Clinical trials: Muscle Weakness | Patient
Sugammadex Reversal Time, Muscle Weakness
The Effect of Methylprednisolone on the Reversal Time of Rocuronium by Sugammadex in the Pediatric Patient Group
The aim of this study is to thoroughly investigate the interaction between methylprednisolone and sugammadex in the pediatric patient population.
- Trial name
- NCT06623370
- Testing
- methylprednisolone
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Cerebral Palsy, Perceptual Disorders
Motor and Cognitive Functions in Acquired and Developmental Brain Damaged Patients
Neurological pathologies cause important and permanent disabilities in every day life. These pathologies can follow stoke, affecting two people per one thousand each year or cerebral palsy, affecting two births per one thousand…
- Conditions
- Cerebral Palsy, Perceptual Disorders, Hemiparesis
- Trial name
- NCT02543424
- Testing
- Motor, cognitive and neuropsychological assessment
- Where
- 2 sites in Belgium
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
COPD, Muscle Weakness
Feasibility of Strength Training in Patients Hospitalized Due to COPD
To examine the feasibility of progressive unilateral knee-extension strength training using ankle weight cuffs in patients hospitalized due to acute exacerbation in COPD
- Trial name
- NCT01981200
- Testing
- Resistance training in AECOPD
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Frederikssunds Hospital, Denmark
Neck of Femur Fracture
PENG Versus Femoral Nerve Block in Neck of Femur Fracture
Neck of femur (NOF) fracture is a common presentation to the emergency department, particularly in our older population. NOF fracture is associated with a high social and economic cost with significant effects on patients'…
- Trial name
- NCT05002725
- Testing
- Lidocain
- Where
- Ireland
- Volunteers
- 64 people
- Sponsor
- University College Cork
Cerebral Palsy, Upper Extremity Paresis
Virtual Reality Mediated Upper Extremity rehabilitationPatients With Cerebral Palsy
Cerebral palsy (CP) refers to a group of permanent disorders that occur in the brain of the fetus or infant, which are non-progressive, cause movement and posture disorder along with activity limitation.
- Trial name
- NCT04529343
- Testing
- Virtual reality mediated upper extremity rehabilitation, Classical exercise therapy for upper extremities
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Vocal Cord Dysfunction, Vocal Cord Paralysis
Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure
The goal of this prospective, observational study is to evaluate for the presence of vocal fold motion impairment (VFMI) in the children admitted to the pediatric intensive care unit on noninvasive positive pressure ventilation…
- Conditions
- Vocal Cord Dysfunction, Vocal Cord Paralysis, Vocal Cord Paresis, Recurrent Laryngeal Nerve Palsy
- Trial name
- NCT06406725
- Testing
- Point-of-Care Ultrasound of the Airway
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Spastic Hemiplegic Cerebral Palsy, Upper Extremity Paresis
The Effects of Upper Extremity Robotic Rehabilitation in Children With Spastic Hemiparetic Cerebral Palsy
Aims: To investigate the effects of upper extremity robotic rehabilitation on upper extremity skills and functional independence level in patients with hemiparetic Cerebral Palsy (hCP).
- Conditions
- Spastic Hemiplegic Cerebral Palsy, Upper Extremity Paresis, Robotic Rehabilitation
- Trial name
- NCT06352762
- Testing
- Conventional physiotherapy, Robotic Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Izmir Bakircay University
Thymidine Kinase 2 Deficiency
An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency
This is a Phase 2 prospective open-label treatment study of the safety and efficacy of doxecitine and doxribtimine in study participants with thymidine kinase 2 (TK2) deficiency who participated in the retrospective study…
- Trial name
- Continuation (NCT03845712)
- Testing
- doxecitine and doxribtimine
- Where
- 8 sites in United States, Israel and 1 more
- Volunteers
- 47 people
- Sponsor
- UCB BIOSCIENCES, Inc.
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
Muscle Weakness
Maximal Strength Training in Patients Undergoing Total Hip Arthroplasty
Conventional rehabilitation after total hip arthroplasty (THA) does not seem to restore muscular strength or walking speed. Three-5 years after surgery patients are still not fully rehabilitated.
