Clinical trials: Negative-Pressure Wound Therapy
Pressure Sores
Effect of Negative Wound Pressure on P.S
This study will compare the NPWT using the NPD to the conventional wound dressing and specifically evaluating (i) reduction of wound surface area and depth, (ii) removal of slough and formation of granulation tissue
- Trial name
- NCT06243328
- Testing
- negative wound pressure therapy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Wound Healing
Comparison of Wound Healing Duration Between Vacuum-Assisted Closure (VAC) and Conventional Dressings
This randomized controlled trial will compare vacuum-assisted closure (VAC) therapy with conventional wound dressings for the treatment of open contaminated and dirty wounds.
- Trial name
- VAC-WOUND (NCT07832162)
- Testing
- Vacuum-Assisted Closure (VAC) Therapy Description:, Conventional Wound Dressing
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Postoperative Wound Complications
Negative Pressure Wound Therapy in Cesarean Section
The investigators propose a prospective, randomized trial evaluating the use of negative pressure wound therapy (NPWT) with high risk obstetrical patients.
- Trial name
- NPWTCS (NCT02289157)
- Testing
- Negative pressure wound therapy
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Metastatic Disease, Spinal Cord Injury
Negative Pressure Wound Therapy vs. Sterile Dressing for Patients Undergoing Thoracolumbar Spine Surgery
The purpose of this study is to determine if the use of the Prevena™ System decreases the rate of subcutaneous seroma, superficial wound dehiscence and infection.
- Conditions
- Metastatic Disease, Spinal Cord Injury, Spinal Degeneration, Spinal Deformity
- Trial name
- NCT03632005
- Testing
- Vacuum Assisted Closure, Sterile dressing
- Where
- Canada
- Volunteers
- 550 people
- Sponsor
- John Street
Post Traumatic Skin Loss
Negative Pressure Wound Therapy in Traumatic Skin Loss
Assessment of the effectiveness of negative pressure wound therapy on post-traumatic wounds, as regard to : The period of granulation tissue formation. The infection rate in NPWT in comparison to conventional dressing.
- Trial name
- NCT05653297
- Testing
- Vacuum-Assisted Closure
- Volunteers
- 50 people
- Sponsor
- Assiut University
Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers
Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds
Use of a motorized waterjet to debride wounds to improve healing outcomes.
- Conditions
- Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers, Pressure Injuries, Traumatic Wounds and Injuries
- Trial name
- NCT07653165
- Testing
- Motion NPWT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- West Boca Center for Wound Healing
Wounds and Injuries
Effect of Regulated Oxygen-Enriched Negative Pressure Therapy (RO-NPT) On Soft Tissue Wound Repair
The investigators believe that regulated oxygen-enriched negative Pressure Therapy (RO-NPT) will be beneficial in the reduction or elimination of anaerobic infection in hard-to-heal soft tissue wounds.
- Trial name
- NCT02357628
- Testing
- Wound treatment with RO-NPT, Wound Irrigation
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hillel Yaffe Medical Center
to See Whether Negative Pressure Wound Therapy Decreases Wound Infections.
Negative Pressure Wound Therapy - A Multi-Centered Randomized Control Trial
Children with neuromuscular disorders such as cerebral palsy, children with kyphosis and post-traumatic scoliosis have higher infection rates after scoliosis surgery than healthy children who undergo scoliosis surgery.
- Trial name
- NPWT (NCT02790385)
- Testing
- Negative Pressure Wound Therapy, Standard Gauze Treatment
- Where
- Canada
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Wounds and Injuries
Addition of Negative Pressure Wound Therapy to Standard Gauze Dressings for Acute Wounds in a Limited-Resource Setting
The worldwide prevalence of open wounds is estimated to be approximately 200 million per year. Negative Pressure Wound Therapy (NPWT), the application of a controlled vacuum to an open wound cavity, has been clinically…
- Trial name
- NCT02479542
- Testing
- Standard Gauze Dressing, WiCare NPWT dressing
- Sponsor
- Stanford University
Infection
Salvage of Infected Cardiovascular Implantable Electronic Devices (CIED) by Localized High-dose Antibiotics
Following previous positive experience with regulated CITA-RNPT of infected CIEDs, we suggest increasing the number of recruited patients and that CITA-RNPT can be administered prophylactically to patients prior to replacement of…
- Trial name
- NCT01770067
- Testing
- CITA-RNPT, Extraction of infected CIED
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hillel Yaffe Medical Center
Pilonidal Sinus, Wound Heal
PILONIDAL SINUS: CONVENTIONAL CARE VERSUS NEGATIVE PRESSURE THERAPY.
