Clinical trials: Oncologic
Physician Satisfaction With the Outcomes of Cytotoxic Drugs
Oncologists Satisfaction With Outcomes of Some Cytotoxic Agents
The study measures the degree of oncology physician satisfaction with the outcomes of some cytotoxic agents.
- Trial name
- NCT02630979
- Testing
- Measuring satisfaction, knowledge and bias
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Cardiotoxicity
Remote Ischaemic Preconditioning in Childhood Cancer
Survival rates of children with cancers have improved significantly in the recent few decades. Nonetheless, the side effect of this class of drugs on heart function remains to be an issue of concern.
- Trial name
- NCT03166813
- Testing
- Remote Ischaemic Preconditioning, Control
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- The University of Hong Kong
Hemiplegia, Brain Tumor
Constraint-Induced Movement Therapy in a Pediatric Oncology Population
Hemiplegia (weakness or poor muscle function on one side of the body) is a neurological impairment which can occur in children as a result of a brain tumor or related treatment.
- Trial name
- SJCIT (NCT01447810)
- Testing
- Focused rigidity bi-valve long arm cast
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St. Jude Children's Research Hospital
Acute Respiratory Distress Syndrome, Sepsis
Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis
The overall purpose of this protocol is to identify subacute sepsis-associated cardiac disease in pediatric patients with cancer by CMR and evaluate the CMR findings during their follow-up.
- Conditions
- Acute Respiratory Distress Syndrome, Sepsis, Cardiovascular Shock
- Trial name
- NCT05930418
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia
ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia (ALL) - 6MP Consolidation Therapy
The purpose of this study is to increase the fraction of patients, who become MRD-negative during consolidation for the non-HR ALL group through individualized intensification of the 6MP-dosage days 30-85.
- Trial name
- ALL2008con (NCT00816049)
- Testing
- 6MPindividualized, 6MPfixed
- Where
- 6 sites in Denmark, Finland and 3 more
- Volunteers
- 775 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Oncology, Haematological Malignancy
Central Venous Access Device Removal in Cancer Patients
Background: Central venous catheters are frequently used during cancer treatment with the aim of venepreservation. It can facilitate venous access for the safe administration of irritating or vesicant intravenous cancer…
- Trial name
- NCT03855969
- Testing
- Removal of a central venous access device
- Where
- Belgium
- Volunteers
- 1,402 people
- Sponsor
- General Hospital Groeninge
Colon Cancer, Laparoscopic Colon Surgery
Analysis of Surgical and Oncologic Outcomes After Complete Mesocolic Excision or Non-complete Mesocolic Excision for Right-Sided Colon Cancer
The goal of this observational study is to investigate the efficacy and safety of a modified D3 lymphadenectomy approach compared to Complete Mesocolic Excision (CME) in patients with right-sided colon cancer.
- Conditions
- Colon Cancer, Laparoscopic Colon Surgery, Lymph Node Dissection, Robotic Surgical Procedures
- Trial name
- NCT06684223
- Where
- South Korea
- Volunteers
- 3,787 people
- Sponsor
- Asan Medical Center
Cancer, Oncology
The ROAD 2.0 to Sustainable Medication Use: Redispensing Unused Oral Anticancer Drugs
The goal of this prospective intervention study is to investigate the effectiveness of redispensing unused oral anticancer drugs.
- Conditions
- Cancer, Oncology, Pharmacy, Drug Prescriptions
- Trial name
- NCT06566560
- Testing
- redispensing oral anticancer drugs
- Where
- Netherlands
- Volunteers
- 2,500 people
- Sponsor
- Radboud University Medical Center
Diarrhea
Epidemiology of Diarrheal Diseases in Pediatric Oncology Patients
Diarrhea is a common problem in the pediatric population. Children with cancer are especially at increased risk for gastrointestinal infection-related morbidity and mortality due to their ongoing immunosuppression.
- Trial name
- NCT02464098
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- St. Jude Children's Research Hospital
Breast Cancer Females, Oncology
Effects of a Group Versus Individual Cognitive Training Program on Chemotherapy-induced Cognitive Impairment (Chemobrain) in Breast Cancer Patients Undergoing Active Treatment
Introduction: The significant improvement in breast cancer survival, largely attributable to biomedical and technological progress, makes it increasingly necessary to investigate the secondary effects linked to this pathology.
