Clinical trials: Non-responders
Wet AMD
Genetics Study of Wet Age-Related Macular Degeneration (AMD) Non-Responders to Vascular Endothelial Growth Factor (VEGF) Therapy
To obtain a genotypic analysis of patients with chronic exudative age-related macular degeneration noted to have subretinal or intraretinal edema despite continuous monthly Anti-VEGF therapy.
- Trial name
- NCT01310686
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- West Coast Retina Medical Group, Inc.
Metabolism Disorder, Insulin Sensitivity
Supervised Exercise-training in Children With Insulin Resistance or Healthy Metabolic Profile
Despite exercise training decrease blood fasting glycemia in 'average' terms, there is a wide interindividual variability after exercise training explored mainly in adults but not in children.
- Conditions
- Metabolism Disorder, Insulin Sensitivity, Obesity, Pediatric
- Trial name
- NCT03003754
- Testing
- High Intensity Training (HIT) + Resistance Training (RT), Control group
- Where
- Colombia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
Major Depressive Disorder
Creatine Treatment for Female Adolescents With Depression Who Are Non-Responders to Fluoxetine or Escitalopram
The purpose of this study is to see if creatine, which is a naturally occurring chemical in the body, is effective for treating Major Depressive Disorder (MDD) in female teenagers.
- Trial name
- NCT00851006
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Utah
Athletic Performance, Aerobic Capacity
Individualized Training to Improve Aerobic Capacity and 2,000 m Rowing Performance in Youth Rowers
The goal of this randomized clinical trial is to learn whether an individualized rowing training program based on ventilatory thresholds can improve aerobic capacity and 2,000 m rowing performance in youth rowers from Valdivia…
- Conditions
- Athletic Performance, Aerobic Capacity, Rowing Performance
- Trial name
- NCT07602244
- Testing
- Individualized Rowing Training, Usual Rowing Training
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Osteoporosis
The Effectiveness of Eldecalcitol in the Bisphosphonate Non-respondered-patients With Osteoporosis
In the patients with osteoporosis, bisphosphonates (BPs) are a golden standard treatment. However, the bone turnover markers or the bone mineral density (BMD) are not improved in some osteoporotic patients even though they have…
- Trial name
- NCT02306187
- Testing
- Edirol
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shinshu University
Adolescents, Physical Activity
School-based HIIT and Dose-Response Effects
There are experimental evidences of the importance of high intensity exercises in health outcomes improvement. However, there are limited knowledge about possibility to affect health outcomes in adolescents through exercises…
- Conditions
- Adolescents, Physical Activity, Adipose Tissue, Blood Pressure
- Trial name
- PEER-HEART (NCT06431230)
- Testing
- standard high-intensity interval training, plyometric high-intensity interval training
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences