Clinical trials: Muscle Damage
Spastic Cerebral Palsy
A Physical Therapy Program Targeting Lower Extremity Selective Motor Control in Children With Spastic Cerebral Palsy
The goal of this intervention study is to learn whether a physical therapy exercise camp called will improve leg movement (motor control) and functional ability in children with spastic CP who are between 5 and 18 years.
- Trial name
- NCT07310550
- Testing
- Selective movement of individual lower limb joints, Knee joint strengthening at high velocities, Ankle controlled gaming
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, Los Angeles
Spasticity, Muscle, Cerebral Palsy
Effect of Number of Pulses of Radial Extracorporeal Shock Wave Therapy on Hamstring Spasticity in Children With Cerebral Palsy
Cerebral palsy (CP) is a group of permanent disorders affecting movement and postural development that are caused by non-progressive disruptions of the brain, usually occurring during fetal period or infancy.
- Conditions
- Spasticity, Muscle, Cerebral Palsy, Child; Spastic
- Trial name
- NCT04546035
- Testing
- radial Extracorporeal Shockwave Therapy
- Where
- Indonesia
- Volunteers
- 13 people
- Sponsor
- Rizky Kusuma Wardhani
Cerebral Palsy, Weakness
Use of Surface Electromyography Biofeedback to Improve Reaching in Children With Cerebral Palsy
A newly-developed device for biofeedback of surface EMG will be used to either increase or decrease activity in the muscles of children with poor reaching due to cerebral palsy.
- Conditions
- Cerebral Palsy, Weakness, Hypertonia
- Trial name
- NCT00473161
- Testing
- surface EMG biofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Cerebral Palsy, Multiple Sclerosis
The EXOPULSE Study - a Database for Routine Follow-up of Clinical Outcomes
The objective is to explore the potential short and long-term impact of the EXOPULSE Mollii Suit and EXOPULSE Suit on subjects with CP, MS, stroke, fibromyalgia or other neurologic disorders which may cause such types of…
- Conditions
- Cerebral Palsy, Multiple Sclerosis, Stroke, Neurologic Disorder
- Trial name
- EXOREG (NCT05901259)
- Testing
- EXOPULSE Mollii Suit and EXOPULSE Suit
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Cerebral Palsy, Spastic
Core Strength for Head Control and Quality of Life in Cerebral Palsy
The goal of this observational study is to examine the effect of an 8-week therapist-assisted core muscle strengthening program on head control, trunk stability, functional core strength, quality of life, and automatic righting…
- Trial name
- NCT07613515
- Testing
- Core Strength Training
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Cairo University
Cerebral Palsy, Spastic
Role Of Physical Therapy In Relieving Constipation In Children With Spastic Cerebral Palsy
This study was conducted to determine the effectiveness of Physical Therapy management in relieving constipation among Spastic Cerebral Palsy children.
- Trial name
- NCT03379038
- Testing
- Progressive Physical Therapy, Maintenance Physical Therapy
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- Isra University
Cerebral Palsy (CP), Typically Developing Children
The Effect of Perturbation Training on Reactive Balance in Children With Cerebral Palsy
The aim of this project was to evaluate whether perturbation training influences reflex modulation in children with spastic CP and whether changed reflex modulation leads to improved reactive balance and walking.
- Trial name
- NCT07818928
- Testing
- Balance training on a moving platform
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy (CP)
Pediatric Endurance and Limb Strengthening Program With and Without Electrical Muscle Stimulation Among Children With Cerebral Palsy
This randomized clinical research will assess the impact of a Pediatric Endurance and Limb Strengthening (PEDAL) program, both with and without Electrical Muscle Stimulation (EMS), on balance, gait, and mobility in children…
- Trial name
- NCT07173647
- Testing
- PEDAL Program with Electrical Muscle Stimulation, PEDAL Program without Electrical Muscle Stimulation
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- University of Lahore
Premature Birth, Cerebral Palsy
Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants
This project focuses on motor development, muscle growth and muscle activity. Using advanced, instrumented tests such as , the link between muscles and the movement characteristics will be studied.
- Conditions
- Premature Birth, Cerebral Palsy, Neurodevelopmental Disorders, Brain Injuries
- Trial name
- BAMBI (NCT06111898)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Cerebral Palsy (CP), Diaplegia
Effect of Treatment on Cerebral Palsy Patient With Crouch Gait Associated With Anterior Pelvic Tilt and Soleus Muscle Weakness"Marouf Syndrome", and Muscle Assesment by Using EMG
Children with cerebral palsy (CP) often develop gait abnormalities, with crouch gait being a common and challenging issue that affects their posture and daily function.
