Clinical trials: Observatory
Puberty, Precocious
First Observatory of Precocious Puberty.
The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe.
- Trial name
- PAPPEL (NCT06263868)
- Where
- 23 sites in France
- Volunteers
- 3,360 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Bilateral Upper Limb Amputation, Transverse Short Amputation of the Hand
Bilateral Upper Limb Amputation Observatory
In France, there is currently no data to directly estimate the number of bilateral upper limb amputations, their characteristics and therapeutic care.
- Conditions
- Bilateral Upper Limb Amputation, Transverse Short Amputation of the Hand, Arm Amputation
- Trial name
- ARMOBS (NCT02835378)
- Testing
- No intervention
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Helicobacter Pylori Infection
French Pediatric Helicobacter Pylori Observatory
Helicobacter pylori is a major human pathogen associated with significant morbidity. The treatment oriented by the antibiogram or PCR (Polymerase Chain Reaction) should be privileged in children.
- Trial name
- GFHPP (NCT03541876)
- Testing
- Collection of data
- Where
- France
- Volunteers
- 1,201 people
- Sponsor
- Lille Catholic University
Covid-19
Use of PCR-Sars-CoV-2 in Children
The VIGIL study was set up at the beginning of the pandemic, in the spring of 2020, at a time when diagnostic testing for SARS-CoV-2 had to be performed according to specific clinical criteria (even if no clinical picture…
- Trial name
- VIGIL (NCT04412317)
- Where
- 2 sites in France
- Volunteers
- 12,000 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Cardiogenic Shock
French Observatory on the Management of Cardiogenic Shock 2
The aim of this observational study is to describe the baseline characteristics, management strategies, and early outcomes (during hospitalisation and at 30 days) of patients admitted to intensive care with cardiogenic shock…
- Trial name
- FRENSHOCK 2 (NCT07868757)
- Where
- 2 sites in France
- Volunteers
- 1,000 people
- Sponsor
- French Cardiology Society
Mycoplasma Infections, Hospitalized Children
National Observatory of Mycoplasma Infections in Children Under 18 Ages in France
This study was set up because of an unusual increase in the number of cases of mycoplasma infections in France between June and November 2023.
- Trial name
- ORIGAMI (NCT06260371)
- Where
- France
- Volunteers
- 1,145 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Severe Asthma
Severe Asthma Network Italy
The goal of this registry is collecting data of severe asthma patients, recruited by specialized centers, in a real life setting, homogeneously placed on a database management system to follow them over the time.
- Trial name
- SANI (NCT06625216)
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- Società Italiana di Allergologia, Asma e Immunologia Clinica
Leukemia, Myeloid, Acute
ObServatory Children Acute RElated Therapy Leukemia
Acute Myeloid Leukemias (AML) of the child are a rare disease and its prognosis varies according to the subgroup. Secondary AMLs remain a subgroup of poor prognosis, whose cytogenetic and molecular characteristics and prognostic…
- Trial name
- OSCARE (NCT04450784)
- Testing
- collection of the clinical and biological characteristics of secondary AMLs in children
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Food Protein Induced Enterocolitis Syndrome (FPIES)
A Multicentre French Prospective Study of Children With Food Protein Induced Enterocolitis Syndrome in Its Acute Form
Food protein induced enterocolitis syndrome (FPIES), is a non-IgE mediated food allergy (FA) which seems to expand, and occurring in infancy. This disease is usually unknown by clinicians.
