Clinical trials: No Condition
Pulmonary Hypertension
Study on the Use of Inhaled NO (iNO)
This is a prospective, observational, multicenter study conducted during 1 year in adult and paediatric intensive care units equipped with the EZ-KINOX™ system.
- Trial name
- POSITIVE (NCT02821156)
- Where
- 14 sites in Belgium, France
- Volunteers
- 239 people
- Sponsor
- Air Liquide Santé International
Hernia, Inguinal, Inguinal Hernia, Direct
Study of Laparoscopic Inguinal Hernia Repair
Although mesh fixation has been associated to an increased incidence of nerve injury and involves increased operative costs, many surgeons feel that fixation is necessary to reduce the risk of hernia recurrence.
- Conditions
- Hernia, Inguinal, Inguinal Hernia, Direct, Inguinal Hernia, Indirect, Hernia, Femoral
- Trial name
- NCT02920307
- Testing
- TEP without fixation, TEP with fixation, TAPP without fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Medical Park Gaziantep Hospital
Arrhythmia
The Effect of Proton Pump Inhibition on Palpitations
Feeling of palpitations with no clear arrhythmia is frequently encountered in clinical practice. The majority of these patients have documented sinus rhythm even while having symptoms.
- Trial name
- NCT03273634
- Testing
- Lansoprazole Pill
- Where
- Jordan
- Volunteers
- 150 people
- Sponsor
- Jordan Collaborating Cardiology Group
Surgical Site Infections
Effect of Cefazolin and Normal Saline Irrigation on Surgical Site Infections (SSIs)
This study conducted to assess the effects of normal saline or cefazolin irrigation on the incidence of SSIs. Hypothesis: Normal saline or cefazolin irrigation decreases the incidence of SSIs.
- Trial name
- NCT01566734
- Testing
- Cefazolin irrigation, Normal Saline Irrigation
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Hormozgan University of Medical Sciences
STEMI
Predictors of In-hospital and Short-term Clinical Outcomes in STEMI Patients Undergoing Primary PCI
The study aims to assess the culprit-SYNTAX score and no-reflow PIANO scores as possible predictors of in-hospital and short-term outcomes among patients with STEMI undergoing primary PCI
- Trial name
- NCT06123793
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Assiut University
Invasive Candidiasis, Candidemia
Micafungin Versus Fluconazole in the Treatment of Invasive Candidiasis and Candidemia
To determine the efficacy and safety of micafungin (FK463) versus fluconazole (Diflucan) in treating patients with invasive candidiasis or candidaemia
- Trial name
- NCT00189709
- Testing
- Micafungin, fluconazole
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Astellas Pharma Inc
Healthy, no Evidence of Disease, Obesity
Study of a Smart Growth Community's Effect on Prevention of Obesity in Middle-, Moderately Low- and Low-Income Families
RATIONALE: Overweight and obesity have been associated with multiple types of disease, including cancer. Living in a smart growth community may encourage behaviors that would reduce the risk of obesity.
- Conditions
- Healthy, no Evidence of Disease, Obesity, Weight Changes
- Trial name
- NCT00986011
- Testing
- questionnaire administration, study of socioeconomic and demographic variables, survey administration
- Where
- United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Asthma
A Study of Mometasone Furoate Metered Dose Inhaler in Children With Persistent Asthma (P04223)
The primary objective of this study is to demonstrate the dose-related efficacy, by evaluating morning (AM) lung function at the end of the dosing interval (AM pre-dose percent predicted forced expiratory volume in one second…
- Trial name
- NCT01502371
- Testing
- Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 25 mcg, Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 50 mcg, Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg
- Volunteers
- 583 people
- Sponsor
- Organon and Co
MS (Multiple Sclerosis), Multiple Sclerosis (MS) - Relapsing-remitting
Comparison of Efficacy and Safety in Patients Switching From MabThera® to Rixathon® in Relapsing-Remitting Multiple Sclerosis
This observational study investigates if switching from MabThera® to Rixathon® is associated with changes in disease activity and/or safety in people with multiple sclerosis (MS).
- Conditions
- MS (Multiple Sclerosis), Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (Relapsing Remitting)
- Trial name
- NCT07235644
- Where
- Sweden
- Volunteers
- 184 people
- Sponsor
- Uppsala University
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Nonseasonal
Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)
The purpose of this study is to assess the efficacy and safety of MK-8237 (SCH 900237) in the treatment of House Dust Mite (HDM)-Induced Allergic Rhinitis/Rhinoconjunctivitis (AR/ARC) in children and adults.
- Trial name
- NCT01700192
- Testing
- MK-8237 tablets, Rescue Medication: Self-Injectable Epinephrine, Rescue Medication: Loratadine tablets
- Volunteers
- 1,482 people
- Sponsor
- ALK-Abelló A/S
Vasovagal Syncope, Postural Tachycardia Syndrome
Mechanisms of Vasovagal Syncope
Vasovagal Syncope (simple postural faint) is the most common cause of acute loss of consciousness. Postural tachycardia syndrome(POTS) is the most common chronic form of postural lightheadedness.
