Clinical trials: Muscle Damage
Cerebral Palsy
Strength Training Combined With Blood Flow Restriction and Cerebral Palsy
load resistance exercises are performed while partially restricting venous blood flow to the exercising limb using a pneumatic cuff.
- Trial name
- NCT07748052
- Testing
- strength training combined with blood flow restriction and designed physical therapy program, a specially designed physical therapy program
- Volunteers
- 26 people
- Sponsor
- Cairo University
Cerebral Palsy
Ankle-foot Orthoses for Night Splinting in Children With CP: Impact on Passive Stiffness in Plantarflexors Muscles
Children with cerebral palsy present early in the childhood altered muscular properties, characterized by short muscle belly length and increased stiffness which contribute to contracture and limiting joint range of motion.
- Trial name
- NIGHTSTRETCH (NCT03686644)
- Testing
- Wearing of night splint ankle foot orthoses (phase A), No wearing of night splint ankle foot orthoses (phase B)
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cerebral Palsy, Spasticity
Power Wheelchair Joystick Use in Spastic Cerebral Palsy
There are over 750,000 individuals in the U.S. with Cerebral Palsy (CP). Up to 46% of adults with CP report limited mobility in their communities.
- Trial name
- NCT00337688
- Testing
- isometric joystick
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cerebral Palsy, Spastic
Effect of Functional Power Training on Calf Muscle Length and Strength in Children With Spastic Paresis
Spastic paresis (SP) is a common motor condition in children and is often caused by cerebral palsy. Skeletal muscles develop differently in children with SP due to brain damage in early development; muscle strength and muscle…
- Trial name
- MegaMuscle (NCT05649930)
- Testing
- Functional power training
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- Amsterdam UMC, location VUmc
Cerebral Palsy Spastic Diplegia
Comparative Effects of Play-Based Therapy and NDT in Diplegic CP
To compare the efficacy of play-based therapy versus NDT in improving fine motor skills in children with Spastic Diplegic Cerebral Palsy.
- Trial name
- NCT07534228
- Testing
- Group B Play-Based Therapy, Group A NDT
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Muscle Weakness, Problems Moving Their Arms and Legs
Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults
People with cerebral palsy (CP), muscular dystrophy (MD), spina bifida, or spinal cord injury often have muscle weakness, and problems moving their arms and legs.
- Trial name
- NCT06998134
- Testing
- Extension assist knee ankle foot orthosis (EA-KAFO)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cerebral Palsy, Spasticity, Muscle
Can Transcutaneous Electrical Stimulation Garment Improve Gait in Children With Cerebral Palsy?
Living with cerebral palsy is challenging for the child as well as the family charged with their care and support needs. Many families seek effective and sustainable interventions to improve gait of their children with cerebral…
- Trial name
- NCT04715334
- Testing
- Mollii suit
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- KK Women's and Children's Hospital
Cerebral Palsy
Effect of Radial Shockwave on Calf Muscle Spasticity in Patients With Cerebral Palsy
the aim of this study to assess different outcome measures after applying standard physical therapy plus radial shockwave and compare the results with another group who received standard treatment only.
- Trial name
- NCT05883020
- Testing
- Experimental Interventions, Standard physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- University of Hail
Cerebral Palsy
Telehealth-Supervised Resistance Training for Children With Cerebral Palsy
The goal of this clinical trial is to evaluate the feasibility and potential benefits of telehealth-supervised resistance training in ambulatory children aged 6 to 15 years with cerebral palsy (CP) classified as Gross Motor…
- Trial name
- NCT07061275
- Testing
- Telehealth-Supervised Resistance Training
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Hunan Normal University
Cerebral Palsy
Role of Kinesiotape Over Dorsi Flexors Muscles on Balance in Children With Spastic Diplegia
To detect the effect of kinesio -tape on balance in children with spastic diplegia.
- Trial name
- NCT04243928
- Testing
- kinesio taping
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Spastic Diplegia, Motor Imagery
Effect of Multisensory Motor Imagery Training on Muscle Performance and Coordination in Children With Spastic Diplegia
PURPOSE: The current study aims to: Determine the effect of multisensory motor imagery training on muscle performance including (peak torque, work, power) of trunk and knee flexors and extensors in children with spastic diplegia.
