Clinical trials: Obstructive Sleep Apnea
Obstructive Sleep Apnea
Tonsillectomy in Adults With Tonsillar Hypertrophy and Obstructive Sleep Apnea
The purpose of the study is to determine if tonsillectomy eliminates symptoms of obstructive sleep apnea in patients with obstructive sleep apnea and marked tonsillar hypertrophy with normal soft palate and uvula length.
- Trial name
- NCT02204696
- Testing
- Tonsillectomy
- Where
- United States
- Sponsor
- University of Southern California
Sleep Apnea, Obstructive
Safety Study of Quickclot for Bleeding Control After Adenotonsillectomy
Hemostasis will be achieved during Pediatric Tonsillectomy/Adenoidectomy with the use of QuickClot.
- Trial name
- NCT01863563
- Testing
- QuickClot
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Eastern Virginia Medical School
Adenotonsillectomy, Obstructive Sleep Apnea (OSA)
Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstructive Sleep Apnea
Emphasize that the usage of multimodal analgesia in managing perioperative pain in children with mild to moderate Obstructive Sleep Apnea undergoing adenotonsillectomy may achieve the same efficacy of fentanyl with less…
- Conditions
- Adenotonsillectomy, Obstructive Sleep Apnea (OSA), Fentanyl, Opioid
- Trial name
- NCT07435493
- Testing
- Group A: Fentanyl-Based Analgesia, Group B: Opioid-Free Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea
Adaptation and Validation of Pediatric Sleep Questionnaire (PSQ) in Arabic
The gold-standard in the diagnosis of Sleep-Related Breathing Disorders (SRBDs) is polysomnography, but the time, effort, and expense of laboratory studies has limited relevant research and particularly epidemiological research…
- Trial name
- NCT06141707
- Testing
- Arabic pediatric sleep questionnaire
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Minia University
Down Syndrome, Obstructive Sleep Apnea
Investigating the Experience of Living With Down Syndrome and Obstructive Sleep Apnea Syndrome (Stage 1)
To identify the perceptions, beliefs, and family-relevant outcomes regarding the treatment of obstructive sleep apnea syndrome (OSAS) with positive airway pressure (PAP) in children with Down's Syndrome (DS).
- Trial name
- NCT04124471
- Testing
- Open-ended semi-structured interviews
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital of Philadelphia
Obstructive Sleep Apnea of Child
SleepPOSAtive Trial
This is a randomized crossover trial of children diagnosed with positional obstructive sleep apnea (POSA) on a baseline polysomnogram (PSG).
- Trial name
- NCT05499455
- Testing
- Positional Sleep Belt, Control
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- The Hospital for Sick Children
Obstructive Sleep Apnea, Tonsillitis
Pediatric Pain Optimization After Tonsillectomy
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery.
- Conditions
- Obstructive Sleep Apnea, Tonsillitis, Pain, Procedural
- Trial name
- NCT05244226
- Testing
- Fentanyl/Hydromorphone, Methadone
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Duke University
Obstructive Sleep Apnea of Child
Surgical Versus Nonsurgical Treatment on Quality of Life for Children With Controversial OSA Diagnoses
Obstructive sleep apnea (OSA) is a disease characterized by repeated partial or complete upper airway collapse during sleep, accompanied by arousals or oxygen desaturation.
- Trial name
- NCT03370731
- Testing
- adenotonsillectomy, Nonsurgical management
- Where
- 4 sites in China
- Volunteers
- 60 people
- Sponsor
- Beijing Tongren Hospital
Obstructive Sleep Apnea
Long-term Impact of Maxillomandibular Advancement Osteotomy on Sleep Apnea Patients
Background Maxillomandibular advancement surgery (MMA) has demonstrated high success rates, improving both the apnea-hypopnea index and associated patient' quality of life (QOL), in patients diagnosed with obstructive sleep apnea…
- Trial name
- MIMOSA (NCT03246477)
- Volunteers
- 12 people
- Sponsor
- AZ Sint-Jan AV
Obstructive Sleep Apnea
Microbiome and Metabolomics Profiling in Children With OSA
Objectives: Obstructive sleep apnoea (OSA) exhibits variable susceptibility to end-organ morbidities. Previous studies suggest that physiological sequelae in individuals with OSA promote changes in microbiome, which also interact…
- Trial name
- NCT06452992
- Where
- Hong Kong
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea
Outcome of Laser or Debrider Tonsillotomy Versus Tonsillectomy in Obstructive Sleep Apnea
Tonsil surgery for children suffering from obstructive sleep apnea have significant post operative morbidity including pain and occasionally bleeding. This morbidity is partly caused by post surgical inflammation.
