Clinical trials: Normal Skin
Breast Cancer
High Dose Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Therapy in Treating Women With Metastatic or Recurrent Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Trial name
- NCT00003032
- Testing
- filgrastim, cisplatin, cyclophosphamide
- Where
- 25 sites in Canada
- Volunteers
- 224 people
- Sponsor
- NCIC Clinical Trials Group
HIV, Lipodystrophy
The Cleveland Cardiometabolic Cohort
In this observational study, the investigators will examine the changes in body composition in HIV-infected subjects before and after initiation of HIV treatment, and look at the correlations with changes in cardiometabolic…
- Trial name
- NCT03059121
- Testing
- Dual-energy X-ray absorptiometry
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University Hospitals Cleveland Medical Center
Acne Vulgaris
A Phase 3, Vehicle-controlled Efficacy and Safety Study of IDP-123 Lotion in the Treatment of Acne Vulgaris (301)
This is a multicenter, randomized, double-blind, vehicle-controlled, 12-week study designed to assess the safety, efficacy, and tolerability of IDP-123 Lotion in comparison with IDP-123 Vehicle Lotion.
- Trial name
- NCT03168321
- Testing
- IDP-123 Lotion, IDP-123 Vehicle Lotion
- Where
- 45 sites in United States, Canada
- Volunteers
- 813 people
- Sponsor
- Bausch Health Americas, Inc.
Normal Children
Rehacom or Wechsler Assessment Methodology in Cognitive Abilities of Normal Children: Correlation Study
The purpose of this study is to investigate the relationship between a computerized cognitive assessment tool (Rehacom) and a traditional intelligence scale (Wechsler Intelligence Scale for Children) in assessing cognitive…
- Trial name
- NCT07819006
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Lichen Planus
Treatment Modalities of Oral Lichen Planus
Background: Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous autoimmune disease mainly affecting stratum basal of the epithelium. It is very painful and hamper the daily routine of patients e.g.
- Trial name
- OLP (NCT03237533)
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- University of Faisalabad
Breast Diseases
Effect of Peppermint Water on Breast Crack
To evaluate the effectiveness of a topical preparation of peppermint water in comparison with that of expressed breast milk for the prevention of nipple cracks in primiparous breastfeeding women.
- Trial name
- NCT00456404
- Testing
- peppermint water
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Tabriz University
Darier Disease, Hailey-Hailey Disease
National Registry for Ichthyosis and Related Disorders
The ichthyoses are a family of genetic skin diseases characterized by dry, thickened, scaling skin. Dermatologists estimate that there are over twenty varieties of ichthyosis, with a wide range of severity and associated…
- Conditions
- Darier Disease, Hailey-Hailey Disease, Hyperkeratosis, Epidermolytic, Ichthyosis
- Trial name
- NCT00074685
- Where
- United States
- Volunteers
- 610 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Vitiligo
Comparative Study of Surgical Treatment of Vitiligo
A comparative study for the surgical treatment of vitiligo in which the same patient will receive in acromic and symmetric lesions of vitiligo dermabrasion with micro needling and on the other side dermabrasion with micro…
- Trial name
- NCT03497208
- Testing
- Microneedling, Cell suspension, Phototherapy
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Retained Placenta
Intraumbilical Misoprostol in Retained Placenta
Administration of intraumbilical misoprostol to women with retained placenta despite active management of third stage of labour reduces the need for manual removal of placenta and the amount of blood loss vaginally.
- Trial name
- NCT01840813
- Testing
- Misoprostol, Normal saline
- Where
- Iraq
- Volunteers
- 46 people
- Sponsor
- Hawler Medical University
Breast Cancer
Evaluation of Prognostic Monitoring for Women Who Have Completed Standard Treatment for Breast Cancer
The relationship between immune inflammation-related protein complexes in blood and recurrence or metastasis of breast cancer will be studied.
- Trial name
- NCT04145960
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Osteoarthritis, Knee, Arthritis, Rheumatoid
Gamma Vacuum Foil (GVF) Versus Cross-linked Polyethylene in Total Knee Arthroplasty Study
The purpose of this study is to evaluate long-term clinical and radiographic data between geometrically identical GVF and cross-linked polyethylene-bearing inserts in total knee arthroplasty.
