Clinical trials: Neuromuscular Function
Cerebral Palsy, Congenital
CIMT and BIMT Affect Functional Outcome in CP
The aim of this randomized controlled trial is to determine the effects of constraint induced movement therapy CIMT and BIM bimanual activities on functional outcome in hemiplegic CP.
- Trial name
- NCT04211623
- Testing
- Constraint induced movement therapy, Bimanual activities
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Hamstring Flexibility, Hamstring Muscle Tightness
Effects of Combining PNF With NMES in Young Football Players
Hamstring muscle injuries are common in sports like football and often lead to extended periods of inactivity. This study aims to compare the effects of two different stretching programs on hamstring flexibility, with a secondary…
- Trial name
- PNF+NMES (NCT07075497)
- Testing
- Neuromuscular electrical stimulation (NMES), Contract-Relax PNF (crPNF)
- Where
- Spain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Muscular Dystrophy, Duchenne, Ambulatory Care
Phase III Study of Idebenone in Duchenne Muscular Dystrophy (DMD)
The aim of this Phase III study was to assess the efficacy of idebenone on pulmonary function, motor function, muscle strength and quality of life in patients with DMD.
- Trial name
- DELOS (NCT01027884)
- Testing
- Idebenone
- Where
- 23 sites in United States, Austria and 8 more
- Volunteers
- 65 people
- Sponsor
- Santhera Pharmaceuticals
Obstetric; Injury
Modified Constraint Induced Movement Therapy in Children With Obstetric Brachial Plexus Injury
The aim of this study was to increase and improve the use of affected extremity in obstetric brachial plexus palsy children while restricting the use of less affected arm and the purpose was to improve the function, Range of…
- Trial name
- NCT05411731
- Testing
- Conventional physical therapy treatment, Constraint induced movement therapy
- Where
- Pakistan
- Volunteers
- 16 people
- Sponsor
- Riphah International University
Fibromyalgia, Irritable Bowel Syndrome
Genetics of Fibromyalgia
The Fibromyalgia Family Study identifies and collects blood samples from families with two or more members affected with Fibromyalgia Syndrome (FMS).
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome, Depression
- Trial name
- NCT00071162
- Where
- 4 sites in United States
- Volunteers
- 560 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Spinal Muscular Atrophy
Motor Function and Activity of Daily Life in Spinal Muscular Atrophy
This study will incorporate patients/ caregivers' perspectives to investigate the performance in daily activities of individuals with SMA and how it relates to their motor function abilities.
- Trial name
- NCT05931211
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy
Comparison of Constraint-Induced Movement Therapy And Bimanual Intensive Therapy Through Tele-rehabilitation For CP
Cerebral palsy is a neurological condition affecting movement and posture, caused by non-progressive brain disruptions occurring during fetal development.
- Trial name
- NCT06658275
- Testing
- Constraint-induced movement therapy, Hand Arm Bimanual Intensive Training -HABIT
- Volunteers
- 65 people
- Sponsor
- Riphah International University
Stroke, Drop Foot
Pairing Functional Electrical Stimulation (FES) and Volitional Effort Training Promotes Neuroplasticity and Motor Gain
The goal of the study is to explore the effect of combined training involving functional electrical stimulation (FES) of the ankle dorsal flexor with simultaneous maximal-effort voluntary contraction of the same muscle to correct…
- Trial name
- NCT02797886
- Testing
- FES + VOL, FES, VOL
- Volunteers
- 45 people
- Sponsor
- Kessler Foundation
Spinal Muscular Atrophy
Spinal Muscular Atrophy and Cardiac Autonomic Function
Respiratory dysfunction is the major cause of morbidity and mortality in patients with spinal muscular atrophy (SMA). Air stacking is a clearance airway technique frequently used but its effects on cardiac autonomic function in…
- Trial name
- NCT01522079
- Testing
- Air stacking manuever
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Children With Cerebral Palsy
Extracorporeal Shock Wave Therapy Versus Functional Electrical Stimulation on Spasticity, Function and Gait Parameters in Hemiplegic Cerebral Palsy
Objective: The purpose of this study will compare the effects of extracorporeal shock wave therapy (ESWT) versus functional electrical stimulation (FES) on spasticity, function and gait parameters in hemiplegic cerebral palsy…
- Trial name
- NCT03856905
- Testing
- Physical therapy program, Extracorporeal shock wave therapy, Functional electrical stimulation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Cerebral Palsy
The Effect of Botox on Children With Cerebral Palsy
Botulinum toxin injections are a common form of treatment for children with cerebral palsy to help reduce muscle tightness and help them walk without resorting to surgery.
- Trial name
- NCT00503620
- Testing
- Botulinum Toxin A
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Duchenne or Becker Muscular Dystrophy
Effectiveness of Aquatic Therapy in Children With Duchenne and Becker Muscular Dystrophy
The purpose of this study is ; to evaluate the effects of aquatic therapy applied in addition to conventional physical therapy on balance, functionality and quality of life in children with Duchenne and Becker muscular dystrophy.
- Trial name
- NCT06186310
- Testing
- Aquatic Therapy Group, Conventional Physical Therapy Group
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Stroke
Effects of SBMT Combined With NMES on UL Functions in Post Stroke Patients
The aim of this study to evaluate the effects of synergy-based motor therapy combined with neuromuscular electric stimulation on upper limb function on post stroke patients
- Trial name
- NCT07576465
- Testing
- Synergy-based motor therapy, Neuromuscular electrical stimulation, Conventional therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Spinal Muscular Atrophy (SMA), Neuromuscular Disease
Ultrasonographic Muscle Assessment and Functional Scales in Spinal Muscular Atrophy
This study aims to investigate the relationship between ultrasonographic muscle thickness measurement and echogenicity assessment with functional scales in children with spinal muscular atrophy (SMA).
- Trial name
- NCT06599606
- Testing
- Ultrasonographic Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Muscular Dystrophies, Muscular Dystrophy, Duchenne
A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
HOPE-2 is a double-blind clinical trial evaluating the safety and efficacy of a cell therapy called CAP-1002 in study participants with Duchenne Muscular Dystrophy (DMD).
- Conditions
- Muscular Dystrophies, Muscular Dystrophy, Duchenne, Muscular Disorders, Atrophic, Muscular Diseases
- Trial name
- HOPE-2 (NCT03406780)
- Testing
- CAP-1002
- Where
- 9 sites in United States
- Volunteers
- 20 people
- Sponsor
- Capricor Inc.
Facioscapulohumeral Muscular Dystrophy
Quantitative Assessment of Orofacial Muscle Function in FSHD
The goal of this study is to validate a new method for the assessment of orofacial muscles in FSHD affected individuals
- Trial name
- NCT06425445
- Testing
- Orofacial function assessment tests
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Mons
Duchenne Muscular Dystrophy
Correlation Between Functional Capacity and Functional Capability in Duchenne Muscular Dystrophy
This study investigates the correlation between assessments measuring functional capacity and functional capability in patients with Duchenne muscular dystrophy.
- Trial name
- NCT05249361
- Testing
- no intervention
- Where
- 2 sites in South Korea
- Volunteers
- 48 people
- Sponsor
- Samsung Medical Center
Spinal Muscular Atrophy
Responsiveness and Validation Study of MFM-20 in SMA Patients Treated With Nusinersen
The Motor Function Measure (MFM), a reliable tool assessing motor function and its progression in most neuromuscular diseases, is widely used in France in many teams.
- Trial name
- RetroNusiMFM (NCT04644393)
- Where
- 8 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Cerebral Palsy, Spastic
Neurodevelopmental Therapy for Spastic Cerebral Palsy
This study was conducted to find out the Effects of Neurodevelopment therapy (a rehabilitative program designed by Bobath) on Gross Motor Function and Postural Control in Children with Spastic Cerebral Palsy.
- Conditions
- Cerebral Palsy, Spastic, Diplegia, Spastic
- Trial name
- NDT (NCT05231538)
- Testing
- Neurodevelopmental therapy, Routine physical therapy
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- University of Lahore