Clinical trials: Muscle Relaxants
Target Drug-related Adverse Events
Standard of Care Versus Urine Testing With Selective PHarmacogenomics for Effective Drug and Dosing REgimens
The purpose of this study is to determine whether the addition of selective pharmacogenomic (PGx) testing as determined by Urine Drug Testing (UDT) adds a clinical benefit as evidenced by a reduction in Target Drug-related…
- Trial name
- SPHERE (NCT02625155)
- Testing
- Urine diagnostic testing as SOC, drug regimen changes per SOC, Urine diagnostic testing with selective PGx testing, drug regimen changes based on PGx test results
- Where
- United States
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- InSource Diagnostics
Postoperative Residual Curarization
Muscle Relaxants and Post-Anesthesia Complications
This Germany-wide, multi-center, epidemiologic study is designed to evaluate the incidence of post-operative/anesthesia effects of muscle relaxants (i.e.
- Trial name
- PORC (NCT00753389)
- Testing
- None (anesthesia)
- Where
- Germany
- Volunteers
- 20,000 people
- Sponsor
- Technical University of Munich
Sugammadex
Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates
The primary aim of the work is to compare the efficacy of Sugammadex and neostigmine in reversing rocuronium-induced muscle relaxation to reach complete recovery of neuromuscular block (TOF ratio≥ 0.9) in preterm neonates.
- Trial name
- NCT04566796
- Testing
- Sugammadex, Neostigmine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Muscle Relaxants
The Effect of no Muscle Relaxant Versus Reduced-dose Rocuronium on Anesthesia in Adenotonsillectomy
This study aimed to compare the effect of no muscle relaxants and reduced-dose rocuronium on the anesthetic induction and emergence with fentanyl in children undergoing adenotonsillectomy.
- Trial name
- NCT02467595
- Testing
- Rocuronium bromide 0.15 mg kg-1, Rocuronium bromide 0.3 mg kg-1, Fentanyl
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Neuromuscular Blockade
Myorelaxation Practice in Paediatric Anesthesia
In retrospective data search the investigators will identified the percentage of patients with muscle relaxants administered during perioperative period.
- Trial name
- PAMPE (NCT03086915)
- Testing
- Neuromuscular Blocking Agent
- Where
- Czechia
- Volunteers
- 1,650 people
- Sponsor
- Brno University Hospital
Muscle Relaxation
Interindividual Variability in Duration of Action of Rocuronium in Pediatric Patients
Muscle relaxants represent an important part of general anesthesia in adult and pediatric patients. Their role is to facilitate intubation and enable some surgical interventions.
- Trial name
- DurAct (NCT05529420)
- Testing
- measurement of the depth of neuromuscular blockade
- Where
- Czechia
- Volunteers
- 107 people
- Sponsor
- Brno University Hospital
Anesthesia, Neuromuscular Blockade
Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants
Although tonsillectomy is one of the most commonly performed surgeries, a review of literature reveals no articles dealing with the study of intraoperative blood loss in tonsillectomy and adenotonsillectomy according to the use…
- Conditions
- Anesthesia, Neuromuscular Blockade, Intraoperative Bleeding, Intraoperative Blood Loss
- Trial name
- NCT06399445
- Testing
- conventional cold tonsillectomy and curettage adenoidectomy, Rocuronium Bromide
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital of Split
Anesthesia Intubation Complication
Fentanyl and Propofol for Tracheal Intubation During Sevoflurane Induction Without Muscle Relaxants in Children
Several methods have been proposed to improve intubating conditions and minimize sevoflurane induction time during sevoflurane induction in children.
- Trial name
- NCT02442128
- Testing
- propofol /Fentanyl, Fentanyl / propofol
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- King Saud University
Inguinal Hernia, Endotracheal Intubation
Pediatric Inguinal Hernia Repair: Are Muscle Relaxants Necessary? Endotracheal Intubation vs Laryngeal Mask Airway
In prospective, safety-control study; children undergoing laparoscopic inguinal hernia repair using PIRS (Percutaneous Internal Ring Suturing) method will be randomly assigned into four groups.
- Conditions
- Inguinal Hernia, Endotracheal Intubation, Laryngeal Mask, Muscle Relaxants
- Trial name
- NCT02696837
- Testing
- ETT, Proseal LMA, Rocuronium
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Maltepe University
Anesthesia Intubation Complication
Muscle Relaxants on Efficacy of LMA Insertion
The use of laryngeal mask airway (LMA) is increasing in pediatric anesthesia because it provides lesser direct mechanical stimulation of the airway due to being placed above the larynx.
- Trial name
- LMA_MR (NCT03487003)
- Testing
- rocuronium, saline
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Daegu Catholic University Medical Center