Clinical trials: Neurologic Complications
Premature Birth, Basic Learning Problem in Reading
Reading in Preterm and Full-term Children: Neural Basis and Prediction
The purpose of this study is to understand reading abilities of children born preterm: their cognitive profiles, the neural basis of good and poor reading abilities, and the behavioral and neural factors that predict persistent…
- Conditions
- Premature Birth, Basic Learning Problem in Reading, Child
- Trial name
- NCT01599546
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia
Palliative Care Needs of Children With Rare Diseases and Their Families
The palliative care needs of family caregivers of children with rare diseases and their children are largely unmet, including the need for support to prepare for future medical decision making.
- Conditions
- Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome
- Trial name
- FACE-Rare (NCT06938542)
- Testing
- Family Centered pediatric palliative care for family caregivers of children with rare diseases.
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Preterm, Assessment
GMA and Peri in Moderate-late Preterms
To analyze the relationship between the early diagnosis of cerebral palsy with the risk factors of this pathology in moderate and late premature infants
- Conditions
- Preterm, Assessment, Risk Factor, Cerebral Palsy
- Trial name
- NCT04073836
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Alzheimer Disease, Late Onset, Stroke
Explore the Sharing Model Intervene to Improve the Knowledge, Attitudes, Service Intentions and Service Start-up Effects of the Eight Major Non-cancer Disease End-stage Caregivers on Well-being and Palliative Care
Since September 1st, 2009, Taiwan has begun to pay attention to the care of patients with organ failure, dementia and the elderly, and brought eight of non-cancer terminal patients into health insurance subsidies to implement the…
- Conditions
- Alzheimer Disease, Late Onset, Stroke, Heart Failure, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT05407272
- Testing
- Health Education Manual, manual
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wen-Shiou Pan
Children, Pain Management
Cartoons and Reflexology for Postoperative Nausea, Pain, and Anxiety in Children
Preoperative anxiety arises as a physiological response of the body to stressors and is pathophysiologically associated with stimulation of the autonomic nervous system and increased catecholamine release (Durgut, 2021).
- Conditions
- Children, Pain Management, Nausea, Postoperative
- Trial name
- NCT07151131
- Testing
- Watching Cartoons, Reflexology
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Emergence Delirium, Strabismus
Methadone for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery
Strabismus surgery for children is a very common procedure, with a high incidence of emergence delirium in the recovery room. Pain is often implicated in delirium.
- Trial name
- NCT03778372
- Testing
- Methadone
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Urologic Surgical Procedures, Urinary Bladder, Neurogenic
Pediatric Urology Recovery After Surgery Endeavor (PURSUE)
The purpose of this research study is to evaluate an Enhanced Recovery After Surgery (ERAS) protocol in children and young adults undergoing urologic reconstructive surgery.
- Conditions
- Urologic Surgical Procedures, Urinary Bladder, Neurogenic, Urinary Bladder Diseases
- Trial name
- NCT03245242
- Testing
- Enhanced Recovery after Surgery, Historical usual surgical care
- Where
- 7 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Intubation; Difficult or Failed, Postoperative Pain
The Comparison of Direct Macintosh Laryngoscopy and HugeMed Video Laryngoscope for Nasotracheal Intubation in Children
Forty-four patients aged 4-10 years who applied to Aydın Adnan Menderes University Faculty of Dentistry for dental treatment under general anesthesia will be selected and divided into 2 groups by simple randomization.
- Trial name
- NCT05121597
- Testing
- HugeMed Videolaryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Adenotonsillectomy, Post-operative Analgesia
Non-opioids for Analgesia After Adenotonsillectomy in Children
The goal of this study is to determine if non-opioid pain control is a safe way to manage pain after adenotonsillectomy surgery in children.
- Conditions
- Adenotonsillectomy, Post-operative Analgesia, Opioid Use
- Trial name
- NCT03618823
- Testing
- Oxycodone, Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- David Chi, MD
Emergence Delirium
Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence agitation is commonly encountered after receiving inhalation anesthesia. This distressing phenomenon carries risks that are harmful to patients, caregivers and medical personnel.
- Trial name
- NCT06482125
- Testing
- Dexmedetomidine, Sevoflurane
- Where
- Indonesia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Pelita Harapan University
Postoperative Pain, Fear
Designing Animated Movie for Preoperative Period
Background: Using visual materials is effective in education to decrease children's pre-operative fear and post-operative pain. Children, especially those aged between 6 and 12 years, are interested in technology.