- Trial name
- SEIPA-FPIES (NCT05528900)
- Testing
- allergy test
- Where
- 19 sites in France
- Volunteers
- 600 people
- Sponsor
- Fondation Lenval
Food Allergy
Observatory on Cow's Milk Protein Allergy
The purpose of this study is to describe the symptoms and their evolution up to the age of 5 years in a population of newly diagnosed infants with a suspected or confirmed allergy to cow proteins, for whom the doctor prescribed…
- Trial name
- OLAF (NCT06085118)
- Testing
- Pepticate® Syneo®
- Where
- 2 sites in France
- Volunteers
- 3,000 people
- Sponsor
- Nutricia Nutrition Clinique
Cancer
Population-based Cancer Observatory
Cancer is the leading cause of death in Western countries. In France cancer control plans (National screening programmes) and recommendations for the management of cancer patients (multidisciplinary team meetings), have been…
- Trial name
- cancer observ (NCT03687151)
- Testing
- non intervention / observationnal
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nice
Haemophilia B
Observatory of Patients With Haemophilia B Treated by IdElvion®
OrPHEe is a non-interventional, prospective and national study which aim is to record real life data in haemophilia B French patients treated with Idelvion® to confirm the efficacy and safety of this product established in…
- Trial name
- OrPHEe (NCT05086575)
- Where
- 28 sites in France
- Volunteers
- 222 people
- Sponsor
- CSL Behring
Glycogen Storage Disease Type III
French Observatory for Patients with Type 3 Glycogenosis
Glycogen storage disease type III (GSD-III) or Cori/Forbes disease, is caused by autosomal recessive mutations in the AGL gene, which codes for the glycogen debranching enzyme (GDE) involved in the release of glucose-1P from…
- Trial name
- NCT06616545
- Where
- 3 sites in France
- Volunteers
- 150 people
- Sponsor
- Institut de Myologie, France
Mental Disorders
French Observatory of ElectroConvulsive Therapy (ECT)
Since the 30s, ECT has been a psychiatric treatment mainly used for drug-resistant depressive illnesses. Clinical studies have shown its therapeutic efficiency compared to standard treatments also in other psychiatric illnesses.
- Trial name
- NCT04477434
- Where
- 30 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Centre Hospitalier Henri Laborit
Para-prosthetic Heart
Para-Prosthetic Valve Leak Closure Observatory - PVLC2
Para-prosthetic heart valve leakage is an evolving complication after surgical or percutaneous heart valve replacement. These leaks can lead to heart failure and/or life-threatening hemolysis.
- Trial name
- FFPP2 (NCT07049991)
- Testing
- surgical or percutaneous heart valve replacement.
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Bronchiolitis
National Observatory of Children Hospitalized With Bronchiolitis
OVNI3 is multicenter, non-interventional study based on the analysis of retrospective patient data extracted from medical records and collected as part of routine clinical care following hospitalization for bronchiolitis
- Trial name
- OVNI3 (NCT07485907)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Pulmonary Arterial Hypertension of Congenital Heart Disease
Observatory of Pulmonary Arterial Hypertension of Congenital Heart Disease
The complex congenital cardiac malformations are a significant number of different diseases, each having specific natural histories.
- Trial name
- ItinerAir (NCT02260362)
- Where
- France
- Volunteers
- 349 people
- Sponsor
- French Cardiology Society
Sedentary Behavior, Exercise
Physical Activity Observatory of Castilla-La Mancha
The OBAFIT project aims to examine the patterns of physical activity, sedentary activity and health-related physical fitness of the boys and girls enrolled in schools of Primary Education and Secondary Education in Castilla-La…
- Conditions
- Sedentary Behavior, Exercise, Physical Fitness
- Trial name
- OBAFIT (NCT04994340)
- Where
- Spain
- Volunteers
- 3,280 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Nasopharyngeal Carriage, Children, Only
Nasopharyngeal Carriage of S. Pneumoniae
This nasopharyngeal (NP) carriage surveillance study was requested by the European Agency for the Evaluation of Medicinal Products as a post-licensing commitment to determine whether the use of the pneumococcal conjugate vaccines…
- Conditions
- Nasopharyngeal Carriage, Children, Only, Antibiotic Resistant Strain
- Trial name
- NCT04460313
- Testing
- nasopharyngeal sample (mandatory), Stools collection or anorectal swab samples (optional), nasopharyngeal sample (optional)
- Where
- France
- Volunteers
- 29,360 people, healthy volunteers welcome
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Polycythemia Vera, Essential Thrombocythemia
Myeloproliferative Neoplastic Diseases Observatory From Brest
All patients diagnosed or followed in Brest University Hospital for Philadelphia negative myeloproliferative neoplasms will be included in this observational study.
- Conditions
- Polycythemia Vera, Essential Thrombocythemia, Primary Myelofibrosis
- Trial name
- OBENE (NCT02897297)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Brest