Clinical trials: Normal Weight
Psoriasis, Atopic Dermatitis
Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index
The object of this research study is to examine these associations in children as very little is known about psoriasis and cardiovascular risk factors in the pediatric population.
- Trial name
- NCT00879944
- Testing
- Blood pressure, Height, Weight
- Where
- 14 sites in United States, Canada and 4 more
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Paracetamol, Cefazolin
Paracetamol and Cefazolin Pharmacokinetics in Normal Weight and Overweight Children
Pharmacokinetic evaluations will be conducted to characterize the cefazolin plasma concentration-time profile, cefazolin penetration into subcutaneous adipose tissue, and paracetamol metabolization as assessed through blood…
- Trial name
- TISSUE (NCT07585487)
- Testing
- Cefazolin, Paracetamol (drug)
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- University Hospital, Ghent
Psoriasis
Post-Marketing Surveillance Study of OTEZLA
To evaluate the safety and efficacy of OTEZLA in actual clinical settings of use in patients with Psoriasis vulgaris that is with an inadequate response to topical therapies and Psoriasis arthropathica 1.
- Trial name
- NCT03284879
- Where
- Japan
- Volunteers
- 1,086 people
- Sponsor
- Amgen
Obesity, Obesity, Abdominal
Environmental Temperature and Human White Adipose Tissue
Obesity is characterized by excessive white adipose tissue (WAT) that increases risk for disease. About 700 million adults are obese worldwide, designating the need of reducing excessive WAT in humans and subsequently the risk…
- Conditions
- Obesity, Obesity, Abdominal, Obese
- Trial name
- NCT04037371
- Testing
- Cold exposure
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Petros Dinas
Ewing Sarcoma, Osteosarcoma
Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults
The purpose of the study was to investigate whether functional MRI imaging (diffusion weighted imaging) is useful for monitoring the therapeutic response of bone sarcomas in children and young adults.
- Trial name
- FUBEO (NCT01780779)
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Overweight, Obesity
Role of Dietary Protein on Satiety, Food Intake and Thermic Effect of Food
Objectives: To determine the effect of protein content of familiar breakfast meals on subjective appetite, food intake (FI), glycemic response and Thermic Effect of Food (TEF) in normal weight (NW) and overweight (OW)/obese (OB)…
- Trial name
- NCT02200796
- Testing
- Control Meal, Low Protein Meal, Moderate Protein Meal
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Obesity
Sugars-sweetened Commercial Beverages on Short-term Food Intake
The purpose of this experiment was to describe the effect of consuming 350 ml of 1% chocolate milk 60 minutes before a pizza meal on subjective appetite and short-term food intake when compared to cola, a fruit drink and a water…
- Trial name
- NCT01717703
- Testing
- Water, Fruit drink, Cola
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Pediatric Obesity, Pediatric Dentistry
Oral Health in Children and Adolescents With Obesity and Normal Weight
We aimed to compare the oral health status (dmft/DMFT index, IDCAS-II, BEWE, plaque index, gingival index, probing depth) between normal-weight (NW) and obese (OW) children/adolescents.
- Trial name
- NCT06283602
- Testing
- oral health status
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Breast Neoplasms
Effects of Aerobic Exercise Versus Weight Training in Breast Cancer Survivors During Chemotherapy
The purpose of this study is to compare the effects of two different types of exercise, aerobic exercise training (AET) and resistance exercise training (RET), on quality of life (QoL) in early stage breast cancer survivors…
- Trial name
- NCT00115713
- Testing
- Aerobic Exercise Training, Resistance Exercise Training
- Where
- 3 sites in Canada
- Volunteers
- 240 people
- Sponsor
- University of Alberta
Obesity
Effects of Exercise Intensity in Obese Children and Adolescents
The prevalence of paediatric obesity has increased over the last two decades and with it, an increased diagnosis of lifestyle-related diseases in children and adolescents.
