Clinical trials: Movement Disorders in Children
Cerebral Palsy (CP)
Intensive Rehabilitation Program for Upper Limb in Children and Adolescents With Cerebral Palsy
Cerebral palsy is the most common motor disability in children. Individuals with CP often experience significant difficulties in the use of their upper limbs, which affects their autonomy and quality of life.
- Trial name
- NCT07285837
- Testing
- Intensive Rehabilitation
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Fondation Ellen Poidatz
Cerebral Palsy, Spastic, Rehabilitation
A Pilot Study of Constraint Induced Movement Therapy in Preschool Cerebral Palsy After Botulism Toxin Injection
To establish a pilot randomized, crossover study on applying 2 constraint-induced movement therapy (CIMT) interventions in children with hemiplegic cerebral palsy after botulinum toxin injection during preschool education.
- Trial name
- NCT04179682
- Testing
- 40-hour constraint-induced movement therapy
- Volunteers
- 6 people
- Sponsor
- Changhua Christian Hospital
Child Development Disorders, Pervasive
Using Mobile Technology to Reduce Stereotypy
Nearly all children with autism spectrum disorders engage in non-functional repetitive vocal and motor behaviours commonly referred to as stereotypy.
- Trial name
- NCT02124720
- Testing
- iSTIM
- Where
- 3 sites in Canada
- Volunteers
- 39 people
- Sponsor
- Université de Montréal
Cerebral Palsy (CP)
Constraint-induced Movement Therapy Combined With Functional Electrical Stimulation in Children With Cerebral Palsy
This randomized controlled trial aims to compare the effectiveness of Constraint-Induced Movement Therapy (CIMT) combined with Functional Electrical Stimulation (FES) versus CIMT alone in improving upper limb function, reducing…
- Trial name
- CIMT-FES-CP (NCT07587476)
- Testing
- Constraint-Induced Movement Therapy Combined with Functional Electrical Stimulation, Constraint-Induced Movement Therapy
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Montiha Azeem
Tourette Syndrome in Children, Food Intolerance
Peripheral Mechanisms of Humoral Immune Effector-mediated Tourette's Syndrome and the Role of Tuina Intervention
Tourette syndrome is a refractory type of tic disorder. Previous clinical studies have confirmed that Tuina has a good effect on TS, but the mechanism of action is still uncertain.
- Conditions
- Tourette Syndrome in Children, Food Intolerance, Inflammatory Response
- Trial name
- NCT06379373
- Testing
- Spine manipulation; westren medicine
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Spastic Hemiplegic Cerebral Palsy
Effectiveness of Modified Constraint-Induced Movement Therapy Versus Mirror Therapy in Spastic Hemiplegic Cerebral Palsy Children
This randomized controlled trial was conducted to compare the effectiveness of Modified Constraint-Induced Movement Therapy (MCIMT) and Mirror Therapy in improving upper limb function among children with spastic hemiplegic…
- Trial name
- NCT07747974
- Testing
- Experimental, Control
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Ibadat International University, Islamabad
Tourette Syndrome, Behavioral Problem
Parent Behavioral Training for Disruptive Behaviors in Tourette Syndrome
This is a randomized controlled trial to assess the efficacy of a parent training program to control disruptive behaviors in children with Tourette Syndrome.
- Trial name
- NCT02882490
- Testing
- Parent Training, Supportive Therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Clinic of Barcelona
Cerebral Palsy
Motor Imagery Training in Children With Unilateral Cerebral Palsy
Motor imagery (MI) is a promising method to improve more cognitive aspects of motor behaviour, and may, thus, be effective for facilitating motor planning in children with Cerebral Palsy (CP).
- Trial name
- NCT03954808
- Testing
- Motor Imagery Training, Traditional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Huntington's Disease
Child to Adult Neurodevelopment in Gene Expanded Huntington's Disease
Huntington's Disease (HD) is an autosomal dominant disease manifested in a triad of cognitive, psychiatric, and motor signs and symptoms. HD is caused by a triplet repeat (CAG)expansion in the gene Huntingtin (HTT).
- Trial name
- ChANGE HD (NCT01860339)
- Where
- 6 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Peggy C Nopoulos
Tic Disorders, Tics
Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics
The study will examine whether combining Comprehensive Behavioral Intervention for Tics (CBIT) with inhibition of the supplementary motor area (SMA) using transcranial magnetic stimulation (TMS) normalizes activity in the…
- Conditions
- Tic Disorders, Tics, Tic, Motor, Tic Disorder, Childhood
- Trial name
- NCT04578912
- Testing
- Comprehensive Behavioral Intervention for Tics (CBIT), Repetitive Transcranial Magnetic Stimulation (rTMS), Continuous Theta Burst Stimulation (cTBS)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Minnesota
Angelman Syndrome
REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome
The purpose of this study is to evaluate the efficacy and safety of obudanersen in children and adults with Angelman syndrome caused by a deletion or mutation of the UBE3A gene.