- Trial name
- NCT00289133
- Testing
- total knee arthroplasty
- Where
- 9 sites in United States
- Volunteers
- 938 people
- Sponsor
- DePuy Orthopaedics
Breast Cancer
Influence of Fibrin Glue on Seroma Formation After Modified Radical Mastectomy
This study was carried out from January 2005 to December 2007 at Mansoura university hospital. Fifty patients who had breast cancer were included in the study, MRM was done for all patients.
- Trial name
- MRM (NCT00909649)
- Testing
- fibrin glue in breast surgery
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Acne
Combination Treatment for Moderate to Severe Acne
To determine if a combination of three currently approved acne products are safe and effective for the treatment of moderate to severe acne
- Trial name
- NCT01206348
- Testing
- Minocycline, Clindamycin, Tretinoin, Benzoyl Peroxide
- Where
- 10 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Medicis Global Service Corporation
Atrial Fibrillation
The Effect of Low Intensity Exercise on Quality of Life and Hemodynamics in Patients With Permanent Atrial Fibrillation
The purpose of this study is to 1) assess the effect of routine exercise on the quality of life of patients with permanent atrial fibrillation, and 2) assess the effect of exercise on cardio-hemodynamics in patients with atrial…
- Trial name
- NCT00680290
- Testing
- Exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Graft Versus Host Disease, Systemic Scleroderma
Imatinib and Rituximab in Treating Cutaneous Sclerosis in Patients With Chronic Graft-Versus-Host Disease
This randomized phase II trial is evaluating how well imatinib mesylate works compared to rituximab in treating cutaneous sclerosis in patients with chronic graft- versus-host disease (GVHD).
- Trial name
- NCT01309997
- Testing
- imatinib mesylate, rituximab
- Where
- 10 sites in United States
- Volunteers
- 72 people
- Sponsor
- Lee, Stephanie
Skin Diseases, Bacterial
Avelox in Complicated Skin and Skin Structure Infections
This international, prospective, non-interventional, non-controlled observational study obtains data on efficacy, safety and tolerability of Avelox treatment under daily-life treatment conditions.
- Trial name
- ARTOS (NCT00997997)
- Testing
- Moxifloxacin (Avelox, BAY12-8039)
- Where
- 12 sites in Austria, Bulgaria and 10 more
- Volunteers
- 6,127 people
- Sponsor
- Bayer
Rheumatic Diseases, Lupus Erythematosus, Systemic
Pain Phenotyping of Rheumatic Diseases - An Observational Study
Background: Rheumatic diseases can affect the joints, ligaments, tendons, bones, muscles, and skin. They can also cause inflammation, damage body tissues, and change nerve signals in the brain.
- Conditions
- Rheumatic Diseases, Lupus Erythematosus, Systemic, Lupus Vasculitis, Central Nervous System, Arthritis
- Trial name
- NCT07829497
- Testing
- Bedside quantitative sensory testing
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Systemic Lupus Erythematosus
Belimumab (BENLYSTA®) Pregnancy Registry
This global Belimumab Pregnancy Registry will collect prospective data on pregnancies and pregnancy outcomes on a voluntary basis in women with systemic lupus erythematosus (SLE) who have received commercially supplied belimumab…
- Trial name
- NCT01532310
- Testing
- belimumab
- Where
- 15 sites in United States, Austria and 10 more
- Volunteers
- 77 people
- Sponsor
- GlaxoSmithKline
TNF-receptor Associated Periodic Syndromes (TRAPS)
Efficacy and Safety Study of ACZ885 in Patients With Active Recurrent or Chronic TNF-receptor Associated Periodic Syndrome (TRAPS).
This trial will assess the safety and efficacy of ACZ885 in patients with active recurrent or chronic TNF-receptor associated periodic syndrome (TRAPS).
- Trial name
- NCT01242813
- Testing
- ACZ885
- Where
- 6 sites in Ireland, Italy and 1 more
- Volunteers
- 20 people
- Sponsor
- Novartis Pharmaceuticals
Acne Vulgaris
A Study to Compare the Efficacy, Safety and Pharmacokinetics of Trifarotene 50 mcg/g Cream in Chinese Subjects With Acne Vulgaris
The primary objective is to assess the efficacy of trifarotene 50 microgram per gram (mcg/g) cream versus vehicle cream when applied once daily (QD) for 12 weeks in Chinese participants with moderate facial and truncal acne…
- Trial name
- AKLIEF (NCT07186413)
- Testing
- Trifarotene, Vehicle Cream
- Where
- China
- Volunteers
- 561 people
- Sponsor
- Galderma R&D
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