Clinical trials: Neurodevelopmental Disorders
EEG
Behavioural and Physiological Measures of Young Students With Dyslexia
The proposed is reading intervention study to track neural changes in the brain. Students with dyslexia will participate in a reading study.
- Trial name
- NCT05376696
- Testing
- Set For Variability, Current Best Practices
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University
Insomnia, Attention Deficit Hyperactivity Disorder
Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia
A multicenter study to evaluate the safety of eszopiclone in children (6 11 years of age, inclusive) and adolescents (12 17 years of age, inclusive) with attention deficit/hyperactivity disorder (ADHD) associated insomnia.
- Trial name
- NCT00857220
- Testing
- eszopiclone
- Where
- 89 sites in United States
- Volunteers
- 304 people
- Sponsor
- Sumitomo Pharma America, Inc.
Cerebral Visual Impairment
Neurodevelopmental Outcomes in Cerebral Visual Impairment
Cerebral visual impairment (CVI) is one of the leading causes of pediatric visual impairment and negatively impacts the development of motor, language, and cognitive skills.
- Trial name
- CVI-ND (NCT07212010)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Schizophrenia, Bipolar Disorder
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
This is a multicenter, global, 26-week, open-label study to assess the safety and tolerability of lumateperone in pediatric patients with schizophrenia, bipolar disorder or autism spectrum disorder.
- Conditions
- Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder
- Trial name
- NCT06229210
- Testing
- Lumateperone
- Where
- 65 sites in United States, Colombia and 1 more
- Volunteers
- 300 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Attention Deficit Disorder With Hyperactivity
Neuroimaging of the Effects of Concerta in the Treatment of ADHD
A number of brain regions have been down to be altered in both structure and function in patients with ADHD, including prefrontal cortex, anterior cingulate, caudate and cerebellum.
- Trial name
- NCT00778310
- Testing
- methylphenidate-OROS
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Sickle Cell Disease, Attention Deficit
Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease
Children with sickle cell disease (SCD) exhibit significantly reduced cognitive functioning (often difficulties with attention) compared to peers and siblings without SCD.
- Conditions
- Sickle Cell Disease, Attention Deficit, Cognitive Deficit in Attention
- Trial name
- ACT (NCT05099874)
- Testing
- EndeavorRx
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's National Research Institute
Attention Deficit Hyperactivity Disorder
Mobile Behavioral Parent Training for Childhood ADHD: Pilot Trial
The goal of the study is to develop and pilot a personalized behavioral parent training intervention for caregivers of children with attention deficit hyperactivity disorder.
- Trial name
- NCT05955274
- Testing
- Mobile Behavioral Parent Training (mBPT), Just-in-time intervention: Parenting Strategies
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Florida International University
Autism, Autism Spectrum Disorder
Environmental Influence on Mental Illness Via Modifications of Genomes and Metabolomes in Adolescents With Autism
The aim of the study is to enrich the understanding of the physiological mechanisms that predispose autistic adolescents to mental illness.
- Trial name
- ENIGMA-I (NCT06299618)
- Where
- 3 sites in Ireland, Romania and 1 more
- Volunteers
- 400 people
- Sponsor
- University College Cork
Attention Deficit Disorder With Hyperactivity, Behavioral Insomnia of Childhood
Effects of Evening Dose of Immediate Release Methylphenidate on Sleep in Children With ADHD
Over 10% of children in the United States are diagnosed with ADHD, and nearly half of these children have moderate to severe impairments in sleep, further exacerbating their already impaired academic, emotional and social…
- Trial name
- NCT02638168
- Testing
- Immediate Release Methylphenidate
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Milton S. Hershey Medical Center
Autism Spectrum Disorder (ASD, Dental Health
The Effect of Peer Video Modeling and 3D Jaw Video Modeling Training on Oral Health and Toothbrushing Skills in Children With Autism
This study was conducted to improve the oral hygiene habits of children with Autism Spectrum Disorder (ASD) and to compare the effects of peer video modeling and three-dimensional (3D) jaw model simulation methods.