- Conditions
- Cerebral Palsy (CP), Diaplegia, Muscle Weakness | Patient, Anterior Pelvic Tilt
- Trial name
- NCT07147933
- Testing
- phusical therapy program, physical therapy program
- Where
- Jordan
- Volunteers
- 40 people
- Sponsor
- Philadelphia University, Jordan
Cerebral Palsy, Spastic
Effect of Vibration on Muscle Properties, Physical Activity and Balance in Children with Cerebral Palsy
The aim of the 6-month randomized controlled trial, with 6-month no treatment follow-up, is to examine the effects of low-magnitude vibration on muscle, physical activity, and balance in children with spastic cerebral palsy.
- Trial name
- NCT03484078
- Testing
- Vibration Platform
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Georgia
C10.228.140.140.254
The Socioeconomic Status and Child Characteristics on the Physical Therapy Outcome in Children With Spastic Cerebral Palsy
The main outcome of physical therapy interventions is the progress of gross motor functions which result from the interactions between many factors not limited to physical, medical or surgical interventions but also including…
- Trial name
- NCT04160403
- Testing
- physical therapy intervention
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zeinab Hussein
Hemiplegic Cerebral Palsy
Modified Constraint Induced Movement Therapy Versus Virtual Reality Training in Children With Cerebral Palsy
Children with hemiplegic cerebral palsy (CP) are characterized by motor impairments mainly lateralized to one side of the body, with greater upper limb than lower limb involvement; these impairments may further limit the daily…
- Trial name
- NCT06846190
- Testing
- mCIMT, VR
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Spastic Diplegic Cerebral Palsy, Hemiplegic Cerebral Palsy
Strength Training in Children With Spastic Diplegic and Hemiplegic Cerebral Palsy Receiving Botulinum Toxin
To estimate the effectiveness of strength training after administration of botulinum toxin in children with spastic diplegic cerebral palsy and hemiplegic cerebral palsy on muscle volume and gross motor function.
- Trial name
- NCT04177186
- Testing
- Strength training, Strength training with botulinum toxin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Cerebral Palsy
Use of Transcranial Magnetic Stimulation and Constraint Induced Movement Therapy in Pediatric Unilateral Cerebral Palsy
Cerebral Palsy (CP) is the most common cause of childhood physical disability. Early CP diagnosis and intervention are crucial to improving outcomes in these patients.
- Trial name
- NCT04902521
- Testing
- Transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Recurrent Crying Spells
Recurrent Crying Spells in Cerebral Palsy
This is a study of recurrent crying spells in Spastic Cerebral Palsy patients and their treatment.
- Trial name
- RCSCPSQ (NCT01955655)
- Testing
- Baclofen
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Sathbhavana Brain Clinic
Cerebral Palsy, SMA II
Evaluation of the Exoskeleton ATLAS 2030 as Robot-assisted Physical Therapy to Children With Neuromuscular Diseases
This study aims to evaluate the safety, usability and acceptability of a motorized mobility assistance exoskeleton. The protocol explores the use of the motorized device during static and dynamic rehabilitation sessions focused…
- Conditions
- Cerebral Palsy, SMA II, Neuromuscular Diseases
- Trial name
- NCT04837157
- Testing
- Exoskeleton rehabilitation
- Where
- Spain
- Volunteers
- 6 people
- Sponsor
- MarsiBionics
Spastic Cerebral Palsy
Prospective Studies of the Use of Self Hypnosis, Acupuncture and Osteopathic Manipulation on Muscle Tension in Children With Spastic Cerebral Palsy
We propose to identify patients and families for inclusion in pilot studies of the three modalities. Patients and their families will be asked to participate in these studies.
- Trial name
- NCT00011024
- Testing
- Self Hypnosis, Acupuncture, Osteopathic Manipulation
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Cerebral Palsy Spastic Diplegia
Effect of Botulinum Toxin on Selective Motor Control and Pain in Diplegic Cerebral Palsy
The aim of this study is to investigate the effects of Botulinum Neurotoxin-A (BoNT-A) injection applied to spastic muscles on pain sensation and Selective Motor Control (SMC) in cases diagnosed with diplegic spastic Cerebral…
- Trial name
- NCT06583343
- Testing
- OnabotulinumtoxinA, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Rehabilitation, Cerebral Palsy (CP)
Effects of Motor Imagery Training After Muscle Lengthening Surgery in Children With Cerebral Palsy
In children with cerebral palsy (CP), spasticity occurs in the muscles due to upper motor neuron lesions. The muscle groups that are mostly spastic in the lower extremity are; the hip adductor and flexors, hamstrings, and ankle…
- Conditions
- Rehabilitation, Cerebral Palsy (CP), Exercise, Tenotomy
- Trial name
- NCT06838858
- Testing
- Motor Imagery Training, Conventional Post-operative Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Saglik Bilimleri Universitesi