Pilonidal Sinus PS is a prevalent disease in young patients. There is currently no consensus on the surgical treatment of choice.
- Trial name
- SINUS-TPN (NCT05474911)
- Testing
- Negative pressure therapy, Conventional wound care
- Where
- Spain
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Sebastiano Biondo
Surgical Flap, Negative-Pressure Dressings
The Negative Pressure Wound Therapy in Flap Enhancement: Clinical Evaluation Study
The goal of this study is to compare the clinical outcomes of using NPWT dressing versus conventional dressing in improving flaps outcome
- Trial name
- NCT06080958
- Testing
- NPWT, Conventional dressing
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Wounds
Negative Pressure Wound Therapy With the Engenex™-Pump and Bio-Dome™ Dressing, an Evaluation
Negative pressure wound therapy (NPWT) has become a powerful tool in wound bed preparation of complex wounds and is routinely used in various disciplines, including general surgery and plastic surgery.
- Trial name
- NCT01107821
- Testing
- Engenex™ pump and Bio-Dome™ Wound Dressing
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University Hospital, Ghent
Negative Pressure Wound Therapy, Cesarean Section; Infection
The Invia Motion at Cesarean Study
To assess patient centered outcomes of the Medela INVIA Motion prophylactic NPWT system at cesarean delivery.
- Trial name
- NCT04365452
- Testing
- Invia Motion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Negative-Pressure Wound Therapy
Regulated Negative Pressure-Assisted Wound Therapy Device
Regulated negative pressure-assisted wound therapy (RNPT) is regarded as a gold standard technology for treatment of various chronic and acute wounds. The investigators plan to evaluate the efficacy and ease of use of this device.
- Trial name
- NCT01603901
- Testing
- Regulated Negative Pressure-Assisted Wound Therapy Device
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Hillel Yaffe Medical Center
Wound Infection, Wound Surgical
Efficacy of Negative Pressure Wound Closure Therapy by PICO System in Prevention of Complications of Femoral Artery Exposure
Evaluate negative pressure wound closure therapy by PICO system in Prevention of complications of femoral artery exposure.
- Trial name
- NCT04453319
- Testing
- Femoral Wound Closure and dressing
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Open Abdomen, Temporary Abdominal Closure Mechanisms
Open Abdomen: Vacuum Pack Versus Sylo Bag and Mesh Protocol
The open abdomen is a valid and accepted surgical tactic for the trauma and acute care patient. There have been many mechanisms described for its management, but the most accepted strategy is the vacuum pack.
- Trial name
- NCT01864590
- Testing
- Vacuum Pack, Double Sylo Bag - Mesh Protocol
- Where
- Colombia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Breast Reconstruction
Negative Pressure in PAP Donor Sites
A retrospective chart review will be conducted to identify patients who received breast reconstruction using free profunda artery perforator (PAP) flap by the investigators from January 2015 to August 2021.
- Trial name
- NCT05491473
- Testing
- Closed incisional negative pressure wound therapy (iNPWT) system
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Chang Gung Memorial Hospital
Surgical Site Infection, Complication,Postoperative
Study to Analyze the Surgical Site Infections in a Group of Patients Who Were Randomly Applied a Negative Pressure Therapy Dressing Versus Conventional Dressing
Surgical site complications generate a series of consequences that prolong hospital stay, increase interventions and procedures, and consequently considerably increase healthcare costs.
- Conditions
- Surgical Site Infection, Complication,Postoperative, Surgical Wound Infection, Surgical Complication
- Trial name
- NCT05455801
- Testing
- negative preassure wound therapy
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Hospital Universitario Central de Asturias
Wounds
Simplified Negative Pressure Wound Therapy
The objective of this study is to implement a simplified Negative Pressure Wound Therapy (sNPWT) device in a low resource setting.
- Trial name
- NCT01339429
- Testing
- simplified negative pressure wound therapy device (Wound Pump device)
- Where
- 2 sites in Rwanda
- Volunteers
- 41 people
- Sponsor
- Brigham and Women's Hospital