- Conditions
- Postoperative Pain, Fear, Surgery, Pain
- Trial name
- NCT04176822
- Testing
- Educational animated movie group, Documentary movie group
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ege University
Pain, Post-Operative Pain
Ibuprofen Extended-Release Dental Pain Study
The purpose of this study is to evaluate the efficacy and safety of multiple doses of Ibuprofen 600 mg Extended-Release Tablets in a study of dental pain following extraction of third molar teeth.
- Conditions
- Pain, Post-Operative Pain, Third Molar Extraction
- Trial name
- NCT00707057
- Testing
- Ibuprofen 600 mg Extended-Release Tablets
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- SCOLR Pharma, Inc.
Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism
Growing up With the Young Endocrine Support System (YESS!)
Transition from paediatric to adult endocrinology is a challenge for adolescents, families and doctors. Up to 25% of young adults with chronic endocrine disorders are lost to follow-up ('drop-out') once the young adult moves out…
- Conditions
- Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism, Growth Hormone Deficiency, Combined Pituitary Hormone Deficiency
- Trial name
- YESS (NCT04252001)
- Testing
- YESS! game, Snake '97, Transition-toolkit
- Where
- 7 sites in Belgium, Netherlands and 2 more
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- dr. Laura C. G. de Graaff-Herder
Necrotic Pulp, Postoperative Pain
Evaluation of Postoperative Pain After Using 3MIX-TATIN Versus Calcium Hydroxide Iodoform Paste In Necrotic Primary Molars Treated by Lesion Sterilization and Tissue Repair Therapy
The aim of the current study is to compare a newly introduced material which is a combination of triple mix antibiotics paste and anti-hyperlipidemia drug simvastatin, the new material is named 3MIX-TATIN \& will be compared to…
- Trial name
- 3-mixtatin (NCT03084601)
- Testing
- Calcium Hydroxide, Iodoform, paste, 3-mixtatin
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahmoud M Saadoon
Huntington Disease, Hereditary Breast and Ovarian Cancer
Genetic Risk: Whether, When, and How to Tell Adolescents
This study is being conducted to learn more about family communication of genetic risk information. Semi-structured interviews lasting up to one hour will be conducted with three populations: parent/child pairs at risk for…
- Conditions
- Huntington Disease, Hereditary Breast and Ovarian Cancer, Hereditary Cancer, Hereditary Non-polyposis Colon Cancer
- Trial name
- NCT03421327
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Impacted Third Molar Tooth
Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution.
- Trial name
- NCT03179813
- Testing
- Hydrocortisone, Control
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Emergence Agitation
Melatonin for Pediatric Emergence Agitation
efficacy of melatonin premedication on emergence agitation in children undergoing herniorrhaphy surgeries
- Trial name
- NCT05223010
- Testing
- Melatonin 5 MG/15 ML Oral Solution 0.05 mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.2mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.4mg/kg
- Where
- Egypt
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Preterm Birth, Developmental Delay
The Alkmaar MLPTI Cohort Study: Outcomes at 9 Years
Objective of the study: To examine cognition, motor function, executive functions, speech and language development, behaviour, psychosocial functioning,academic achievement, physical morbidities and growth of MLPTI at the age of…
- Conditions
- Preterm Birth, Developmental Delay, Growth Delay
- Trial name
- NCT05990582
- Testing
- CBCL, SDQ, CCC-2-NL
- Where
- Netherlands
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Noordwest Ziekenhuisgroep
Postoperative Pain, Emergence Delirium
Effect of Preoperative Fasting Duration on Postoperative Pain and Emergence Agitation in Pediatric Patients Undergoing Urogenital Surgery
This study aims to evaluate the effect of preoperative fasting duration on postoperative pain and emergence agitation in pediatric patients undergoing urogenital surgery.
- Conditions
- Postoperative Pain, Emergence Delirium, Emergence Agitation
- Trial name
- NCT07552259
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Trisomy 13, Trisomy 18
Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial
This prospective blinded study will assess the diagnostic capability of an informatics enhanced SNP based technology (Parental Support) to identify pregnant women who are carrying a fetus with an aneuploidy from fee floating DNA…
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Aneuploidy
- Trial name
- PreNATUS (NCT01545674)
- Testing
- Blood Draw
- Where
- 29 sites in United States, Canada and 4 more
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.