Clinical trials: Observatory
Thyroid Diseases, Heart Diseases
Interest of the SPECT-CT Scan SUVspect in the New Generation of Gamma-cameras With Semiconductor
Since 2017, a revolution began in the departments of nuclear medicine, with the routine use of gamma-cameras with semiconductor.
- Conditions
- Thyroid Diseases, Heart Diseases, Bone Diseases, Brain Diseases
- Trial name
- GAMMA-CAM (NCT03414021)
- Testing
- SPECT-CT Scan
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Lille Catholic University
Myocardial Necrosis, Tako Tsubo Syndromes
French Observatory Syndromes Tako-Tsubo
Tako Tsubo syndrome (TTS) is characterized by the occurrence in the context of mental or physical stress, a clinical and ECG of acute myocardial infarction without significant coronary artery stenosis, accompanied by a disorder…
- Trial name
- OFSETT (NCT01252004)
- Where
- France
- Volunteers
- 121 people
- Sponsor
- French Cardiology Society
Puberty, Precocious
First Observatory of Precocious Puberty.
The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe.
- Trial name
- PAPPEL (NCT06263868)
- Where
- 23 sites in France
- Volunteers
- 3,360 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cardiovascular Disease
French Observatory on Hospitalizations in Cardiology of Patients of 80 Years and Over
Because of increased life expectancy and improved therapeutic methods in cardiology, the proportion of very old patients with cardiovascular disease increases.
- Trial name
- OCTOCARDIO (NCT01121679)
- Where
- France
- Volunteers
- 534 people
- Sponsor
- French Cardiology Society
Intellectual Disability
Development and Validation of the Observatory Battery of Common Eye Disorders for Adults With Intellectual Disability
Background: Around 15% of the global population has some form of disability. Rights to obtain proper health care is an emphasis in the United Nationals Convention on the Right of People with Disability.
- Trial name
- NCT06737627
- Testing
- no intervention
- Where
- 2 sites in Taiwan
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Metastatic Prostate Adenocarcinoma
Observatory of Patients With Metastatic ProstAte Adenocarcinoma That is Resistant to Castration and Multi-LinE Strategies
Evaluation the overall survival of patients with metastatic prostate adenocarcinoma resistant to castration
- Trial name
- OPALE (NCT03611686)
- Testing
- Local chemotherapy
- Where
- France
- Volunteers
- 219 people
- Sponsor
- University Hospital, Rouen
Melanoma
BRAF-/MEK-Inhibition With Dabrafenib and Trametinib in Melanoma Patients
Adjuvant therapy with dabrafenib plus trametinib in melanoma was approved in 2018 by the EMA (EUropean Medicines Agency). The purpose of this non-interventional study is to assess the usage of adjuvant dabrafenib and trametinib…
- Trial name
- Combi-EU (NCT03944356)
- Testing
- Dabrafenib and Trametinib
- Where
- 36 sites in Germany
- Volunteers
- 232 people
- Sponsor
- EuMelaReg gGmbH
Patients With Parkinson's Disease Treated With Apomorphine Pumps
Parkinsonian Patients Treated With Apomorphine Pump: Observatory of Skin Lesions
Treatment with subcutaneous apomorphine will be initiated according to the usual procedures at each centre. Once the patient is included in the study, he/she will be followed for 24 months according to a schedule of visits…
- Trial name
- POLEMIC (NCT05331573)
- Testing
- apomorphine pump
- Where
- 7 sites in France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Rouen
Cardiovascular Diseases, Digital
Cardiovascular Digital Health Data Observatory
The COVID-19 health crisis has led to a drastic decrease in the rate of myocardial infarction without the causes being completely identified.
- Conditions
- Cardiovascular Diseases, Digital, Health Data, Observatory
- Trial name
- CADHO (NCT05316025)
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Grenoble
Bilateral Upper Limb Amputation, Transverse Short Amputation of the Hand
Bilateral Upper Limb Amputation Observatory
In France, there is currently no data to directly estimate the number of bilateral upper limb amputations, their characteristics and therapeutic care.
