Clinical trials: Ocular Motility Disorders
Blepharospasm, Torticollis
MDs on Botox Utility (MOBILITY)
The MOBILITY Project is a prospective, non-randomized, observational, multi-centre evaluation of Health Utility via the SF-12® Health Survey Scores and the SF-6D in patients receiving BOTOX® for therapeutic use.
- Conditions
- Blepharospasm, Torticollis, Strabismus, Muscle Spasticity
- Trial name
- NCT00535938
- Testing
- botulinum toxin type A
- Where
- Canada
- Volunteers
- 1,372 people
- Sponsor
- Allergan
ADHD - Attention Deficit Disorder With Hyperactivity
Evaluation of the Relationship Between Medication, Eye Movements, and Autonomic Nervous System (ANS) Functions in Children and Adolescents With ADHD
An increasing number of children are being diagnosed with ADHD, and the demand for ADHD medication has been rising. Although ADHD medication is often effective, this is unfortunately not the case for all children and adolescents…
- Trial name
- POP-Eye/ANSA (NCT07634809)
- Testing
- metylphenidate
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Umeå University
Amblyopia, Strabismus
Screening for 3-D Visual Disorders in Preschool Children
Visual screening is necessary among pre-school children as they found themselves in a critical period of visual developement. To date, there are no national vision screening program that has been implemented nationwide.
- Conditions
- Amblyopia, Strabismus, Anisometropia
- Trial name
- VISION (NCT05204069)
- Testing
- Instillation of cyclopentolate
- Where
- France
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Exotropia
Comparison of Medial Rectus Resection and Plication in Exotropic Patients
Purpose: To determine the surgical outcomes of the plication technique in comparison with the resection method on exotropic patients.
- Trial name
- NCT03768362
- Testing
- Plication strabismus surgery, Resection strabismus surgery
- Volunteers
- 52 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Strabismus, Esotropia
Risk Factors And Surgical Outcomes Of Strabismus Reoperation
Horizontal strabismus, commonly known as inward or outward deviation of the eyes, is a frequent eye condition that may require surgical correction.
- Conditions
- Strabismus, Esotropia, Exotropia
- Trial name
- RSOR (NCT07446621)
- Testing
- Horizontal Strabismus Reoperation
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Ocular Motility Disorders
Oculomotor Training Improves Reading Eye Movement
Children with reading eye movement problems were recruited for this study. The treatment group was provided with oculomotor training for 8 weeks, the control group was given placebo exercises.
- Trial name
- NCT02981875
- Testing
- oculomotor training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Niemann Pick Diseases
Saccadic Eye Movements in Patients With Niemann-Pick Type C Disease
This study is done in conjunction with a trial, conducted at Columbia University College of Physicians and Surgeons in New York and the Royal Manchester Children's Hospital in England, to examine the effectiveness of a new drug…
- Trial name
- NCT00316498
- Testing
- OGT918
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 30 people
- Sponsor
- National Eye Institute (NEI)
Surgical Procedure, Unspecified, Ocular Discomfort
Lateral Rectus Muscle Tendon Elongation
To evaluate a technique using resected medial rectus muscle transplantation for elongation of Lateral rectus tendon as a monocular surgery for large angle sensory exotropia.
- Conditions
- Surgical Procedure, Unspecified, Ocular Discomfort, Strabismus, Divergent
- Trial name
- NCT04286945
- Testing
- LATERAL RECTUS MUSCLE AUGMENTED RECESSION BY ELONGATION OF THE TENDON WITH AUTOGRAFT FROM RESECTED MEDIAL RECTUS MUSCLE
- Volunteers
- 16 people
- Sponsor
- Tanta University
REM Behavior Disorder, Parkinsonism
Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism
Parkinson's disease (PD) is the second most common neurodegenerative disorder of the elderly that affects a million patients in US. Sleep dysfunction impacts up to 90% of PD patients.
- Trial name
- NCT00745030
- Testing
- Rozerem
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Northwestern University
Convergence Insufficiency
Efficacy Of Pencil Pushup Exercise Vs Base Out Exercising Prism's In Patient With Convergence Insufficiency
Convergence insufficiency (CI) is a prevalent binocular vision disorder that leads to symptoms such as eye strain, headaches, and blurred vision during near work.
