Clinical trials: Muscle Protein Synthesis
Spinal Muscular Atrophy
Motor Function and Activity of Daily Life in Spinal Muscular Atrophy
This study will incorporate patients/ caregivers' perspectives to investigate the performance in daily activities of individuals with SMA and how it relates to their motor function abilities.
- Trial name
- NCT05931211
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Crohn Disease
ProteIn Nutrition in Crohn's Disease
Muscles are essential for good quality of life. The investigators have shown that when children with Crohn's disease eat protein, only very little of it enters the muscles, leading to poor muscle growth and fatigue.
- Trial name
- PINC (NCT05572008)
- Testing
- Protein nutrition in paediatric Crohn's disease
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Phenylketonuria, PKU
Moderate Intensity Exercise and Phenylketonuria
Phenylketonuria (PKU), an inherited genetic disorder, can cause irreversible brain damage, declined executive function, and autistic tendencies unless a phenylalanine (Phe) restricted diet is consistently maintained throughout…
- Trial name
- NCT01904708
- Testing
- Acute Moderate Intensity Exercise
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Oregon Health and Science University
Dietary Supplementation, Exercise
Resistance Exercise-induced Anabolism in Youths and Adults
Resistance exercise training (RET) in children and adolescents has become a popular area of research, with a growing body of evidence supporting its use.
- Trial name
- NCT06256744
- Testing
- exercise
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brock University
Motor Disorder, Reliability and Validity
Turkish Translation , Validity and Reliability of the Hypertonia Assessment Tool in Children With Motor Disorders
Translating batteries with good psychometric properties into Turkish will increase the number of assessment batteries we can use in our language for clinical and academic studies.
- Conditions
- Motor Disorder, Reliability and Validity, Hypertonia
- Trial name
- NCT07267442
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kastamonu University
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Muscle Disuse, Muscle Disuse Atrophy
Muscle Response to Different Amounts of Dietary Protein During Leg Immobilization
Individuals who sustain musculoskeletal injuries (MSKI) can experience a rapid loss of muscle mass due to declines in muscle loading and activation that occur post-injury (i.e., disuse atrophy).
- Trial name
- NCT07069426
- Testing
- 20 grams protein, 40 grams protein
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Duchenne Muscular Dystrophy
Open Label Extension Study of HT-100 in Patients With DMD
This study is designed to provide 6-months continuous dosing with the study medication, called HT-100, on participants who successfully completed the predecessor study (HALO-DMD-01).
- Trial name
- NCT01978366
- Testing
- HT-100
- Where
- 5 sites in United States
- Volunteers
- 17 people
- Sponsor
- Processa Pharmaceuticals
Duchenne Muscular Dystrophy
Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of HT-100 in Duchenne Muscular Dystrophy
The main purpose of this study is to test the safety and tolerability of different, increasing doses of an experimental medication called HT-100 in boys and young men with Duchenne muscular dystrophy (DMD).
- Trial name
- NCT01847573
- Testing
- HT-100
- Where
- 5 sites in United States
- Volunteers
- 17 people
- Sponsor
- Processa Pharmaceuticals