Clinical trials: Muscle Activation
Hematopoietic and Lymphatic System Neoplasm, Recurrent Ependymoma
Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial
This phase II pediatric MATCH treatment trial studies how well selpercatinib works in treating patients with solid tumors that may have spread from where they first started to nearby tissue, lymph nodes, or distant parts of the…
- Conditions
- Hematopoietic and Lymphatic System Neoplasm, Recurrent Ependymoma, Recurrent Ewing Sarcoma, Recurrent Hepatoblastoma
- Trial name
- NCT04320888
- Testing
- Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography
- Where
- 174 sites in United States, Australia and 1 more
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute (NCI)
Adolescent Idiopathic Scoliosis
Immediate Effects of Self-Corrective Training in Adolescent Idiopathic Scoliosis: A Nested Study
This nested study was conducted within a broader adolescent idiopathic scoliosis research protocol approved under IRB UW24-747. It evaluated immediate within-session changes in bilateral muscle-activation asymmetry and posterior…
- Trial name
- NCT07194564
- Testing
- Fixed-Sequence Exercise and Self-Corrective Posture Training
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The University of Hong Kong
Life Threatening Diseases
Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases
Exploratory study to examine the effect(s) of Imatinib mesylate treatment on life threatening rare diseases with known associations to one or more Imatinib mesylate -sensitive tyrosine kinases, and to identify the contribution of…
- Trial name
- NCT00154388
- Testing
- Imatinib mesylate
- Volunteers
- 185 people
- Sponsor
- Novartis Pharmaceuticals
Cerebral Palsy (CP), Typically Developing Children
The Effect of Perturbation Training on Reactive Balance in Children With Cerebral Palsy
The aim of this project was to evaluate whether perturbation training influences reflex modulation in children with spastic CP and whether changed reflex modulation leads to improved reactive balance and walking.
- Trial name
- NCT07818928
- Testing
- Balance training on a moving platform
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Idiopathic Scoliosis
The Effect of Back Muscles Activation on Idiopathic Scoliosis Using Surface Electromyography
The purpose of this study is to evaluate the effect of back muscle activations on idiopathic scoliosis
- Trial name
- NCT05333796
- Testing
- gait with leg length discrepancy
- Where
- South Korea
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hyperkyphosis, Adolescent, Muscle Activation
Schroth and Scapular Muscle Activation in Hyperkyphosis
This randomized controlled trial aims to investigate the effects of Schroth exercises on scapular muscle activation in children with thoracic hyperkyphosis.
- Conditions
- Hyperkyphosis, Adolescent, Muscle Activation, Scapula; Deformity, Acquired, Exercise Therapy
- Trial name
- NCT06907914
- Testing
- Schroth
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Obstructive Pulmonary Disease
Comparison of Repetitive Magnetic Stimulation and Exercise on Quadriceps Function in COPD
Background Chronic Obstructive Pulmonary Disease (COPD) patients develop leg weakness and a reduced walking capacity, due to reduced leg muscle oxygen-utilising capacity (OUC).
- Trial name
- NCT00737698
- Testing
- Exercise, Repetitive magnetic stimulation
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cerebral Palsy (CP), Typically Developing Children
Interaction Between Spasticity and the Initial Response After Balance Perturbations in Children With Spastic Cerebral Palsy
The aim of this study was to investigate the link between spasticity and the initial response after standing balance perturbations in children with spastic cerebral palsy.
- Trial name
- NCT07616193
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Adolescent Idiopathic Scoliosis, Diaphragmatic Manual Techniques
Three-Dimensional Scoliosis Exercises and Diaphragmatic Manual Techniques in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine that emerges during growth and is characterized by lateral curvature, vertebral rotation, and trunk asymmetry.
- Conditions
- Adolescent Idiopathic Scoliosis, Diaphragmatic Manual Techniques, Schroth Exercises
- Trial name
- NCT07683533
- Testing
- Diaphragmatic manual techniques, Schroth exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Akdeniz University
Ankle Sprain
Effects of Ankle Support on Muscle Activation and Function
The purpose of this study is to examine the effects of ankle taping on improving muscle function and ankle motion in individuals who frequently twist (sprain) their ankle.