- Trial name
- NCT07165912
- Testing
- Health Education Program, Individual Cognitive Training Program, Group training program
- Where
- 2 sites in Spain
- Volunteers
- 75 people
- Sponsor
- University of Salamanca
Quality of Life Outcomes
Palliative Care Integration in Pediatric Oncology Phase 1 Clinical Trials
Although cure rates continue to rise, one in five children with cancer still die from their disease, so new therapies are urgently needed.
- Trial name
- NCT07696065
- Testing
- Pediatric Palliative Care Consultation
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Phoenix Children's Hospital
Radiation Oncology
Radiation Treatment Plan Evaluation Learning Tool Pilot Project
This study involves both the development of a novel learning tool, the Radiation Treatment Plan Evaluation Learning Module, as well as a pilot program to validate this tool as an effective resource to teach treatment plan review…
- Trial name
- NCT06115811
- Testing
- Radiation Treatment Plan Evaluation Learning Tool
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Childhood Cancer
PET/MRI and PET/CT in Diagnosing Younger Patients With Cancer
This pilot clinical trial studies how well positron emission tomography (PET)/magnetic resonance imaging (MRI) works compared to PET/computed tomography (CT) in diagnosing younger patients with cancer.
- Trial name
- NCT02287636
- Testing
- fludeoxyglucose F 18, positron emission tomography, computed tomography
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Case Comprehensive Cancer Center
H1N1 Influenza Virus, Invasive Solid Tumors
Clinical Trial to Compare the Immunogenicity, Safety, and Tolerability of an Adjuvanted A(H1N1) Influenza Vaccine Versus Non-Adjuvanted A(H1N1) Influenza Vaccines in Patients With Invasive Solid Tumors
This is a phase III, randomized, controlled, open label study with two vaccine regimens. The study will assess the relative safety and immunogenicity of vaccine regimens comparing adjuvanted versus non-adjuvanted formulations of…
- Trial name
- NCT01031719
- Testing
- adjuvanted A(H1N1) influenza vaccine, non-adjuvanted A(H1N1) influenza vaccine
- Where
- 3 sites in Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Chiltern Pesquisa Clinica Ltda
Pediatric Cancers
Palliative Care and Symptom Management for the Pediatric Oncology Patient
The goal of this study is to learn about the communication, decision-making, symptom management, emotional adjustment, and spiritual needs of parents and pediatric patients treated at the Children's Cancer Hospital at M. D.
- Trial name
- NCT00675467
- Testing
- Focus Group - Parent/Caregiver, Focus Group - Pediatric Patient
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- M.D. Anderson Cancer Center
Neoplasm
Development of a Platform for the Clinical Implementation of Precision Oncology in the Central-Southern Regions of Italy (COESIT)
COESIT aims to establish a network of reference laboratories in the central-southern regions of Italy for the genetic and molecular characterization of tumors, with the goal of implementing precision and personalized oncology in…
- Trial name
- NCT06894823
- Testing
- Creation of a laboratory network, Mapping of genomic alterations, Creation of a bioinformatics network among the participating institutions.
- Where
- Italy
- Volunteers
- 16,000 people
- Sponsor
- National Cancer Institute, Naples
Emotional Well-being, Quality of Life
Robotic Dog Intervention on Emotional Well-Being and Quality of Life
The hematopoietic stem cell transplantation (HSCT) process imposes a substantial psychological burden, leading to impaired emotional well-being due to intensive treatment, isolation, and immunosuppression.
- Conditions
- Emotional Well-being, Quality of Life, Pediatric Oncology
- Trial name
- ROBDOG (NCT07607379)
- Testing
- AIBO
- Volunteers
- 28 people
- Sponsor
- Koç University
Acute Kidney Injury, Renal Tubulopathy
Prevention of Cisplatin-induced Nephrotoxicity
The research design is a prospective, randomized, controlled clinical trial in children to study effect of aminophylline in preserving renal function in oncologic patient received cisplatin either combined with other CMT or used…
- Trial name
- NCT06196853
- Testing
- Aminophylline
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Oncology
Irreversible Electroporation for Treatment of Solid Abdominal Tumors
Irreversible electroporation (IRE) is a novel non-thermal ablation modality with promise for revolutionizing the treatment for local solid tumors.
- Trial name
- NCT03169439
- Testing
- Irreversible electroporation
- Volunteers
- 25 people
- Sponsor
- Assiut University
Desmoid Tumor
Vinblastine and Methotrexate in Treating Children With Desmoid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003019
- Testing
- methotrexate, vinblastine sulfate
- Where
- 39 sites in United States, Australia and 1 more
- Volunteers
- 28 people
- Sponsor
- Children's Oncology Group