- Trial name
- NCT01991106
- Testing
- High intensity interval training, Moderate intensity continuous training, Nutritional advice
- Where
- 2 sites in Australia, Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Pediatric Obesity, Insulin Resistance
Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance
The primary objective of this randomized, parallel group, double-blind, placebo-controlled study is to determine whether treatment with metformin enhances insulin sensitivity in a group of ethnically diverse obese…
- Conditions
- Pediatric Obesity, Insulin Resistance, Hyperinsulinemia
- Trial name
- NCT00667498
- Testing
- Metformin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Sarcoma, Bone, Sarcoma, Soft Tissue
Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas
Children with sarcomas are routinely assessed with a variety of imaging techniques that involve the use of ionizing radiation. These include computed tomography (CT), nuclear bone scan, and positron emission tomography-CT…
- Conditions
- Sarcoma, Bone, Sarcoma, Soft Tissue, Osteosarcoma, Sarcoma, Ewing
- Trial name
- NCT02415816
- Testing
- Diffusion Weighted Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- St. Jude Children's Research Hospital
Glioma, Neoplasms
Study on Neuroepithelial Tumor Grading and Pseudoprogression After Glioma Therapy Using Advanced Functional MRI Techniques
Contrast-enhanced MRI is the most common way for evaluating neuroepithelial tumor grading and monitoring for tumor recurrence,but the ability to predict tumor behavior remains very limited.In this study, the investigators will…
- Trial name
- NCT02622620
- Volunteers
- 86 people
- Sponsor
- Tang-Du Hospital
Pediatric Obesity
Factors Associated With Changes in Weight-status in Danish School Children With Obesity
Childhood obesity is increasing worldwide and causes a major health concern. Only limited insight exists into the natural history of childhood obesity at children already classified as obese.
- Trial name
- NCT06077266
- Testing
- Change of weight class to normal weight
- Where
- Denmark
- Volunteers
- 467 people
- Sponsor
- University of Aarhus
Obesity, Weight Loss
Hormonal Regulation of Body Weight Maintenance
The investigators here propose to perform a collaborative clinical research effort including a randomized controlled trial investigating the mechanisms of weight maintenance and their relation to a lifestyle intervention in…
- Conditions
- Obesity, Weight Loss, Weight Gain, Hormone Disturbance
- Trial name
- NCT00850629
- Testing
- multimodal lifestyle intervention
- Where
- Germany
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Non-exercise Activity Thermogenesis
Non-Exercise Activity Thermogenesis (NEAT) in Children
Non-exercise activity thermogenesis (NEAT) is the energy expended engaging in daily activities such as maintenance of posture, fidgeting, and other activities not specifically designated as "exercise." A growing body of evidence…
- Trial name
- NCT00315172
- Testing
- Non-Exercise Activity Thermogenesis (NEAT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Scabies
Ivermectin Safety in Small Children
This trial will evaluate the safety, pharmacokinetics, and efficacy of ivermectin in scabies infected children weighing 5 to less than 15kg.
- Trial name
- ISSC (NCT04332068)
- Testing
- Oral ivermectin, Permethrin Cream
- Where
- 3 sites in Brazil, Kenya and 1 more
- Volunteers
- 240 people
- Sponsor
- University of Oxford
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Neonatal Sepsis, Low Birth Weight
Safety of Skin Cleansing With Chlorhexidine in Preterm Low Birth Weight Infants
The purpose of this study is to examine if single skin cleansing with 0.25% chlorhexidine affects skin condition, temperature, and bacterial colonization in stable preterm (28-36 weeks gestational age) low birth weight (1001-2000…
- Trial name
- NCT00947518
- Testing
- Chlorhexidine, Normal saline
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
Bone Health, Cognitive Health
Skeletal and Cognitive Effects of Nutrition From Eggs
This project is the first egg feeding randomized controlled trial (RCT) in children. The goal of this RCT is to determine if eating formulated whole egg products for 9 months improves bone health and cognitive function in…
- Trial name
- SCENE (NCT03739424)
- Testing
- Whole egg powder, Whole milk powder, Gelatin food product
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Georgia