- Trial name
- NCT01423513
- Testing
- Fibular Taping
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Creighton University
Normal Pediatric Swallowing Physiology, Swallowing Muscle Activation Patterns in Children
Surface Electromyographic Analysis of Normal Swallowing in Children: An Exploratory Study
This exploratory clinical trial aims to investigate the mechanism of sequential muscle contractions during normal swallowing processes, including spoon, straw, and cup feeding, in children aged 2 to under 10 years without…
- Conditions
- Normal Pediatric Swallowing Physiology, Swallowing Muscle Activation Patterns in Children, Swallowing Function
- Trial name
- NCT07455279
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Advanced Malignant Solid Neoplasm, Recurrent Ependymal Tumor
Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
This phase II Pediatric MATCH trial studies how well ulixertinib works in treating patients with solid tumors that have spread to other places in the body (advanced), non-Hodgkin lymphoma, or histiocytic disorders that have a…
- Conditions
- Advanced Malignant Solid Neoplasm, Recurrent Ependymal Tumor, Recurrent Ewing Sarcoma, Recurrent Glioma
- Trial name
- NCT03698994
- Testing
- Pharmacokinetic Study, Ulixertinib
- Where
- 107 sites in United States, Puerto Rico
- Volunteers
- 20 people
- Sponsor
- National Cancer Institute (NCI)
Rheumatoid Arthritis, Spondyloarthritis
Pregnancy and Medically Assisted Conception in Rare Diseases
Rare diseases frequently affect women of childbearing age. Pregnancy in these women has become less rare, but remains associated with high levels of complications.
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Psoriatic Arthritis, Systemic Lupus Erythematosus
- Trial name
- EGR2 (NCT02450396)
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healty Volunteers
The Effect of Two Different Exercise Programs in Young Sailors
This study aims to investigate the effects of an 8-week structured land-based exercise program on hiking endurance, core endurance, muscle activation, balance, and motor competence in young sailors.
- Trial name
- NCT07097116
- Testing
- Hiking Bench Exercise Program, Structured Land-Based Exercise Program
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Istinye University
Healthy Volunteers
Angle-Specific Upper and Lower Body Muscle Activation in Suspension Training
The study aims to compare differences in muscle activation during push-ups performed at five body angles using different suspension methods. The investigators will recruit 20 healthy men with resistance-training experience.
- Trial name
- NCT07127211
- Testing
- Suspension and Stable Push-Up Training at Multiple Angles
- Where
- Taiwan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- TSUNG-LIN CHIANG
Adolescent Idiopathic Scoliosis (AIS)
Wireless EMG-Based Monitoring of Paraspinal Muscle Activation in Adolescent Idiopathic Scoliosis
This study aims to develop and evaluate a wireless, non-invasive, embedded electromyography (EMG) system for monitoring paraspinal muscle activation asymmetries in adolescents with idiopathic scoliosis.
- Trial name
- AIS-EMG (NCT07738588)
- Testing
- Wireless Embedded Surface EMG (sEMG) Measurement System
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ertugrul Deniz Kose
Uterine Fibroid
The Role of Fibroblast Activation in Uterine Fibroid
Uterine fibroids (UFs), also called uterine leiomyomas or myomas, are steroid hormone-responsive, benign tumors of the smooth muscle compartment (myometrium) of the uterus.
- Trial name
- NCT03444987
- Testing
- Measurement of protein expression in tissues.
- Where
- Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pelvic Floor Muscle Activation, Idiopathic Scoliosis
Assessment of Pelvic Floor Muscle Activation in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis is a three-dimensional deformity of the spine with a curvature of at least 10° on radiography, accompanied by rotation, seen in children aged 10-18 years, the cause of which is unknown.
- Trial name
- NCT07074873
- Testing
- Descriptive information form, Health-Related Quality of Life Assessment, Trunk rotation angle
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Kinesio Taping
Influence of Kinesio Taping on Muscle Activation, Muscle Strength and Performance of Young Football Athletes Jump
The objective of the project is to investigate the influence of application of Kinesio Taping in young athletes in football, muscle strength and muscle activation in the performance of the Single Leg Hop Test tests and Triple Hop…
- Trial name
- NCT02057120
- Testing
- Kinesio Taping
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Nove de Julho
Unilateral Cerebral Palsy
Sensitivity of an Upper Limb Motion Analysis Protocol to Changes in Kinematics and Muscle Activity After Constraint Induced Therapy in Children With Hemiplegia
In France, Cerebral Palsy (CP) affects 1 in 450 births. It results from lesions of the brain, before, during, or shortly after birth. These non-progressive lesions cause muscle impairments, responsible for activity limitations.
- Trial name
- MouvsupTCIHemi (NCT03099993)
- Testing
- Measurement of maximal forces of elbow pronosupination and flexion-extension
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital