Clinical trials: Nicotine
Tobacco Use Disorder
Tobacco Approach Avoidance Training for Adolescent Smokers-1
This is a two part study. Study 1 will compare Approach Avoidance Training (AAT) responses in smokers and nonsmokers in order to confirm that adolescent smokers experience cognitive bias towards tobacco-related stimuli.
- Trial name
- AAT-1 (NCT01625767)
- Testing
- AAT experiment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Growth Failure, Preterm Birth
Impact of Colostrum Oropharyngeal Immunotherapy on Postnatal Growth in Preterm Infants
The goal of this clinical trial is to ascertain whether oropharyngeal administration of colostrum contributes to postnatal growth in very preterm infants (those born before 32 weeks of gestation).
- Conditions
- Growth Failure, Preterm Birth, Microbiota
- Trial name
- IOCOIOPGIPI (NCT07082881)
- Testing
- Colostrum, Normal Saline
- Volunteers
- 220 people
- Sponsor
- Suqian First Hospital
Chronic Diarrhea, Persistent Vomitting
Pediatric GI Endoscopy at Assiut University
1. To evaluate the diagnostic role, and outcomes of upper and lower gastrointestinal (GI) endoscopy in identifying gastrointestinal disorders among infants and pediatric patients attending Assiut University Children Hospital. 2.
- Conditions
- Chronic Diarrhea, Persistent Vomitting, Gastrointestinal Bleeding, Dysphagia
- Trial name
- NCT07239934
- Testing
- Gastrointestinal Endoscopy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Tobacco Use and Smoking Behavior
Controlled Trial to Reduce Secondhand Smoke Exposure at Homes in Armenia
This study was designed to test the hypothesis whether a novel intervention that uses motivational interviewing along with immediate feedback and follow-up counseling calls is effective in educating the household members about…
- Trial name
- NCT01630356
- Testing
- in-person counseling, Demonstration of PM2.5 Pollution, Follow-up Counseling Calls
- Where
- Armenia
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Nicotine Dependence
Evaluation of Very Low Nicotine Content Cigarettes in Adolescent Smokers
The purpose of this study is to determine how reducing the level of nicotine in cigarettes may affect adolescent smoking behavior.
- Trial name
- NCT02587312
- Testing
- Very low nicotine content cigarettes, Standard nicotine content cigarettes
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Brown University
Nicotine Vaping, Nicotine Use Disorder
Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors
Use of vaping products (e.g., electronic nicotine delivery systems, e-cigarettes) has been increasing rapidly, particularly among teens and young adults.
- Trial name
- NCT05994209
- Testing
- quitSTART Mobile Application, Chatbot Feature in quitSTART Mobile Application
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Washington University School of Medicine
Growth Faltering, High Density Formula
The Efficacy of High Density Formula 1.5 kcal/ml or 1 kcal/ml On Catch Up Growth In Growth Faltering Children
High density calorie is an Oral Nutrition Supplement (ONS) which is a high calorie formula (High Density Formula) and suggested as nutritional therapy to assist children who are undernourished or undergoing growth faltering.
- Conditions
- Growth Faltering, High Density Formula, Catch Up Growth
- Trial name
- NCT06160765
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Universitas Airlangga
Nicotine Vaping
Kick-Nic! Youth Quit Vaping App
High school and middle school students who want to quit vaping will be randomized to receive the Kick-Nic! app or a control NCI website to determine the efficacy of the app for vaping cessation.
- Trial name
- NCT06662305
- Testing
- Kick-Nic! mobile phone application, NCI Quit Vaping website
- Where
- United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Yale University
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Vaping
Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents
Social media based intervention to support teens in their efforts to quit vaping.
- Trial name
- NCT04707911
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Disease, Essential Hypertension
The Northwest Coalition for Primary Care Practice Support
The purpose of this project is to build capacity for quality improvement (QI) in small primary care practices across Washington, Oregon and Idaho by improving risk factors for heart attacks such as blood pressure, cholesterol and…
- Conditions
- Cardiovascular Disease, Essential Hypertension, Nicotine Dependence, Hyperlipidemia
- Trial name
- H2N (NCT02839382)
- Testing
- Coaching, Educational Outreach, Site Visits
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Kaiser Permanente
Failure to Thrive
Trial of Home Visitation Among Infants With Failure To Thrive
1. Children in the home intervention group will have better growth (increase in weight and height) than children in the control group. 2.