- Trial name
- NCT06676332
- Testing
- motor imagery training, traditional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cerebral Palsy (CP), Spasticity
Predictors of Motor İmagery Performance in Cerebral Palsy
There are very few studies in the literature examining the effect of age on motor imagery ability in children with cerebral palsy. To our knowledge, no studies have investigated the impact of other related factors.
- Conditions
- Cerebral Palsy (CP), Spasticity, Motor Learning
- Trial name
- NCT07002567
- Testing
- Implicit motor imagery, Explicit motor imagery
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy
Robotic-assisted Therapy to Improve Manual Dexterity in Children With Cerebral Palsy
This is an intervention study including a baseline data collection, 6 weeks of robot-assisted training targeting hand dexterity, and a post-intervention data collection.
- Trial name
- NCT02923167
- Testing
- Robotic-assisted training of the hand
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Spaulding Rehabilitation Hospital
Peripheral Arterial Disease
Mechanisms That Produce the Leg Dysfunction of Claudication & Treatment Strategies
Intermittent claudication afflicts 5% of the US population older than 55 years of age and develops along with hardening of the arteries of the legs.
- Trial name
- NCT01970332
- Testing
- Revascularization Surgery, Supervised exercise therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Nebraska
Cerebral Palsy, Movement Disorders in Children
Reliability of Range of Movement Measurements in Cerebral Palsy
The aim is to investigate the inter-rater reliability of passive range of motion (pROM) measurement with goniometer of knee extension and ankle dorsiflexion for children with unilateral spastic cerebral palsy (USCP) and secondary…
- Trial name
- NCT06295107
- Testing
- Ankle Passive Range of Movement (pROM), Knee Passive Range of Movement (pROM)
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Region Skane
Cerebral Palsy, Whole Body Vibration
Effects of WBV in Children With Hemiparetic CP
The aim of this study was to investigate short and long-term effects of Whole Body Vibration therapy on spasticity and motor performance in children with hemiparetic cerebral palsy in addition to conventional physiotherapy.
- Conditions
- Cerebral Palsy, Whole Body Vibration, Spastic Hemiplegia, Motor Performance
- Trial name
- NCT04528966
- Testing
- Whole-Body Vibration, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Pamukkale University
Cerebral Palsy, Spastic
Progressive Supervised Home-based Strength Training in Children With Spastic Cerebral Palsy
A randomized controlled trail will be carried out to investigate the effect of a 12-week supervised home-based progressive strength intervention in children with spastic cerebral palsy aged 5-11 years.
- Trial name
- NCT03863197
- Testing
- Progressive strength training
- Where
- 2 sites in Belgium
- Volunteers
- 49 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy, Genetic Disease
Genetic Etiology in Patients With Cerebral Palsy
Cerebral palsy (CP) is a permanent disorder of movement or posture due to non-progressive impairments of the developing brain. Current estimates indicate that as many as 30% of CP cases may be genetic in nature.
- Conditions
- Cerebral Palsy, Genetic Disease, Developmental Delay, Metabolism, Inborn Errors
- Trial name
- GenCP (NCT05123768)
- Testing
- NGS
- Where
- Slovenia
- Volunteers
- 150 people
- Sponsor
- University Medical Centre Ljubljana
Cerebral Palsy, Spastic
Whole-body Vibration in Spastic Hemiplegic Cerebral Palsy
To target spasticity, balance and mobility whole body vibration exercises along with selected physical therapy is given to experimental group.
- Trial name
- NCT04087330
- Testing
- Group 1 Experimental group, Group 2 Control group
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Cerebral Palsy (CP)
Targeted Muscle Activation During Strength Training for Children With CP
Cerebral palsy (CP) is the most common cause of physical disability in children and is associated with muscle weakness, spasticity, and impaired motor control.
- Trial name
- TACT-CP (NCT07800221)
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven