Clinical trials: Neurodevelopmental Disorders
Autistic Disorder
Building Social Skills With Interdisciplinary Process Drama in ASD
This is a one group pre-post feasibility study of an interdisciplinary (theatre, Occupational Therapy (OT) and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT03536351
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Utah
Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD)
L-theanine and Paraxanthine for Cognitive Improvement in Adults With ADHD and ASD
This pilot study will test whether combining L-theanine and paraxanthine improves sustained attention, inhibitory control, and overall cognition in adults with ADHD and ASD.
- Trial name
- NCT07189442
- Testing
- L-theanine and paraxanthine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Texas Tech University Health Sciences Center
Development Delay, Child Development
Psychological Correlates of Developmental Delays in Preschool Children
The goal of this observational study is to investigate perinatal, cognitive, linguistic and social-emotional correlates of developmental delays of preschool children.
- Conditions
- Development Delay, Child Development, Social Functioning, Speech Delay
- Trial name
- NCT07420829
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
ADHD, Parenting
Helping Toddlers and Parents Together
Using stakeholder feedback (i.e., behavioral health providers \& caregivers), the goal of this study is to develop a behavioral parenting program that focuses on both parent mental health and parenting for parents of toddlers…
- Trial name
- NCT04864808
- Testing
- Behavioral Parent Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Autism Spectrum Disorder, Anxiety
Open-label Pilot Study Synbiotic Treatment for Autism Spectrum Disorder
The objective of this study is to conduct a open-label pilot study evaluating the feasibility, tolerability and preliminary efficacy of a 12-week course of synbiotic in improving anxiety symptoms in children with ASD.
- Trial name
- NCT06126185
- Testing
- 12-week course of synbiotic
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Autism, Autism Spectrum Disorder
A Study of Esomeprazole in Children With Autism
Autism is a pervasive developmental disorder characterized by core deficits in social behavior and communication and the presence of repetitive/stereotyped behaviors.
- Trial name
- NCT03866668
- Testing
- Esomeprazole
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Autistic Disorder, Seizures
Treatment Resistant Epilepsy and N-Acetyl Cysteine
This is a study to find out whether the dietary amino acid supplement, N-acetyl cysteine (NAC) is helpful in reducing the frequency of seizures in children with autism and comorbid epilepsy whose seizures are not responding well…
- Conditions
- Autistic Disorder, Seizures, Irritability
- Trial name
- TRE-NAC (NCT02054949)
- Testing
- N-Acetyl Cysteine (NAC)
- Where
- United States
- Sponsor
- Nationwide Children's Hospital
Autistic Disorder, Autism Spectrum Disorder
Training Attention and Eye Movement in ASD
Current therapies for autism target social and language behaviors, but due to the high-level nature of these skills any improvement rarely extends beyond the targeted behavior.
- Trial name
- NCT02403817
- Testing
- Cognitive Training, Eye Motor Training, Hand Motor Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Motor Coordination or Function; Developmental Disorder
A Multiple Baseline Design Study to Investigate the Effectiveness of OT-SI Using an Intensive Intervention Model
The investigators hypothesize that children completing 30 sessions of occupational therapy using a sensory integration approach (OT-SI) will demonstrate positive changes in outcome measures related to motor coordination…
- Trial name
- NCT03355417
- Testing
- OT-SI
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Virginia Commonwealth University
ADHD
Impact of A Multidimensional Health Education Program on Attention Deficit Hyperactivity Disorder (ADHD)
To measure the impact of a multidimensional health education program on patients' adherence to the healthy life style and behavioral therapy , and to correlate it with severity of ADHD symptoms
- Trial name
- ADHD (NCT06406335)
- Testing
- Health education program
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dyslexia, Visual Attention Span Deficit
Visual Attention Span Mobilisation for Dyslexia
The aim of the study is to evaluate the efficiency of the medical device MAEVAD in improving the reading skills of children with dyslexia.
- Trial name
- NCT05201235
- Testing
- MAEVAD, DeCaLigne
- Where
- 55 sites in France
- Volunteers
- 74 people
- Sponsor
- Humans Matter
Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC)
Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics
This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT).
- Conditions
- Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC), Crohn Disease (CD), Irritable Bowel Syndrome (IBS)
- Trial name
- NCT07261826
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Chen QiYi
Developmental Coordination Disorder
Tai Chi-muscle Power Training for Primary School Children With Developmental Coordination Disorder
Objectives: To compare the effectiveness of Tai Chi-muscle power training (TC-MPT), Tai Chi (TC) alone, muscle power training (MPT) alone, and usual care (as a control) for improving the limits of stability (LOS) of balance…
- Trial name
- NCT03598478
- Testing
- TC-MPT, TC, MPT
- Where
- Hong Kong
- Volunteers
- 156 people
- Sponsor
- The University of Hong Kong
Attention Deficit Hyperactivity Disorder
Atomoxetine to Treat Korean Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to provide information regarding the relative effectiveness of three different atomoxetine doses in the treatment of Korean children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD)
- Trial name
- NCT00568685
- Testing
- Atomoxetine Hydrochloride
- Where
- 3 sites in South Korea
- Volunteers
- 153 people
- Sponsor
- Eli Lilly and Company
Attention Deficit/Hyperactivity Disorder
A Trial of Centanafadine Efficacy and Safety in Children With Attention-deficit/ Hyperactivity Disorder (ADHD)
This trial will be conducted to evaluate the efficacy of centanafadine once daily (QD) extended release (XR) versus placebo in the treatment of child subjects (4 to 12 years, inclusive) with ADHD.
- Trial name
- NCT05428033
- Testing
- centanafadine capsule
- Where
- United States
- Volunteers
- 574 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Tic Disorders
Clinical Efficacy and Change of Life Quality Through Using the Comprehensive Behavioral Intervention Treatment for Tics
Study on the clinical efficacy and change of life quality through using the Comprehensive Behavioral Intervention Treatment for Tics (CBIT)
- Trial name
- NCT04765085
- Testing
- comprehensive behavioral intervention therapy (CBIT), Aripiprazole 5Mg Oral Tablet
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder
Movement-Based Digital Game Intervention for Children With Autism Spectrum Disorder
The goal of this study is to learn if movement-based digital games can help improve motor skills in children aged 6-10 years with Autism Spectrum Disorder (ASD).
- Trial name
- MBDG-ASD (NCT07779525)
- Testing
- Movement-Based Digital Games
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Insomnia, ADHD
Efficacy of Cognitive Behavioural Therapy for Insomnia and Bright Light Therapy in Adolescents With ADHD, Insomnia, and Evening Chronotype
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by persistent inattention, hyperactivity, and impulsivity.
- Conditions
- Insomnia, ADHD, Eveningness, Chronotype
- Trial name
- NCT07767617
- Testing
- CBT-I with Bright Light Group
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
ADHD
Impact of Short and Mistimed Sleep on Adolescents With ADHD: The Adolescent Attention and Circadian Timing Study
Many adolescents go to bed late and wake up early for school. Science is only beginning to understand how sleep schedules can affect them.
- Trial name
- AACT (NCT07684417)
- Testing
- Aligned sleep extension, Misaligned sleep extension
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism or Autistic Traits
Relation Between Autistic Features and Fine Motor Abilities in Children With Autism Spectrum Disorder
deleyed fine motor skills are currently considered a as clinical manifestation of autism spectrum disorder, should be assessed due to their high incidence and considerable influence on life quality functional activity
- Trial name
- NCT07858617
- Testing
- assessment
- Volunteers
- 80 people
- Sponsor
- Cairo University
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