- Conditions
- Bilateral Upper Limb Amputation, Transverse Short Amputation of the Hand, Arm Amputation
- Trial name
- ARMOBS (NCT02835378)
- Testing
- No intervention
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Patient With an Indication of Colonoscopy for Inflammatory Bowel Disease
National Multicentric Observatory of Low Bowel Preparations in Patients With IBD
National multicentric observatory of low bowel preparations in patients with IBD
- Trial name
- CLEAN (NCT03753425)
- Testing
- Low volume bowel preparation in inflammatory bowel diseases
- Where
- France
- Volunteers
- 278 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Hematopoietic Stem Cell Transplantation, Cytomegalovirus Infections
AntiCMV molécules Monitoring in Real-life in Stem Cell Recipients
Cytomegalovirus (CMV) is a ubiquitous herpesvirus that represent a major cause of morbidity in haematopoietic stem cell transplants (HSCT) recipients, mostly through reactivation of the recipient's virus.
- Conditions
- Hematopoietic Stem Cell Transplantation, Cytomegalovirus Infections, Antivirals, Antiviral Drug Resistance
- Trial name
- NAViRe (NCT04690933)
- Testing
- Real-life observatory of efficacy and resistance to anti CMV molecules in stem cell recipients
- Where
- 16 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Limoges
Helicobacter Pylori Infection
French Pediatric Helicobacter Pylori Observatory
Helicobacter pylori is a major human pathogen associated with significant morbidity. The treatment oriented by the antibiogram or PCR (Polymerase Chain Reaction) should be privileged in children.
- Trial name
- GFHPP (NCT03541876)
- Testing
- Collection of data
- Where
- France
- Volunteers
- 1,201 people
- Sponsor
- Lille Catholic University
Multiple Myeloma
Finistere Myeloma Observatory (OMYFIN)
Current molecular risk stratification of multiple myeloma (MM), based on the presence of t(4 ;14) and 17p deletion, cannot fully explain treatment outcome heterogeneity, as other features also predict prognosis.
- Trial name
- OMYFIN (NCT06552221)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Covid-19
Use of PCR-Sars-CoV-2 in Children
The VIGIL study was set up at the beginning of the pandemic, in the spring of 2020, at a time when diagnostic testing for SARS-CoV-2 had to be performed according to specific clinical criteria (even if no clinical picture…
- Trial name
- VIGIL (NCT04412317)
- Where
- 2 sites in France
- Volunteers
- 12,000 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Lung Cancer
French Biological Observatory on Lung Cancer in Never Smokers
Lung cancer in non-smokers (LCINS) is an increasing public health problem. The BioCAST (IFCT-1002) study, promoted by Intergroupe Francophone de Cancérologie Thoracique (IFCT), focuses on this entity.
- Trial name
- BioCAST (NCT01465854)
- Where
- 82 sites in France
- Volunteers
- 422 people
- Sponsor
- Intergroupe Francophone de Cancerologie Thoracique
Carcinoma, Non-Small-Cell Lung, ALK Gene Mutation
French National Observatory of the Patients With Non-small Cell Lung (NSCLC) and Molecular Testings
The French National Cancer Institute (INCa) support a 28 hospital platforms network for molecular testing of cancer patients. These platforms routinely assess a panel of biomarkers in order to speed up access of French cancer…
- Conditions
- Carcinoma, Non-Small-Cell Lung, ALK Gene Mutation, KRAS Gene Mutation, BRAF Gene Mutation
- Trial name
- NCT01700582
- Where
- 133 sites in France
- Volunteers
- 17,664 people
- Sponsor
- Intergroupe Francophone de Cancerologie Thoracique
Antibiotic Sore Tongue
Antibiotic Observatory for Respiratory Diseases, Apart From Tuberculosis and Reportable Diseases
the study aimed to determine the distribution of respiratory infections in Tunisian population and evaluate the frequency of antibiotics prescribed according to current international recommendations.
- Trial name
- AORD (NCT04482231)
- Where
- Tunisia
- Volunteers
- 9,944 people
- Sponsor
- University of Monastir
Acute Heart Failure
French Observatory of Acute Heart Failure
During the last decade, progress has been made in the management of heart failure. However, the changing characteristics of patients and practices in the "real world" and their impact on the prognosis of patients admitted for…
- Trial name
- OFICA (NCT01080937)
- Where
- France
- Volunteers
- 1,818 people
- Sponsor
- French Cardiology Society
Cardiogenic Shock
French Observatory on the Management of Cardiogenic Shock 2
The aim of this observational study is to describe the baseline characteristics, management strategies, and early outcomes (during hospitalisation and at 30 days) of patients admitted to intensive care with cardiogenic shock…
- Trial name
- FRENSHOCK 2 (NCT07868757)
- Where
- 2 sites in France
- Volunteers
- 1,000 people
- Sponsor
- French Cardiology Society