Clinical trials: Non-invasive
Noninvasive Ventilation, Child, Only
Custom Non-invasive Ventilation Masks in Children
One significant challenge to non-invasive ventilation (NIV) use in children is finding masks to fit a wide range of growing shapes and sizes.
- Conditions
- Noninvasive Ventilation, Child, Only, Adherence, Patient
- Trial name
- NCT05336136
- Testing
- Custom mask, Current commercial mask
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Noninvasive Ventilation, Preterm Infants
The Effectiveness of Non-Invasive Ventilation Use in Preterm Infants.
Prospective observational study of SNIPPV use in preterm infants of less than 32weeks of gestation from January 2012 to December 2015.
- Trial name
- NCT02628821
- Testing
- Preterm Infants treated with non-invasive ventilation.
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Children Sedation
Comparison of Chlorpromazine or Pentobarbital Premedications for Pediatric Imaging Procedures
Sedation is often required for pediatric medical imaging procedures to ensure compliance and quality images. Recommendations exist regarding pediatric sedation, but there are currently no guidelines regarding the choice of the…
- Trial name
- PREIMAPED (NCT04350528)
- Testing
- Chlorpromazine or Pentobarbital
- Where
- France
- Volunteers
- 254 people
- Sponsor
- University Hospital, Brest
Bladder Cancer
Urine-based Detection of Non-muscle Invasive Bladder
Non-muscle invasive bladder cancer (NMIBC), which comprises approximately 75% of bladder tumors, has the highest recurrence rate of all cancers, with around 70% of the patients developing local recurrences, despite elaborated…
- Trial name
- SOLUSION (NCT03962933)
- Where
- Denmark
- Volunteers
- 196 people
- Sponsor
- Nessn Azawi
Non Invasive Ventilation, Spinal Muscular Atrophy
Exploratory Study of Respiratory Bacterial Infections or Superinfections and Colonizations in Patients With Spinal Muscular Atrophy Under NIV
SMA (Spinal Muscular Atrophy) is a rare neuromuscular disease characterized by motoneuron damage. Symptoms consist of respiratory involvement with numerous respiratory infections and eventually respiratory failure, for which NIV…
- Conditions
- Non Invasive Ventilation, Spinal Muscular Atrophy, Respiratory Bacterial Infection
- Trial name
- AVNIR (NCT05712330)
- Testing
- non invasive ventilation samples, patient samples, parent questionnaire
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Respiratory Distress Syndrome
n-CPAP Versus n-BiPAP and NIPPV for Postextubation in RDS in Preterms
non-invasive ventilation in preterms complaining from RDS a randomized, controlled trial to compare between capap, n-bipap and NIPPV
- Trial name
- NCT01770925
- Testing
- N-CPAP, n-BiPAP, NIPPV
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence
Sacral Neuromodulation in Children and Adolescents
The purpose of this study is to assess the efficacy of neuromodulation for treatment of chronic constipation and fecal incontinence in pediatric patients and to evaluate the differences between the invasive vs.
- Conditions
- Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence, Hirschsprung's Disease, Anorectal Malformations
- Trial name
- NCT04713085
- Testing
- Invasive Sacral Neuromodulation, Non-invasive Sacral Neuromodulation
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Vegetative State, Minimally Conscious State
Prefontal tDCS in Patients With Disorders of Consciousness: Neurophysiological and Behavioural Outcomes
Non-invasive brain stimulations techniques have recently shown promising results in patients with disorders. Notably, transcranial direct current stimulation (tDCS) applied over the left dorsolateral prefrontal cortex has proved…
- Conditions
- Vegetative State, Minimally Conscious State, Disorder of Consciousness
- Trial name
- NCT03823508
- Testing
- anodal tDCS
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University of Liege
Hydrocephalus in Infants
Non-Invasive Pressure Monitor for Neonates & Infants at Risk of Developing Hydrocephalus
The goal of this clinical trial is to test a modified smart soft contact lens in neonates and infants at risk of developing hydrocephalus.
- Trial name
- NCT06310213
- Testing
- Non-Invasive Pressure Monitor
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Respiratory Distress Syndrome, Newborn, Infant, Premature
Neural Control of Non-invasive Ventilation in the Preterm
The present study will use a new type of respirator in premature babies who need help with their breathing. This new respirator uses signals from the baby's diaphragm - the most important breathing muscle - to control the timing…
- Trial name
- NCT00368485
- Testing
- Neurally Controlled Mechanical Ventilation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Fabry Disease
Podocyturia - Predictor of Renal Dysfunction in Fabry Nephropathy
In patients with Fabry disease, this research study explores the presence of podocytes in their urine as a potential non-invasive biomarker for baseline kidney disease; and explores changes in the quantity of podocytes in their…
- Trial name
- NCT02994303
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Washington
Central Venous Pressure
Non-invasive Central Venous Pressure Estimation in Pediatric Patients
Central Venous Pressure (CVP) is a standard parameter for hemodynamic monitoring and is currently measured through the insertion of a catheter.
- Trial name
- CPMX-CVP-Ped (NCT06885073)
- Testing
- CPMX2
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Compremium AG
Unstable Blood Pressure, Hypotension
Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS
The goal of this study is to evaluate if a novel near-infrared spectroscopy (NIRS) device can accurately estimate blood pressure in newborns at risk for unstable blood pressure.
- Trial name
- NCT06994494
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
COVID-19
Transcranial Non-invasive Electrical Stimulation of the Vagus Nerve in Hospitalized Moderate-to-severe COVID-19 Patients
Subtle Pulse Electro-biological Recovery Apparatus (SPERA) is an innovative device which delivers digital subliminal pulse stimulation trans cranially to auricular branches of the central nervous system and modulates the…
- Trial name
- NCT06767241
- Testing
- Non-invasive auricular vagus nerve stimulation, Standard Medical Therapy
- Where
- Romania
- Volunteers
- 83 people
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
Hypertension, Hypotension
Accuracy of Non-Invasive Blood Pressure Measurement in Adults
The purpose of this study is to compare the accuracy of the Sotera ViSi, an investigational device, to auscultation (measurement with a cuff) in determining systolic and diastolic blood pressure (BP) in adult subjects.
- Trial name
- NIBP (NCT01183741)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sotera Wireless, Inc.
Mechanical Ventilation Complication
Non Invasive Mechanical Ventilation VERSUS Oxygen MASK
Conventional mechanical ventilation is a core feature of intensive care. Weaning and removal of endotracheal tube are crucial processes, which often account for a considerable part of Conventional mechanical ventilation total…
- Trial name
- NCT03259854
- Testing
- non invasive mechanical ventilation in pediatrics, oxygen mask
- Volunteers
- 104 people
- Sponsor
- Assiut University
Tetanus
TETANUS Antibody Detection in Saliva Study
This study aims to design, develop and optimise a non-invasive, saliva sample-based point-of-care lateral flow test for use in low and middle income settings that can return a qualitative result on whether an individual has or…
- Trial name
- TETANUS (NCT07446166)
- Testing
- Point of care, saliva-based lateral flow test, Blood based immunoassay
- Where
- Rwanda
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Urine Specimen Collection
The Effect of Non-invasive Bladder Stimulation Technique on Collecting Urine Specimen in Infants Under One Year Old
Urinary tract infection (UTI) is common in early childhood. The American Academy of Pediatrics accepts suprapubic aspiration and bladder catheterization as the gold standard for the diagnosis of UTI.
- Trial name
- NCT05394454
- Testing
- Bladder stimulation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University - Cerrahpasa
Angina Pectoris, Microvascular Angina
Angina in Non Coronary Artery Disease
Many patients undergoing coronary angiography are found to have no significant coronary artery disease (CAD) despite angina equivalent symptoms and/or electrocardiographic abnormalities suggestive of myocardial ischemia.
- Conditions
- Angina Pectoris, Microvascular Angina, Angina Pectoris, Variant
- Trial name
- HeartQuest (NCT01318629)
- Where
- Switzerland
- Volunteers
- 718 people
- Sponsor
- Luzerner Kantonsspital
Bladder Cancer
Investigating Bladder Chemotherapy Instead of Surgery for Low Risk Bladder Cancer
Patients diagnosed with low risk non-muscle invasive bladder cancer (NMIBC) are at risk of frequent low grade recurrence, which usually necessitates surgical intervention under general anaesthetic.
- Trial name
- CALIBER (NCT02070120)
- Testing
- Mitomycin C, Surgical Management
- Where
- 38 sites in United Kingdom
- Volunteers
- 82 people
- Sponsor
- Institute of Cancer Research, United Kingdom