- Trial name
- FTT (NCT00483691)
- Testing
- Home Visit
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Vaping, Lung Diseases
The e-BILD Study: Effects of E-cigarettes on Lung Health in Teenagers.
Electronic nicotine delivery systems (ENDS/e-cigarettes/vaping) are increasingly popular among teenagers around the world. The safety and potential adverse effects of ENDS in this population are largely unknown.
- Trial name
- e-BILD (NCT05105555)
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Infant,Premature, Bronchopulmonary Dysplasia
Enteral Zinc to Improve Growth in Infants at Risk for Bronchopulmonary Dysplasia
Multiple factors contribute to growth failure in infants with BPD, including poor nutrient stores, inadequate intake, increased losses, and increased needs.
- Conditions
- Infant,Premature, Bronchopulmonary Dysplasia, Growth Failure
- Trial name
- NCT03532555
- Testing
- Zinc Acetate, No supplemental zinc
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Utah
Growth Failure, Neurodevelopmental Disorder
High Energy Formula Feeding in Infants With Congenital Heart Disease
High energy formula more positively affect growth in infants with congenital heart disease compared to standard formula
- Trial name
- NCT01850784
- Testing
- High energy formula, Standard formula
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr. Sami Ulus Children's Hospital
Failure to Thrive, Nutritional Deficiency
Nasogastric Tube Securement Comparison Study
This study evaluates the use of tape to secure nasogastric tubes compared to securement with a nasal bridle device.
- Conditions
- Failure to Thrive, Nutritional Deficiency, Constipation, Bowel Obstruction
- Trial name
- NTSNB (NCT03202576)
- Testing
- Nasal Bridle
- Volunteers
- 43 people
- Sponsor
- University of Colorado, Denver
Anxiety, Depression Disorders
ABC School Intervention Among Ugandan Adolescents
Schools can be pivotal in addressing mental health challenges, especially in low-income settings like Uganda. This pilot cluster-randomized trial examines the impact of a culturally sensitive Act-Belong-Commit (ACT) intervention…
- Trial name
- NCT06957925
- Testing
- educational
- Where
- 2 sites in Uganda
- Volunteers
- 2,598 people
- Sponsor
- KU Leuven
Growth Failure, Intestinal Infection
MAL-ED Metabolic: A Follow-Up of Chronic Disease at Puberty
The concept that the roots of cardiometabolic disease start in early life was established by Dr. David Barker, who documented relationships between low birthweight (as a marker for challenges during gestation) and later…
- Conditions
- Growth Failure, Intestinal Infection, Metabolic Syndrome, Glucose Intolerance
- Trial name
- NCT05121935
- Volunteers
- 254 people
- Sponsor
- University of Virginia
Stunting, Birth Weight
Aflatoxin Birth Cohort Study Nepal (AflaCohort)
The study focuses on the causal relationship between mycotoxin exposure (particularly aflatoxin B1), birth outcomes, and height for age among young children in Nepal.
- Conditions
- Stunting, Birth Weight, Birth Length, Height for Age
- Trial name
- AflaCohort (NCT03312049)
- Volunteers
- 1,675 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cystic Fibrosis, Failure to Thrive
Clinical Study With an Enteral Formula With Symbiotic and DHA for Malnourished Children
The purpose of this study is to determine whether a nutritional supplement is effective in the treatment of malnutrition in pediatric patients with failure to thrive or cystic fibrosis.
- Conditions
- Cystic Fibrosis, Failure to Thrive, Malnutrition
- Trial name
- VITJUNIOR (NCT02128984)
- Testing
- Symbiotic Formula with DHA and antioxidants, Standard Formula
- Where
- 8 sites in Peru, Spain
- Volunteers
- 109 people
- Sponsor
- Laboratorios Ordesa