- Trial name
- TVLOD (NCT01319058)
- Testing
- Tonsillectomy, laser tonsillotomy, debrider tonsillotomy
- Where
- Israel
- Volunteers
- 88 people
- Sponsor
- Soroka University Medical Center
Obstructive Sleep Apnea Syndrome
Inflammatory Markers in Infants With Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) is a common disorder in children (2-3%). OSAS in turn, is associated with significant behavioral, learning, and heart problems.
- Trial name
- NCT01058590
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Apnoea, Prematurity
Automated Apnoea Detection in Preterms on Non-invasive Ventilation
The aim of this study is to monitor the frequency of apnoeas (pauses in breathing) on various methods of non-invasive respiratory support that are detected by an automated machine-learning (ML) model based on diaphragmatic…
- Trial name
- NCT07794007
- Testing
- Diaphragmatic electromyography
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Sleep Apnea, Obstructive
Obstructive Sleep Apnea Syndrome (OSA) and Getemed
It is often clinically impossible to differentiate children with an isolated snoring from those with OSA. The diagnosis of OSA is currently based on nocturnal, laboratory-based polysomnography.
- Trial name
- GETEMED (NCT01720823)
- Testing
- home polysomnography (GETEMED), standard polysomnography (BRAINNET II)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Hospices Civils de Lyon
Pain, Postoperative, Obstructive Sleep Apnea of Child
Use of Analgesics and Pain Scores After Pediatric Adenotonsillectomy
The purpose of the study is to quantify the use of pain medications given to children aged 3 - 12 years as well as their pain level through pain scores after they have undergone a tonsillectomy or adenotonsillectomy surgery at…
- Trial name
- NCT04349397
- Testing
- Medication Tracking Form
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Obstructive Sleep Apnea of Child
Single Cell Sequencing of Tonsillar Tissue in Children With OSA
Obstructive sleep apnoea (OSA) in children is a prevalent sleep disorder, and is characterised by repetitive complete or partial upper airway obstruction during sleep.
- Trial name
- NCT05115968
- Testing
- Tonsillectomy
- Where
- Hong Kong
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Asthma, Sleep Disordered Breathing
Personalized Asthma Care Team
"Individualized health care" refers to the development of strategies for disease management and health promotion that are informed by specific data on genetics and physiological processes that uniquely determine each person's…
- Conditions
- Asthma, Sleep Disordered Breathing, Obesity
- Trial name
- PACT (NCT01423461)
- Volunteers
- 201 people
- Sponsor
- Brigham and Women's Hospital
Chronic Obstructive Pulmonary Disease, Neuromuscular Disease
Telemedicine and Ventilator Titration in Chronic Respiratory Patients Initiating Non-invasive Ventilation
The critical nature of respiratory diseases, the continuously increasing prevalence of these conditions, and the subjective perception of patients vis-à-vis their pulmonary function and health status underscore the importance of…
- Conditions
- Chronic Obstructive Pulmonary Disease, Neuromuscular Disease, Chest Wall Disorders, Obesity Hypoventilation Syndrome
- Trial name
- TeleMotiNIV (NCT01560741)
- Testing
- Telemonitoring tools, Usual Care
- Where
- Portugal
- Volunteers
- 128 people
- Sponsor
- Hospital Sao Joao
Obstructive Sleep Apnea, Pediatric Sleep Apnea
Measurement of Cerebral rSO2 Levels During Sleep in Children With Suspected Obstructive Sleep Apnea
The gold standard of obstructive sleep apnea (OSA) is (PSG)POLYSOMNOGRAPHY. During the examination, the patient is monitored by saturation, EEG and other measurements.
- Trial name
- O2SLEEP (NCT04321083)
- Testing
- INVOS
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Sleep Apnea, Obstructive
Pediatric Obstructive Sleep Apnea Diagnosis by Respiratory Polygraphy
Respiratory polygraphy (RP) can be used to detect obstructive sleep apnea syndrome in children (OSA) , but it underestimates the obstructive apnea-hypopnea index (OAHI) because hypopneas associated with cortical arousals are not…
- Trial name
- NCT06754800
- Testing
- Polysomnography in routine care
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Central Hospital, Nancy, France