Clinical trials: Neurodevelopmental Disorders
Motor Skills Disorders
Taekwondo for Children With Developmental Coordination Disorder
Objectives: To evaluate the effects of a novel adapted Taekwondo (TKD) training programme on skeletal development and motor proficiency in pre-pubertal children with developmental coordination disorder (DCD).
- Trial name
- NCT02635711
- Testing
- Adapted Taekwondo training, Control
- Where
- Hong Kong
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorders
Cortical Metrics Assessment Outcome Measure Development in Autism With Memantine Treatment
Specific Aim 1: Obtain proof of concept evidence that cortical metrics will change in response to treatment with Memantine extended release (XR)®, an agent that modulates n-methyl d-asptartate (NMDA) receptor activation, in…
- Trial name
- NCT02353130
- Testing
- Memantine-XR
- Sponsor
- University of North Carolina, Chapel Hill
Autism
CBT for Youth With Autism and Emotional/Behavioral Needs in Community Care Settings
This study is a 4-year randomized, controlled trial comparing cognitive behavioral therapy (CBT) to usual clinical care for children (aged 6-14 years) with autism and emotional dysregulation (e.g., irritability, anxiety).
- Trial name
- CYAN (NCT05031364)
- Testing
- Behavioral Interventions for Anxiety in Children with Autism (BIACA), Treatment-as-Usual Supplemented by Internet-Based Self-Instruction (MEYA)
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder, Child Development Disorders, Pervasive
Social Robots and Board Games for Children With Autism Spectrum Disorder
This pilot randomized controlled trial evaluates the effectiveness of combining social robot-assisted intervention with physical board games to improve socio-emotional skills in children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT07775937
- Testing
- Social Robot-Assisted Board Game Intervention, Conventional Occupational Therapy
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Obesity, Binge-Eating Disorder
Emotion Regulation and Binge Eating in Youth With Obesity
This study will investigate neural activation patterns in emotion- and cognition-related brain regions during an emotion regulation task involving cognitive reappraisal, and their associations with age and pubertal status, among…
- Trial name
- NCT02783872
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
ADHD, Child, Only
A Randomized Controlled Study of Family Based EF Training for Schoolage Children With ADHD
The goal of this study is to provide a new treatment approach for schoolage children with ADHD, which could facilitate the EF developing well to achieve better outcome.
- Trial name
- NCT05025501
- Testing
- Family based Executive Function Training
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Sleep Problems
Assessment of the Pharmacokinetics of Circadin® in Children With Neurodevelopmental Disorders and Sleep Disturbances
There is increasing evidence that chronic sleep disorders in children with autism spectrum disorder (ASD), Angelman Syndrome (AS) and Smith-Magenis syndrome (SMS) are associated with disturbed melatonin secretion and melatonin…
- Trial name
- NCT01903681
- Testing
- Circadin 2 mg, Circadin 10 mg
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
ADHD, Cancer
Pilot Study Of Primary And Secondary Attention-Deficit/Hyperactivity Disorder Among Survivors Of Childhood Cancer
This is a pilot study that will be an exploratory investigation of the rate of occurrence of ADHD/S-ADHD in adolescent cancer survivors.
- Trial name
- NCT01032811
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- St. Jude Children's Research Hospital
Attention Deficit Hyperactivity Disorder
Transcranial Magnetic Stimulation in Children With Attention Deficit Hyperactivity Disorder (ADHD). A Safety Study
Low frequency repetitive Transcranial Magnetic Stimulation(rTMS) is a safe and tolerable procedure in children with Attention Deficit Hyperactivity Disorder(ADHD); it also could be a complement to the treatment of patients with…
- Trial name
- NCT01052064
- Testing
- Transcranial Magnetic Stimulation
- Where
- Cuba
- Volunteers
- 20 people
- Sponsor
- International Center for Neurological Restoration, Cuba
Mathematics Disorder
Intervention for Low-performing First Graders in Mathematics
The aim of this study is to investigate the effect of an intervention program for low-performing first graders in mathematics. .
- Trial name
- NCT05709418
- Testing
- Intensiv support for first graders in Norway
- Where
- Norway
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ostfold University College
Autism Spectrum Disorders
Brain Mechanisms for Language Processing in Adolescents With Autism Spectrum Disorder
The main goal of our study is to find out why some people with Autism Spectrum Disorder (ASD) do not develop verbal abilities or remain minimally-verbal throughout adolescence and adulthood.
