
Management of excessive crying in children with cerebral palsy and communication deficits [ECCCPCD] was guided by the associated clinical findings and investigations.
- Conditions
- Cerebral Palsy, Excessive Crying, Pain
- Trial name
- ECCCPCD (NCT04523935)
- Testing
- Baclofen, Diazepam, Clonazepam, Trihexyphenidyl, Tetrabenazine, Gabapentin, Topiramate, Lamotrigine, Amitriptyline.
- Volunteers
- 131 people
- Sponsor
- Sathbhavana Brain Clinic