- Trial name
- NCT06913829
- Testing
- base-out exercising prisms, pencil pushup exercises
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Superior University
Strabismus
Symmetrical Versus Asymmetrical Surgery for Asymmetrical Inferior Oblique Overaction
Overaction of the inferior oblique (IO) muscle is a commonly observed component of childhood strabismus, and is often seen combined with other ocular deviations.
- Trial name
- NCT03507712
- Testing
- Symmetrical IO weakening, Asymmetrical IO weakening
- Where
- Oman
- Volunteers
- 28 people
- Sponsor
- Sultan Qaboos University
Anesthesia, Strabismus
Post-Operative Nausea and Vomiting in Children Submitted to Strabismus Surgery
Background: Postoperative nausea and vomiting (PONV) is one of the main causes of patient and family dissatisfaction, which may delay the onset of oral intake and postpone discharge.
- Conditions
- Anesthesia, Strabismus, PONV
- Trial name
- NCT04060771
- Testing
- Palonosetron, Dexamethasone
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade Federal Fluminense
Strabismus
Balance in the Strabismic Patient Undergoing Strabismus Surgery
Strabismus is a clinical condition characterized by the failure of the visual axes of the two eyes to align on the stared object.
- Trial name
- BASS (NCT06733220)
- Testing
- Surgery for strabismus
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Esotropia
Early Versus Delayed Surgery for Infantile Esotropia
The goal of this study is to determine whether corrective surgery done earlier than the current standard can better improve the visual and eye movement deficits in children with infantile esotropia (crossed eyes in infancy).
- Trial name
- NCT01166503
- Testing
- mVEP Testing, Stereoacuity Testing, Optokinetic nystagmus testing
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- The Hospital for Sick Children
Anxiety, Strabismus
Does Anxiety in Children on the Day of Surgery Impact Compliance in the Ophthalmology Clinic?
The hypothesis is that pediatric patients with increased levels of anxiety on the day of surgery, in particular at point of anesthetic induction, will demonstrate decreased compliance with assessment in ophthalmology clinic…
- Conditions
- Anxiety, Strabismus, Compliance
- Trial name
- NCT02704442
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Queen's University
Amblyopia, Strabismus
Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner
The purpose of this project is to compare the performance of the Pediatric Vision Scanner (PVS) with the Gold Standard Examination to determine the effectiveness of the PVS at detecting amblyopia and strabismus.
- Trial name
- NCT01832883
- Testing
- Pediatric Vision Scanner
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Opsoclonus-myoclonus Syndrome
Study of Cytokines in Children With Opsoclonus-Myoclonus Syndrome
The purpose of this study is to determine if cytokines, inflammatory mediators, are increased in spinal fluid and blood, correlate with disease activity, and could serve as biomarkers or therapeutic targets in children with…
- Trial name
- OMS (NCT00806182)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Pediatric Neuroinflammation Organization, Inc.
Low Vision, Age Related Macular Degeneration
Eye Movement Rehabilitation in Low Vision Patients
Approximately 217 million people worldwide currently suffer from low vision, which impacts a broad range of activities of daily living and is associated with depression and increased mortality.
- Trial name
- NCT04929756
- Testing
- Visual Feedback
- Where
- 2 sites in United States
- Volunteers
- 106 people
- Sponsor
- Northeastern University
Amblyopia, Strabismus
New Pediatric Patching Method to Improve Compliance
This project will assess whether there is a significant difference in compliance with patching in amblyopic patients whose parents are instructed to pinch the superior and inferior edges of the patch before applying (in order to…
- Trial name
- NCT02236351
- Testing
- Pinch Patch/ flat Patch
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Baylor College of Medicine
Postoperative Nausea and Vomiting
Late Onset Postoperative Nausea and Vomiting
The purpose of this trial is to study the effects of different combinations of antiemetics on the incidence of late onset postoperative nausea and vomiting.
- Trial name
- NCT00918190
- Testing
- Ondansetron, Dexamethasone, Midazolam, dexamethasone
- Where
- Saudi Arabia
- Volunteers
- 75 people
- Sponsor
- King Khaled Eye Specialist Hospital