Clinical trials: Nasal Obstruction
Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum
Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Postoperative agitation is an important complication of general anesthesia, moreover, it has been found with high incidence in ear, nose, throat (ENT) surgeries.
- Conditions
- Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum, Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
- Trial name
- NCT03427502
- Testing
- Bupivacaine-epinephrine, normal saline
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Lumbini Medical College
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Nasal Congestion and Inflammations
Safety and Effectiveness of Sonu for Pediatric Nasal Congestion
To demonstrate the safety and effectiveness of Sonu for the treatment of pediatric patients with moderate to severe nasal congestion.
- Trial name
- NCT06773013
- Testing
- Acoustic Resonance (Sound) Therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Third Wave Therapeutics
Treatment of the Signs and Symptoms of Seasonal Allergic Rhinitis
A Comparison of Mometasone Nasal Spray, Nasonex Nasal Spray, Nasonex Nasal Spray Suspension, & Placebo for Treatment of Seasonal Allergies for Safety, Efficacy, & Superiority in 1520 Male & Female Volunteers
The study will compare the safety and efficacy of a generic mometasone nasal spray to the reference listed drugs in the treatment of seasonal allergic rhinitis.
- Trial name
- NCT02109185
- Testing
- Mometasone Furoate Monohydrate Nasal Spray, 50 μg/act., Nasonex® Nasal Spray, 50 μg/actuation, Nasonex® Nasal Spray Suspnsn, 50 μg/actuation
- Volunteers
- 1,307 people
- Sponsor
- Mylan Pharmaceuticals Inc
Magnetic Resonance Angiography
Fatal Cerebral Infarction After Nasal Augmentation With Hyaluronic Acid
this study discussed the pathogenesis, treatment, and prognosis of severe cerebral infarction and ophthalmic artery occlusion for Aisan induced by hyalruonic acid filler injection.
- Trial name
- NCT04189068
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Xijing Hospital
Atopic Rhinitis, Atopic Asthma
Vibroacoustic Therapy With Oscillating Positive Expiratory Pressure in the Treatment of Nasal Congestion
This is a prospective study. It enrolls subjects with allergic rhinitis, with or without asthma, who have nasal congestion as the main symptom and meet the inclusion criteria, aiming to evaluate the efficacy and safety of…
- Trial name
- VAT (NCT07114107)
- Testing
- VPAT (Vibratory Positive Pressure Therapeutic Apparatus）, basic medications (antihistamines, mometasone furoate nasal spray, ICS-LABA, OPEP（Oscillating Positive Expiratory Pressure device）
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Sleep Apnea, Obstructive, Hypotonia
Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia
Children with hypotonic upper airway obstruction have a high prevalence of severe obstructive sleep apnea, which if not treated has significant clinical consequence.
- Conditions
- Sleep Apnea, Obstructive, Hypotonia, Child, Only
- Trial name
- ssNPA (NCT04846400)
- Testing
- ssNPA
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Michigan
Turbinate Hypertrophy, Adenoidectomy
Adenoidectomy With or Without Partial Inferior Turbinectomy for Pediatric Nasal Obstruction
Nasal obstruction is a common problem in children and is frequently caused by adenoid hypertrophy with concomitant inferior turbinate hypertrophy, leading to sleep-disordered breathing and reduced quality of life.
- Conditions
- Turbinate Hypertrophy, Adenoidectomy, Adenoid Hypertrophy, Turbinate Surgery
- Trial name
- NCT07745868
- Testing
- adenoidectomy, Adenodiectomy and bilateral partial infeiror turbienctomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Acute Rhinitis, Nasal Obstruction
Safety and Performance Assessment of the Decongestant Seawater Spray Pocket Valve Enriched With Essential Oils in Patients With Acute Rhinitis Associated With Nasal Obstruction: "DEVALPO"
The purpose of this pre-market clinical investigation is to assess the safety and the performance of decongestant seawater spray pocket valve enriched with essential oils by Gilbert Laboratories.
- Conditions
- Acute Rhinitis, Nasal Obstruction, Rhinosinusitis, Rhinopharyngitis
- Trial name
- DEVALPO (NCT05494346)
- Testing
- Measurement of peak nasal flow.
- Where
- 5 sites in France
- Volunteers
- 101 people
- Sponsor
- Laboratoires Gilbert
Nasal Congestion
A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold
The study will evaluate the safety and efficacy of the study medical device plus standard of care versus standard of care in subjects between 3 and 48 months (inclusive) presenting symptoms of a common cold.
