Clinical trials: Obesity Associated Disorder
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Psychotic Disorders
Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics
This study will test the effectiveness of two different treatments for children and adolescents who have gained weight on their antipsychotic medications.
- Trial name
- IMPACT (NCT00806234)
- Testing
- Aripiprazole or Perphenazine, Metformin, Olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole, asenapine, iloperidone, lurasidone, paliperidone, or olanzapine/fluoxetine
- Where
- 4 sites in United States
- Volunteers
- 127 people
- Sponsor
- Johns Hopkins University
Malnutrition in Children, Undernutrition
Nutrition Intervention Among Ethnic Minority Children Aged 5-16 Years in Tra Vinh Province, Vietnam
The goal of this study is to evaluate the effectiveness of a nutrition health education intervention among ethnic minority children aged 5-16 years in Tra Vinh Province, Vietnam.
- Conditions
- Malnutrition in Children, Undernutrition, Overweight, Obesity
- Trial name
- NCT07583667
- Testing
- Nutrition Health Education
- Where
- Vietnam
- Volunteers
- 811 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Metabolic Dysfunction-Associated Steatotic Liver Disease, Pediatric Obesity
Non-Invasive Diagnostic Panel for MASLD in Children With Obesity
This prospective, single-center, two-group observational study evaluates a non-invasive multi-parameter diagnostic panel for metabolic dysfunction-associated steatotic liver disease (MASLD) in children with obesity.
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Pediatric Obesity, Insulin Resistance Syndrome
- Trial name
- PedMASLD-Pilot (NCT07731360)
- Testing
- Non-Invasive Multi-Parameter Diagnostic Panel
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Kayseri City Hospital
Breast Cancer, Health, Subjective
Role of Pro-Resolving Lipid Mediators in Obesity-Associated Diseases
The main objective of this project is to determine the possible association between the levels of certain bioactive lipids, which the body produces from dietary fatty acids, and tumor characteristics in breast cancer patients, as…
- Conditions
- Breast Cancer, Health, Subjective, Obesity
- Trial name
- RESOLBE (NCT07447440)
- Testing
- Observational study (baseline), Observational study (baseline and 1 year)
- Where
- 2 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Adult Women, Overweight
Effects of Flaxseed Flour in Appetite Sensations, Lipid Profile and Pressure Levels Among Overweighed and Obese Women
Inclusion of foods rich in fiber, such as flaxseed, is a nutritional strategy for treating obesity. The hypothesis of this study is to compare the effects of three types of flaxseed flour - whole brown flaxseed flour, brown…
- Conditions
- Adult Women, Overweight, Obese
- Trial name
- NCT01549626
- Testing
- Defatted flaxseed flour, Golden flaxseed flour, Whole brown flaxseed flour
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Pediatric Obesity
Factors Associated With Changes in Weight-status in Danish School Children With Obesity
Childhood obesity is increasing worldwide and causes a major health concern. Only limited insight exists into the natural history of childhood obesity at children already classified as obese.
- Trial name
- NCT06077266
- Testing
- Change of weight class to normal weight
- Where
- Denmark
- Volunteers
- 467 people
- Sponsor
- University of Aarhus
Childhood Obesity
Whole-exome Sequencing in Childhood Obesity
Obesity is a complex multifactorial disease where genetics play an important role in predisposing children to early onset obesity.
- Trial name
- NCT02418377
- Where
- 2 sites in Singapore
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Bariatric Surgery Candidate, Obesity, Morbid
Adolescents Bariatric Surgery Cohort Survey
Obesity affects 3%-4% of the pediatric population and leads to cardiac mortality during adult life. Bariatric surgery is the best treatment for weight loss and preventing obesity associated comorbidities in adults, but its…
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Obesity, Adolescent
- Trial name
- BariAdo (NCT04766801)
- Testing
- Laparoscopic adjustable gastric banding
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Overweight/obesity, Metabolic Associated Fatty Liver Disease
Effect of Low Valine Diet on Body Weight and Metabolic Parameters
This study aimed to explore the effects of ordinary meal replacements and low-valine meal replacements on the weight and risk of related metabolic diseases in overweight/obese patients through a randomized double-blind controlled…
- Conditions
- Overweight/obesity, Metabolic Associated Fatty Liver Disease, Metabolic Diseases
- Trial name
- NCT06883578
- Testing
- Short-term continuous normal meal replacement, Short-term continuous low-valine meal replacements, Long-term intermittent normal meal replacement
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Shanghai Zhongshan Hospital
Obesity Associated With Defects in Leptin-melanocortin Pathway
Long Term Extension Trial of Setmelanotide
This was a long-term extension trial to study the safety and tolerability of continued setmelanotide treatment in participants who had completed a previous clinical trial on treatment with setmelanotide for obesity associated…
- Trial name
- NCT03651765
- Testing
- Setmelanotide
- Where
- 27 sites in United States, Canada and 6 more
- Volunteers
- 205 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Hepatic Disorders, Intestinal Failure-associated Liver Disease
VALidation of Imaging-based Liver Biomarkers in PEDiatric Patients
The goal of this observational (diagnostic validation) study is to validate imaging-based biomarkers for assessing liver involvement in pediatric patients with established or suspected liver disease.
- Conditions
- Hepatic Disorders, Intestinal Failure-associated Liver Disease, Cystic Fibrosis Liver Disease, MAFLD
- Trial name
- VALiBi-PED (NCT07202910)
- Where
- Sweden
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital