Clinical trials: Myopia; Refractive Error
Myopia
Efficacy and Safety of Defocusing Frame Glasses With Artificial Intelligence in Controlling Myopia Progression
Background: Myopia refers to the pathological state in which the external parallel light enters the eye and focuses in front of the retina, resulting in the inability to clearly image on the retina.
- Trial name
- NCT05532774
- Testing
- AI defocusing frame glasses
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Astigmatism
Evaluation of Orthokeratology Lenses With a 5MM Optic Zone Diameter
To evaluate the clinical performance and user-reported experience of Paragon CRT contact lenses with a 5mm Optic Zone Diameter (OZD)
- Trial name
- NCT07751172
- Testing
- Lens A (paflufocon D)
- Where
- 3 sites in United States, Spain
- Volunteers
- 70 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Zhaoqing Myopia Study
Myopia is a common cause of vision loss, being particularly prevalent in children in East and Southeast Asia. The investigators will assess prevalence and incidence of myopia, identify digital biomarkers associated with myopia…
- Trial name
- NCT04219228
- Testing
- Ophthalmic examinations, Wearable devices
- Where
- 2 sites in China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Obesity, Myopia
Beijing (Peking)---Myopia and Obesity Comorbidity Intervention (BMOCI)
Based on the RE-AIM framework, this project intends to integrate the prevention and control measures of myopia and obesity, and establish a set of key suitable technical packages and guarantee systems for the…
- Trial name
- NCT05275959
- Testing
- A cluster randomized trial of a comprehensive intervention nesting family and clinic into school centered implementation to reduce myopia and obesity among children and adolescents in Beijing, China
- Where
- 3 sites in China
- Volunteers
- 3,963 people, healthy volunteers welcome
- Sponsor
- Peking University
Myopia
Adaptation To and Satisfaction With Contact Lens Wear In Myopic Young Adults
The purpose of this study was to assess whether young adults could adapt to and achieve satisfaction with a daily disposable contact lens.
- Trial name
- NCT04857723
- Testing
- daily disposable contact lens
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Efficacy and Safety of MiSight ® Contact Lenses in Reducing the Progression of Childhood Myopia.
The purpose of the study is to quantify the effectiveness of CooperVision MiSight® (omafilcon A) soft (hydrophilic) contact lens in slowing the rate of progression of juvenile-onset myopia.
- Trial name
- NCT01917110
- Testing
- omafilcon A, Spectacle
- Where
- Spain
- Volunteers
- 79 people
- Sponsor
- CooperVision, Inc.
Myopia
Eye Exercise, Transcutaneous Electrical Nerve Stimulation on Prevention of Myopia Progression
In Taiwan, the increasing prevalence of myopia shows a decline with age. Myopia has become a serious ocular problem in children because high myopia may lead to retinal damage, cataract and glaucoma.
- Trial name
- NCT04017234
- Testing
- frequency following response, eye exercise, and transcutaneous
- Where
- Taiwan
- Volunteers
- 27 people
- Sponsor
- China Medical University Hospital
Myopia, Visual Rehabilitation
Exploring Perceptual Learning in Blurred Gabor Discrimination for Low-Myopic Children
This exploratory study investigates whether perceptual learning using blurred Gabor stimuli can improve uncorrected distance visual acuity in children aged 6-10 years with low myopia.
- Conditions
- Myopia, Visual Rehabilitation, Perceptual Learning
- Trial name
- NCT07107646
- Testing
- vision training system, VTS
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Myopia
650nm Low-level Red-light for Myopia Control and Prevention in Children
A multicenter randomized controlled trial, evaluating the efficacy and safety of 650nm low-level red-light irradiation for myopia control and prevention in children.
- Trial name
- NCT05786586
- Testing
- 650 nm low-level red-light
- Where
- China
- Volunteers
- 572 people
- Sponsor
- Beijing Tongren Hospital
Myopia, Randomized Controlled Trial (RCT)
The Rebound Effect on Repeated Low-Level Red Light Therapy for Myopia
Myopia is a global public health issue, projected to affect 49.8% of the world population by 2050, increasing risks of cataracts, glaucoma, macular degeneration, and retinal detachment.