- Trial name
- BSL (NCT02700074)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Preterm Birth, Developmental Delay
The Alkmaar MLPTI Cohort Study: Outcomes at 9 Years
Objective of the study: To examine cognition, motor function, executive functions, speech and language development, behaviour, psychosocial functioning,academic achievement, physical morbidities and growth of MLPTI at the age of…
- Conditions
- Preterm Birth, Developmental Delay, Growth Delay
- Trial name
- NCT05990582
- Testing
- CBCL, SDQ, CCC-2-NL
- Where
- Netherlands
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Noordwest Ziekenhuisgroep
Attention Deficit Hyperactivity Disorder
An Open Label Phase I/II Study of the Safety and Dopamine Transporter Binding Properties of C-11 Altropane in Normal Human Subjects and in Subjects With ADHD
The primary objective of this study is to evaluate the Binding Potential in subjects with ADHD and adults without ADHD: the intent being to demonstrate that C-11 Altropane PET can be used to differentiate adults with ADHD from…
- Trial name
- NCT00302380
- Testing
- PET imaging using C-11 altropane as the ligand.
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder
ADZENYS XR-ODT™ in Children (4 to <6 Years) Diagnosed With Attention-deficit/Hyperactivity Disorder
This is a randomized, double-blind, flexible dose-titration, placebo-controlled, parallel-group study designed to evaluate the efficacy, safety, and tolerability of ADZENYS XR-ODT compared to placebo in children with ADHD.
- Trial name
- NCT07169162
- Testing
- ADZENYS XR-ODT
- Where
- United States
- Sponsor
- Aytu BioPharma, Inc.
Autism Spectrum Disorder
Effects of the Sherborne Developmental Movement Program on Motor Performance in Children With Autism Spectrum Disorders
The aim of this study was to investigate the effects of the Structured Sherborne Developmental Movement Program on sensory processing, motor performance and functional status in children with autism spectrum disorders.
- Trial name
- absent (NCT06766942)
- Testing
- structured sherborne developmental movement program with sensory-based occupational therapy program, sensory-based occupational therapy program group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Elif Dilan ATILGAN
Autism Spectrum Disorder
Early Socioemotional Intervention for Children With Autism Spectrum Disorder in Hong Kong and Mainland China
This study aims to develop a culturally-sensitive parent-training intervention to enhance socioemotional functioning of young children (aged 3-6) with Autism Spectrum Disorder (ASD) in Mainland China.
- Trial name
- NCT04658043
- Testing
- Intervention on socioemotional functioning
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- The University of Hong Kong
Mood Disorder, Mental Disorder Diagnosed in Childhood
A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation
Severe mood dysregulation (SMD) is a very common syndrome in children. Its symptoms include very severe irritability, including persistent anger and frequent outbursts, as well as distractibility, hyperactivity, and other…
- Conditions
- Mood Disorder, Mental Disorder Diagnosed in Childhood, Attention Deficit and Disruptive Behavior Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT00794040
- Testing
- Add-on citalopram following optimized methylphenidate
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder
Adapted Aquatic Exercise and Behavioral Outcomes, Flexibility, and Handgrip Strength in Children With Autism Spectrum Disorder
This randomized clinical trial studied whether an adapted aquatic exercise program could improve behavior and physical abilities in children with autism spectrum disorder (ASD).
- Trial name
- NCT07410897
- Testing
- Adapted Aquatic Exercise Program, Academic Instruction
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Autism Spectrum Disorder
Participation-based Intervention on Community Participation and Parent Empowerment for Children With ASD
Community participation of children with ASD is affected by child (including body function and personal factors), family and environmental factors.
- Trial name
- PBI-ASD (NCT03721913)
- Testing
- participation-based intervention
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung University
Autism Spectrum Disorders
Phenotypic and Genetic Factors in Autism Spectrum Disorders
The purpose of the study is to collect phenotypic (observable characteristics) and genetic information about individuals with Autism Spectrum Disorders (ASDs) and their families.
- Trial name
- NCT00910559
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Boston Children's Hospital
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