- Trial name
- NCT01791816
- Testing
- Phenylephrine, L-Ng-monomethyl Arginine (L-NMMA)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- New York Medical College
Autism Spectrum Disorder
Peer Interventions for Preschoolers With Autism
This proposal will evaluate a series of peer-mediated interventions (PMIs) for preschool children (3 to 6 years) with ASD and limited or no spoken language, using an innovative Sequential Multiple Assignment Randomized Trial…
- Trial name
- PIPA (NCT05799599)
- Testing
- Stay-Play-Talk Basic, Stay-Play-Talk Plus, Stay-Play-Talk Advanced
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- University of Kansas
CMV Viremia, CMV Disease
Expanded Access Protocol of ATA230 (Third-Party Donor-Derived CMV-CTLs) for the Treatment of CMV Viremia or Disease
This is an expanded access protocol designed to provide access of ATA230 to subjects with cytomegalovirus (CMV) viremia or disease, who are intolerant to, or failed, standard antiviral therapy and have no comparable treatment…
- Trial name
- NCT03010332
- Testing
- Cytomegalovirus-specific Cytotoxic T Lymphocytes (CMV-CTLs)
- Sponsor
- Atara Biotherapeutics
Japanese Encephalitis
Safety of Vero Cell - Derived Inactivated Japanese Encephalitis Vaccine (JECEVAX) in Children From 9-24 Months of Age
A study of the study vaccine (JECEVAX- VABIOTECH-Vietnam) and a licensed vaccine (JEVAX-VABIOTECH-Vietnam) is conducted in Vietnamese children, aged 9 to 24 months to assess the safety of the study vaccine compares to licenced…
- Trial name
- JECEVAX-2B (NCT03204227)
- Testing
- JEVAX, JECEVAX
- Where
- 4 sites in Vietnam
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National Institute of Hygiene and Epidemiology, Vietnam
Pulmonary Hypertension
Iloprost-Study: Comparison of Nitric Oxide to Iloprost (Ventavis) for Treatment of Pulmonary Hypertension in Children After Cardiopulmonary Bypass Surgery
Inhaled nitrous oxide (iNO) will be compared to aerosolized iloprost (ILO) in pediatric patients after cardiac surgery with pulmonary hypertension.
- Trial name
- NCT00235521
- Testing
- aerosolized iloprost
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Heidelberg University
Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester
Tidal Neonatal NO, Vitamins A and D, and Infant Lung Disease - The AD-ON Study
Children born prematurely are of greater risk of developing chronic lung disease (Bronchopulmonary Dysplasia). With an increase in the amount of premature children, we expect an increasing number of children with BPD.
- Conditions
- Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester, Bronchopulmonary Dysplasia
- Trial name
- NCT01722760
- Testing
- measurements
- Where
- 2 sites in Denmark
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Myocardial Infarction
Nitroprusside for Prevention of no-Reflow in Primary Angioplasty
In patients admitted with acute myocardial infarction, there is a total occlusion of a coronary artery. Even after emergency catheterization and angioplasty, in some patients, the resumed blood flow is suboptimal and impacts on…
- Trial name
- NCT00128791
- Testing
- Nitroprusside
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Soroka University Medical Center
Asthma
A Serious Asthma Outcome Study With Mometasone Furoate/Formoterol Versus Mometasone Furoate in Asthmatics 12 Years and Over (P06241)
The purpose of this study is to test the safety of DULERA. DULERA is a pressurized metered-dose inhaler (MDI) that contains two drugs combined, namely mometasone and formoterol in a single inhaler.
- Trial name
- SPIRO (NCT01471340)
- Testing
- Mometasone Furoate/Formoterol MDI 100/5 mcg, Mometasone Furoate/Formoterol MDI 200/5 mcg, Mometasone Furoate MDI 100 mcg
- Volunteers
- 11,744 people
- Sponsor
- Organon and Co
No Disease or Condition is Being Studied, Stress Psychological
Supporting Secondary School Student Wellbeing Through a Mobile App and Wearable Biofeedback
This study aims to investigate the effects of an app and wearable device on the wellbeing of secondary school students. The app will offer support for stress management, sleep improvement, and time management.
- Conditions
- No Disease or Condition is Being Studied, Stress Psychological, Overall Wellness
- Trial name
- EWSSS (NCT06294210)
- Testing
- Mobile app and wrist-worn monitor
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
HbS Disease, Hemoglobin S Disease
A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD
HSCT is currently the only curative option for SCD but less than 20% of SCD patients have a MD donor available. So far, all curative approaches beyond a MSD HSCT at young age are non-satisfactory.
- Conditions
- HbS Disease, Hemoglobin S Disease, Sickle Cell Anemia, Sickle Cell Disorders
- Trial name
- NCT04201210
- Testing
- TCRα/β+ and CD19+ depleted haploidentical stem cell transplantation, Matched sibling donor transplantation
- Where
- 9 sites in Austria, Germany
- Volunteers
- 212 people
- Sponsor
- University of Regensburg