- Trial name
- NCT06914609
- Testing
- obudanersen
- Where
- 41 sites in United States, Australia and 10 more
- Volunteers
- 156 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Tourette's Disorder
Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
The goal of the current study is to determine efficacy and safety of once-weekly aripiprazole in reducing Total Tic Severity (TTS) score in children and adolescents with Tourette's Disorder.
- Trial name
- NCT01418339
- Testing
- Aripiprazole
- Where
- 39 sites in United States, Canada and 4 more
- Volunteers
- 135 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Autism, Autism Spectrum Disorder
Comparing Imitation and Stereotyped Behaviors in Autistic Children: Robots vs. Human Operators
Virtual QT is a social robot designed to interact with humans in social and educational contexts. Equipped with visual and vocal interfaces, the robot can recognize and respond to various human inputs, providing emotional support…
- Trial name
- NCT06144528
- Testing
- QT robot
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Tourette's Disorder
Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder (TD)
The goal of the current trial is to determine efficacy and safety of once-weekly aripiprazole in reducing Total Tic Severity (TTS) score in children and adolescents with Tourette's Disorder.
- Trial name
- NCT01418352
- Testing
- Aripiprazole
- Where
- 35 sites in United States, Bulgaria and 3 more
- Volunteers
- 83 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Tourette's Syndrome, Tic Disorders
Open Label Trial of Aripiprazole in Children and Adolescents With Tourette's Disorder
The purpose of this study is to determine if Abilify will reduce tics (repetitive, uncontrollable movements or vocalizations) in children and adolescents ages 7-18 with Tourette's Disorder (TD) or a chronic motor tic disorder…
- Trial name
- NCT00241176
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- NYU Langone Health
Hemiplegic Cerebral Palsy
Bimanual Task Training and Constraint-Induced Movement Therapy in Hemiplegic Cerebral Palsy Children
Various studies have been done comparing the individual effects of the two interventions of Constraint-Induced Movement Therapy and Bimanual Task Training in Hemiplegic Cerebral Palsy Children, but this study will compare the…
- Trial name
- NCT05380011
- Testing
- Constraint Induced Movement Therapy and Bimanual Task Training, Bimanual Task Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Tourette Syndrome, Tourette's Disorder
Assessment of Children With Tic Onset in the Past 6 Months
The purpose of this research is to study why most children who have tics never develop Tourette syndrome but some do. In other words, we aim to find features that may predict whose tics will go away and whose tics will continue…
- Conditions
- Tourette Syndrome, Tourette's Disorder, Chronic Motor or Vocal Tic Disorder, Transient Tic Disorder
- Trial name
- NewTics (NCT01177774)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Washington University School of Medicine
Developmental Coordination Disorder
Kinesio Taping and Physiotherapeutic Exercises for Children With DCD
Aim: To investigate the effectiveness of a novel elastic taping-augmented functional movement power training (KT-FMPT) program in improving leg muscular performance, body balance, motor proficiency and functional independence in…
- Trial name
- NCT04123912
- Testing
- Kinesio Taping - Functional Movement Power Training
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Chronic Tic Disorder
Group Therapy Versus Individual Therapy for Tourette Syndrome and Chronic Tic Disorder
Chronic tic disorder (CTD) may have a huge impact on life quality. Habit Reversal Training (HRT) and Exposure Response Prevention (ERP) are effective therapeutic modalities.
- Trial name
- NCT04594044
- Testing
- tics training including habit reversal training and exposure response prevention
- Volunteers
- 59 people
- Sponsor
- Aarhus University Hospital
Tourette Syndrome
Ecopipam Tablets to Study Tourette's Syndrome in Children and Adolescents
This study evaluates the effect of ecopipam tablets in children and adolescents in the treatment of Tourette's Syndrome (TS). Half of the participants will receive ecopipam tablets, while the other half will receive matching…
- Trial name
- D1AMOND (NCT04007991)
- Testing
- Ecopipam
- Where
- 70 sites in United States, Canada and 3 more
- Volunteers
- 153 people
- Sponsor
- Emalex Biosciences Inc.