- Conditions
- Autism Spectrum Disorder (ASD, Dental Health, Oral Hygiene, Oral Health, Pediatric Nursing
- Trial name
- RCT (NCT07492810)
- Testing
- Peer video modeling, 3D jaw video modeling
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ministry of Health, Turkey
ADHD, Parenting
Treating Parents With ADHD and Their Young Children Via Telehealth: A Hybrid Type I Effectiveness-Implementation Trial
This study will compare the effectiveness of combined parental stimulant medication and behavioral parent training (BPT) versus BPT alone on child ADHD-related impairment (primary outcome), child ADHD and externalizing symptoms…
- Trial name
- TPAC (NCT04240756)
- Testing
- Behavioral Parent Training, Extended release mixed amphetamine salts (MAS)
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- University of Maryland, College Park
Autism, Asperger's Syndrome
Computer- Assisted Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
This study will examine the efficacy of a computerized cognitive behavioral therapy (CCBT) program for children with anxiety and autism spectrum disorders.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- CCAL (NCT01565629)
- Testing
- Computer assisted cognitive behavioral therapy.
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anorexia Nervosa, Autism Spectrum Disorder
Characteristics of Autism Spectrum Disorder in Minors With Anorexia Nervosa in Remission
With this investigation, researchers wil look for a link between the appearance of anorexia nervosa and autism spectrum disorders in minors.
- Trial name
- NCT04095741
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- Universitair Ziekenhuis Brussel
Autism, Autism Spectrum Disorder
A Lead-in Study Evaluating Efficacy of GuessWhat Mobile App Therapy for Children With Autism
The following study aims to assess the efficacy, safety data, and best outcome measurements of the mobile game platform, GuessWhat, in delivering behavioral therapy to children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04739982
- Testing
- GuessWhat Mobile App
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Stanford University
Preterm Birth, Breast Milk Expression
Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development
This study is a randomized trial comparing 2 methods of human milk fortification for preterm infants in the neonatal intensive care unit (NICU).
- Conditions
- Preterm Birth, Breast Milk Expression, Nutrition Disorder, Infant, Brain Development Abnormality
- Trial name
- NCT03977259
- Testing
- Individually targeted fortification
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Brigham and Women's Hospital
Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders
Auditory and Visual Noise as Possible Non-pharmacological Treatment of ADHD in School Children
The goal of this study is to compare the influence of visual and auditory white noise on performance in children with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT06057441
- Testing
- Auditory noise stimulation, Visual noise stimulation
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Region Skane
Emotion Regulation, Autism Spectrum Disorder
Equine-assisted Therapy for Therapy-resistant Adolescents With Autism Spectrum Disorders, a Replicated AB-design
The purpose of this study is to assess the (cost)effectivity of Equine assisted Therapy in adolescents with Autism Spectrum disorders.
- Conditions
- Emotion Regulation, Autism Spectrum Disorder, Adolescent - Emotional Problem
- Trial name
- NCT05200351
- Testing
- Equine assisted Therapy (EAT)
- Where
- 3 sites in Netherlands
- Volunteers
- 35 people
- Sponsor
- Karakter Kinder- en Jeugdpsychiatrie
Epilepsy, Seizure Disorder
Epilepsy Learning Healthcare System (ELHS)
The Epilepsy Learning Health System (ELHS) is a quality improvement and research network to improve outcomes for people with epilepsy.
- Conditions
- Epilepsy, Seizure Disorder, Neurologic Disorder, Rare Diseases
- Trial name
- ELHS (NCT06265103)
- Testing
- Clinical care and quality improvement
- Where
- 13 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- Epilepsy Foundation of America
Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder
Evaluating the Validity of a Genetic Risk Assessment Tool in Identifying Autism Spectrum Disorder
There are three purposes to this study. The first purpose is to evaluate the value of a genetic test in determining risk for autism spectrum disorder.
- Conditions
- Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder, Developmental Delay
- Trial name
- NCT01452061
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Thomas W. Frazier, Ph.D
Autism Spectrum Disorder, Autism
Genetic Contributions to Autism Spectrum Disorders
This study is working towards gaining a better understanding of the genetic and environmental factors involved in autism spectrum disorders (ASD), which includes autism, pervasive developmental disorder (PDD), and Asperger's…
- Conditions
- Autism Spectrum Disorder, Autism, Asperger's Syndrome, Pervasive Developmental Disorder
- Trial name
- NCT01160783
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Boston Children's Hospital
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