- Trial name
- NCT02498093
- Testing
- Maximal strength training, conventional rehabilitation
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Cerebral Palsy, Movement Disorder
Rehabilitation Gaming System for Cerebral Palsy
In this study the investigators evaluate the effectivity of Virtual Reality-based rehabilitation protocols for preventing motor deterioration in patients with cerebral palsy.
- Trial name
- NCT02938754
- Testing
- VR-based motor training, Conventional Therapy
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Universitat Pompeu Fabra
Muscle Weakness, Critical Illness
Critical Illness Neuromuscular Abnormalities in Neurocritical Care Patients
The aim of this research is to investigate critical illness neuromuscular abnormalities in neurocritical care patients.
- Trial name
- NCT00893633
- Where
- Russia
- Volunteers
- 135 people
- Sponsor
- Clinical Institute of the Brain, Russia
Thymidine Kinase 2 (TK2)
A RETROspective Study of Patients With TK2d
This is a medical chart review study to collect information for patients who have been taking pyrimidine nucleosides for treatment of TK2 deficiency.
- Trial name
- RETRO (NCT03701568)
- Testing
- dC/dT
- Where
- 8 sites in United States, Israel and 1 more
- Volunteers
- 38 people
- Sponsor
- Zogenix MDS, Inc.
Gait Impairment, Cerebral Palsy (CP)
Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program…
- Conditions
- Gait Impairment, Cerebral Palsy (CP), Neuromuscular Diseases (NMD), Spinal Cord Injuries (SCI)
- Trial name
- NCT07745712
- Testing
- ABLE Kids
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- ABLE Human Motion S.L.
Critical Illness, Intensive Care
Early Exercise Training in Critically Ill Patients
This randomized controlled trial was designed to investigate whether a daily training session using a bedside cycle ergometer, started early in stable critically ill patients with an expected prolonged ICU stay, could induce a…
- Conditions
- Critical Illness, Intensive Care, Muscle Weakness, Deconditioning
- Trial name
- NCT00695383
- Testing
- Bedside cycle exercise therapy, Standard physiotherapy program
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Muscle Weakness, Late Effect of Burn
Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients
This study will measure efficacy of early in-patient exercise as an adjunct to current Standard of Care (SOC) for 96 patients in a multi-centre trial.
- Conditions
- Muscle Weakness, Late Effect of Burn, Muscle; Fatigue, Heart, Burn Rehabilitation
- Trial name
- MP-10 (NCT02739464)
- Testing
- Exercise + SOC PT/OT, SOC PT/OT
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Respiratory Complication, Morbid Obesity
Does Residual Muscular Weakness Lead to an Increase in Respiratory Complications in Bariatric Patients?
The purpose of this study is to determine if residual weakness after weight loss surgery leads to an increased risk of respiratory complications in the postoperative period.
- Trial name
- NCT02037516
- Testing
- Accelomyography, Neostigmine, Qualitative Monitor
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Coastal Anesthesiology Consultants
Paraparesis, Tetraparesis
Prospective Cohort Follow-up of French Patients With Profound and Multiple Disabilities: Healthcare Pathways and Quality of Life Among Patients and Their Families
The studies conducted so far concerning the medical and paramedical cares provided to patients with profound and multiple disabilities (PMD) often show important limitations: samples are too small or very heterogeneous, generally…
- Conditions
- Paraparesis, Tetraparesis, Hemiparesis, Ataxia
- Trial name
- Eval-PLH (NCT02400528)
- Testing
- quality of life questionnaires
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Neuromuscular; Disorder, Hereditary, Duchenne/Becker Muscular Dystrophy
Molecular Analysis of Patients With Neuromuscular Disease
The purpose of this study is to identify new genes responsible for neuromuscular disorders and study muscle tissue of patient with known neuromuscular disease, as well as their family members.
- Conditions
- Neuromuscular; Disorder, Hereditary, Duchenne/Becker Muscular Dystrophy, Limb-girdle Muscular Dystrophy
- Trial name
- NCT00390104
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Boston Children's Hospital
Pareses, Lower Extremity
C-Brace Prospective Registry
To gather prospective safety and effectiveness data for the C-Brace System following the standard of care.
- Trial name
- NCT04640584
- Testing
- C-Brace
- Where
- 76 sites in United States, Australia and 2 more
- Volunteers
- 250 people
- Sponsor
- Otto Bock Healthcare Products GmbH