- Trial name
- NCT05365789
- Testing
- Blocked Nose Baby nasal spray, Standard of care
- Where
- Poland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Hypotonia, Muscle, Obstructive Sleep Apnea
Long-term Evaluation of Nasopharyngeal Airway in Hypotonia
This research is studying the long term use of a nasal airway device (self-supporting nasopharyngeal airway; "ssNPA") in children with hypotonic upper airway obstruction to learn about its effectiveness and tolerability as a…
- Conditions
- Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
- Trial name
- NCT06614582
- Testing
- Self-Supporting Nasopharyngeal Airway (ssNPA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Nasal Congestion
Efficacy and Safety of Pediatric Drugs in Nasal Congestion
The purpose of this study is to evaluate the efficacy of the Naridrin in improving nasal congestion.
- Trial name
- NCT02601235
- Testing
- Naridrin, Afrin
- Where
- Brazil
- Volunteers
- 292 people
- Sponsor
- EMS
Nasal Obstruction, Common Cold
Observational Study of RHINOSEDAL in Acute Nasal Obstruction
This prospective, multicenter, national, observational, non-interventional post-market clinical follow-up study evaluates the performance and safety of RHINOSEDAL in children and adults presenting with acute nasal obstruction…
- Conditions
- Nasal Obstruction, Common Cold, Allergic Rhinitis, Non-allergic Rhinitis
- Trial name
- RHINOSEDAL (NCT07620522)
- Testing
- RHINOSEDAL
- Where
- France
- Volunteers
- 126 people
- Sponsor
- Laboratoires Elerte
Adenoids
Nasonex (Mometasone Furoate Nasal Spray) in Adenoids Hypertrophy in Children (P04367)
To document the short term \& long term effect of treatment with Nasonex (mometasone furoate nasal spray) in moderate to severe adenoids hypertrophy (which cause > 50% obstruction of the posterior choanae).
- Trial name
- NAHCh (NCT01098071)
- Testing
- mometasone furoate nasal spray
- Volunteers
- 34 people
- Sponsor
- Organon and Co
Apnea, Airway Obstruction, Nasal
Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion
Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least.
- Conditions
- Apnea, Airway Obstruction, Nasal, Mandible Small, Maxillary Hypoplasia
- Trial name
- NCT04190953
- Testing
- Twin block then Hyrax, Hyrax then Twin block
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Nasal Obstruction, Rhinoplasty
Inferior Turbinate Surgery in Rhinoseptoplasty: a Randomized Clinical Trial With Quality of Life Outcomes
The purpose of this study is to determine whether inferior turbinate surgery during rhinoseptoplasty is effective in improving quality of life and acoustic rhinometry outcomes.
- Conditions
- Nasal Obstruction, Rhinoplasty, Rhinoseptoplasty, Turbinate Surgery
- Trial name
- NCT01457638
- Testing
- Inferior turbinate surgery, No iInferior turbinate surgery
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Seasonal Allergic Rhinitis
A Phase III Efficacy Study of the Symptomatic Treatment of Seasonal Allergic Rhinitis With Bilastine
The objective of the study was to determine the efficacy and tolerability of 20 mg of Bilastine, compared to Desloratadine and placebo for the treatment of Seasonal Allergic Rhinitis.
- Trial name
- NCT01108783
- Testing
- Bilastine, Desloratadine
- Volunteers
- 720 people
- Sponsor
- Faes Farma, S.A.
Cough, Sore Throat
A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to Influenza
A Phase 3, multicenter, randomized, double-blind, controlled study to evaluate the efficacy and safety of peramivir administered intravenously in addition to standard of care compared to standard of care alone in adults and…
- Conditions
- Cough, Sore Throat, Nasal Congestion, Headache
- Trial name
- NCT00958776
- Testing
- Peramivir+SOC
- Where
- 196 sites in United States, Argentina and 21 more
- Volunteers
- 405 people
- Sponsor
- BioCryst Pharmaceuticals
Seasonal Allergic Rhinitis
Evaluation of the Beneficial Effects of a Nasal Spray of Resveratrol in Children With Seasonal Allergic Rhinitis
The aim of this study is to evaluate whether treatment with a nasal spray based on resveratrol has some benefit in patients with seasonal allergic rhinitis, mild, moderate, or severe.
- Trial name
- NCT02130440
- Testing
- Resveratrol nasal spray
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Campania Luigi Vanvitelli
Nasal Congestion, Nursing
Effects of Different Nasal Irrigation Methods on Pain Level, Crying and Procedure Times in Nasal Congestion in Infants
This study aimed to evaluate the effects of different nasal irrigation (NI) methods for relieving nasal obstruction on pain, crying and procedure times, and physiologic parameters in infants with acute upper respiratory tract…
- Trial name
- NCT06691620
- Testing
- Nasal irrigation with isotonic saline, Nasal irrigation with hypertonic saline, Nontraumatic nasopharyngeal aspiration
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University