- Trial name
- NCT07748546
- Testing
- Repeated low-level red light (RLRL) therapy
- Volunteers
- 159 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Myopia, Strabismus
Evaluation of a County-Based Eye Health Service Model in Rural Chinese Children
This project proposes to conduct a prospective, multicenter registry study in rural China to evaluate, under real-world conditions, the implementation effectiveness of an integrated child eye health service model centered at the…
- Conditions
- Myopia, Strabismus, Eye Health
- Trial name
- NCT07547748
- Testing
- School-based Eye Health Screening
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Clinical Comparison of Two Daily Disposable Contact Lenses in a Population of Daily Disposable Contact Lens Wearers
The purpose of this study is to evaluate the performance of two commercially marketed daily disposable contact lenses in a population of daily disposable contact lens wearers.
- Trial name
- NCT01233076
- Testing
- Nelfilcon A contact lens, Narafilcon B contact lens
- Volunteers
- 60 people
- Sponsor
- CIBA VISION
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC
Myopia
Effects of 650nm Low Energy Light on Human Retina and Choroid Microcirculation
This project is a single-center, prospective, self-controlled clinical study. It intends to select patients with simple medium and low degree myopia as subjects, and apply 650nm low-energy red light irradiation to the retina to…
- Trial name
- NCT04604405
- Testing
- photobiomodulation
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Central South University
Astigmatism, Myopia
Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism
The purpose of this trial is to compare the performance of two contact lenses for contact lens wearers with astigmatism.
- Trial name
- NCT01207466
- Testing
- Nelfilcon A investigational contact lens, Nelfilcon A commercial contact lens
- Volunteers
- 95 people
- Sponsor
- CIBA VISION
Myopia
Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Daily Disposable Lens Wearers
The purpose of this study is to evaluate the extent to which symptoms improve in symptomatic contact lens wearers when fit with one of two different daily disposable contact lenses.
- Trial name
- NCT01035905
- Testing
- Nelfilcon A contact lens, Narafilcon A contact lens
- Volunteers
- 63 people
- Sponsor
- CIBA VISION
Myopia
Visual Performance of Highly Aspherical Lenslet Spectacles in Children (Ancillary to WS10246)
To evaluate the visual performance of (high and low contrast distance visual acuity, reading speed, near visual acuity, and near contrast sensitivity) of HAL spectacle lenses (habitual correction) in comparison with single vision…
- Trial name
- FIN-3102 (NCT07668102)
- Testing
- HAL spectacle lens, Single Vision spectacle lens
- Where
- 7 sites in United States
- Volunteers
- 88 people
- Sponsor
- Essilor International
Myopia
Defocus (DIMS) Spectacles Versus Ortho-K Lenses (OKL) for Slowing Myopia Progression in Children Aged 6-12 Years.
The goal of this non-inferiority randomized clinical trial is to compare the myopia control efficacy of Ortho-K lenses (OKL) and Defocus (DIMS) spectacles in myopic children aged 6-12 years.
- Trial name
- NISDO (NCT05134935)
- Testing
- Defocus Incorporated Multiple Segment (DIMS) Spectacles, Orthokerathology lenses (OKL)
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Vejle Hospital
Myopia
Assessing the Impact of Streetscape Exposure on Children's Perception
The primary objective is to determine how streetscape exposure influences children's visual perception and psychological perception.
- Trial name
- NCT07761949
- Testing
- Virtual simulation of street visual environment exposure
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
The Effects of Low-dose Atropine and Orthokeratology in Pediatric Myopia Control
Both orthokeratology and atropine eye drops are effective methods for myopia control, but few studies have compared them all together simultaneously.
- Trial name
- AVO (NCT05478356)
- Testing
- low-dose atropine eye drops, orthokeratology
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Evidence Based Cataract Study Group